17 research outputs found

    Assessing slope forest effect on flood process caused by a short-duration storm in a small catchment

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    Land use has significant impact on the hydrologic and hydraulic processes in a catchment. This work applies a hydrodynamic based numerical model to quantitatively investigate the land use effect on the flood patterns under various rainfall and terrain conditions in an ideal V-shaped catchment and a realistic catchment, indicating the land use could considerably affect the rainfall-flood process and such effect varies with the catchment terrain, land use scenario and the rainfall events. The rainfall-flood process is less sensitive for the side slope than the channel slope. For a channel slope lower than the critical value in this work, the forest located in the middle of the catchment slope could most effectively attenuate the flood peak. When the channel slope is higher than the critical one, forest located in the downstream of the catchment could most significantly mitigate the peak discharge. Moreover, the attenuation effect becomes more obvious as the rainfall becomes heavier. The fragmentation of vegetation does not reduce the flood peak in a more obvious way, compared with the integral vegetation patterns with the same area proportion. The research can help more reasonably guide the land use plan related to flood risk

    MicroRNA-126 inhibits cell invasion and tumor growth.

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    <p>(A) Overe-xpression of microRNA-126 inhibits the cell invasion in A549 and SK-MES-1 cells. Compared with the control group, over-expression of microRNA-126 impaires cell invasion. (B) MicroRNA-126 impairs the cell proliferation in A549 and SK-MES-1 cells. The cell proliferation was dramatically decreased after cells were treated with microRNA-126 over-expression for 72 hours. (C) The tumor growth curve <i>in vivo</i> by intratumoral injection with microRNA-126. The growth of tumors was observed from 1 to 25 days after the last injection. (D) MicroRNA-126 inhibits growth of A549 cell and SK-MES-1 cells in vivo. The average tumor only about an half of the tumors weight in the mice treated with PBS or pE-CMV vector alone.</p

    The expression levels of microRNA-126 in Non-small cell lung cancers.

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    <p>The expression levels of microRNA-126 in Non-small cell lung cancers.</p

    Low expression levels of microRNA-126 correlate with poor survival of NSCLC patients.

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    <p>(A) The expression levels of microRNA-126 are decreased in NSCLC cell lines. Expression of microRNA-126 was examined by quantitative real-time PCR in NL20 cell lines and NSCLC cell lines. (B) The expression levels of microRNA-126 are decreased in Human NSCLC specimens. Expression of microRNA-126 was determined by quantitative real-time PCR in tumor tissues and patient-matched adjacent lung tissues. Compared with the corresponding adjacent lung tissues, microRNA-126 expression was markedly down-regulated in tumor tissues (<i>P</i><0.0001). (C) Low microRNA-126 expression correlates with poor survival of NSCLC patients. Patients were divided into two groups based on their microRNA-126 expression levels: those with less than median of microRNA-126 expression levels and those with more than or equal to median of microRNA-126 expression levels (median: 0.654). The patients with low microRNA-126 expression had significantly poor survival time compared with those with high microRNA-126 expression (means for survival time (month):24.392±1.055 vs. 29.282±1.140, <i>P</i> = 0.005).</p

    Genetic variant within microRNA-126 is not associated with the survival times and microRNA-126 expression levels in NSCLC patients.

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    <p>(A) Genetic variant within microRNA-126 is not associated with survival times. Kaplan-Meier survival estimates show that there is no association between SNP rs4636297 and survival time in NSCLC patients (<i>P</i> = 0.992). (B). Expression levels of microRNA-126 in NSCLC tissues of three genotypes are similar. MicroRNA-126 expression was determined by quantitative real-time PCR. There was no significant difference among the three genotype groups (<i>P</i> = 0.972).</p

    The expression levels of PIK3R2 and the phosphorylation levels of Akt in NSCLC tissues.

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    a<p>Patients were divided into two groups with low and high microRNA-126 expression levels, based on their microRNA-126 expression levels: those with less than median of microRNA-126 expression levels and those with more than or equal to median of microRNA-126 expression levels (median: 0.654).</p

    Genotype of microRNA-126 polymorphisms and their associations with NSCLC risk.

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    <p>Genotype of microRNA-126 polymorphisms and their associations with NSCLC risk.</p

    Clinical factors of patients correlate with overall survival by multivariate Cox proportional hazard regression analysis.

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    <p>Clinical factors of patients correlate with overall survival by multivariate Cox proportional hazard regression analysis.</p

    Low-Frequency Noise in Layered ReS<sub>2</sub> Field Effect Transistors on HfO<sub>2</sub> and Its Application for pH Sensing

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    Layered rhenium disulfide (ReS<sub>2</sub>) field effect transistors (FETs), with thickness ranging from few to dozens of layers, are demonstrated on 20 nm thick HfO<sub>2</sub>/Si substrates. A small threshold voltage of −0.25 V, high on/off current ratio of up to ∼10<sup>7</sup>, small subthreshold swing of 116 mV/dec, and electron carrier mobility of 6.02 cm<sup>2</sup>/V·s are obtained for the two-layer ReS<sub>2</sub> FETs. Low-frequency noise characteristics in ReS<sub>2</sub> FETs are analyzed for the first time, and it is found that the carrier number fluctuation mechanism well describes the flicker (1/<i>f</i>) noise of ReS<sub>2</sub> FETs with different thicknesses. pH sensing using a two-layer ReS<sub>2</sub> FET with HfO<sub>2</sub> as a sensing oxide is then demonstrated with a voltage sensitivity of 54.8 mV/pH and a current sensitivity of 126. The noise characteristics of the ReS<sub>2</sub> FET-based pH sensors are also examined, and a corresponding detection limit of 0.0132 pH is obtained. Our studies suggest the high potential of ReS<sub>2</sub> for future low-power nanoelectronics and biosensor applications

    Mitigating <i>V</i><sub>oc</sub> Loss in Tin Perovskite Solar Cells via Simultaneous Suppression of Bulk and Interface Nonradiative Recombination

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    Tin-based perovskite solar cells (PSCs) have recently attracted extensive attention as a promising alternative to lead-based counterparts due to their low toxicity and narrow band gap. However, the severe open-circuit voltage (Voc) loss remains one of the most significant obstacles to further improving photovoltaic performance. Herein, we report an effective approach to reducing the Voc loss of tin-based PSCs. We find that introducing ethylammonium bromide (EABr) as an additive into the tin perovskite film can effectively reduce defect density both in the tin perovskite film and at the surface as well as optimize the energy level alignment between the perovskite layer and [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) transport material, thereby suppressing nonradiative recombination both in the bulk film and at the interface. Furthermore, it is demonstrated that the Voc loss is gradually mitigated along with increasing storage duration due to the slow passivation effect. As a result, a remarkable Voc of 0.83 V is achieved in the devices optimized with the EABr additive, which shows a significantly improved power conversion efficiency (PCE) of 10.80% and good stability
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