Distinguish Coding And Noncoding Sequences In A Complete Genome Using Fourier Transform

A Fourier transform method is proposed to distinguish coding and non-coding sequences in a complete genome based on a number sequence representation of the DNA sequence proposed in our previous paper (Zhou et al., J. Theor. Biol. 2005) and the imperfect periodicity of 3 in protein coding sequences. The three parameters P_x(S) (1), P_x(S) (1/3) and P_x(S) (1/36) in the Fourier transform of the number sequence representation of DNA sequences are selected to form a three-dimensional parameter space. Each DNA sequence is then represented by a point in this space. The points corresponding to coding and non-coding sequences in the complete genome of prokaryotes are seen to be divided into different regions. If the point (P_x(�ar S) (1), Px(�ar S) (1/3), P_x(�ar S) (1/36)) for a DNA sequence is situated in the region corresponding to coding sequences, the sequence is distinguished as a coding sequence; otherwise, the sequence is classified as a noncoding one. Fisher's discriminant algorithm is used to study the discriminant accuracy. The average discriminant accuracies pc, pnc, qc and qnc of all 51 prokaryotes obtained by the present method reach 81.02%, 92.27%, 80.77% and 92.24% respectively

Determining weak phase gamma and probing new physics in b->s transitions from B->eta(eta')K

We present a method of determining weak phase \gamma in the Cabibbo-Kobayashi-Maskawa matrix from decays B->\eta K, \eta' K$alone. Given a large ratio between color-suppressed and color-allowed tree diagrams extracted from global \pi\pi(K) fits, \gamma is determined from the current data of \eta' K and the result is in agreement with the global Standard Model(SM) fits. However, a smaller ratio from factorization based calculations gives$\gamma\sim 90^\circ$. New physics beyond the SM can be singled out if\gamma obtained in \eta^{(')} K modes is significantly different than the ones from other modes or other approaches. The effective value of \gamma from \eta' K is very sensitive to new physics contributions and can be used to extract new physics parameters for a class of models which do not give contributions to strong phases significantly.Comment: 18 pages, 2 figures, version to appear in Eur.Phys.J.