State funded places in independent day schools before 1976

Transfection efficiency of Ad-A20 and Ad-ABIN1. Transfection efficiencies were determined using signals of GFP co-expression from Ad-A20 and Ad-ABIN1 vectors. The efficiencies were approximately > 90 %. (TIFF 2031 kb

A Sequential Strand-Displacement Strategy Enables Efficient Six-Step DNA-Templated Synthesis

We developed a sequential strand-displacement strategy for multistep DNA-templated synthesis (DTS) and used it to mediate an efficient six-step DTS that proceeded in 35% overall yield (83% average yield per step). The efficiency of this approach and the fact that the final product remains linked to a DNA sequence that fully encodes its reaction history suggests its utility for the translation of DNA sequences into high-complexity synthetic libraries suitable for in vitro selection

Exploring Mn-Doped ZnS Quantum Dots for the Room-Temperature Phosphorescence Detection of Enoxacin in Biological Fluids

While most research works focus on the development of quantum dots (QDs)-based fluorescence sensors, much less attention is paid to the phosphorescence properties of QDs and their potential for phosphorescence detection. In this work, the phosphorescence property of Mn-doped ZnS QDs is explored to develop a novel room-temperature phosphorescence (RTP) method for the facile, rapid, cost-effective, sensitive, and selective detection of enoxacin in biological fluids. The Mn-doped ZnS QDs-based RTP method reported here does not need the use of deoxidants and other inducers and allows the detection of enoxacin in biological fluids without interference from autofluorescence and the scattering light of the matrix. The Mn-doped ZnS QDs offer excellent selectivity for detecting enoxacin in the presence of the main relevant metal ions in biological fluids, biomolecules, and other kinds of antibiotics. Quenching of the phosphorescence emission due to the addition of enoxacin at 1.0 µM is unaffected by 5000-fold excesses of Na+ and 10000-fold excesses of K+, Mg2+, and Ca2+. Amino acids such as tryptophan, histidine, and l-cysteine at 1000-fold concentration of enoxacin do not affect the detection of enoxacin. Glucose does not affect the detection at 10000-fold concentration of enoxacin. Typical coadministers (mainly other types of antibiotics) such as ceftezole, cefoperazone, oxacillin, and kalii dehydrographolidi succinas are permitted at 50-, 10-, 100-, and 50-fold excesses, respectively, without interference with the detection of enoxacin. The precision for 11 replicate detections of 0.4 µM enoxacin is 1.8% (RSD). The detection limit for enoxacin is 58.6 nM. The recovery of spiked enoxacin in human urine and serum samples ranges from 94 to 104%. The developed Mn-doped ZnS QDs-based RTP method is employed to monitor the time-dependent concentration of enoxacin in urine from a healthy volunteer after the oral medication of enoxacin. The investigation provides evidence that doped QDs are promising for RTP detection in further applications

Ultralong Room-Temperature Phosphorescence of Boron Carbon Oxynitride Nanodots Encapsulated in Pyrophosphate in Dry and Wet States for Fingerprint Detection and Information Protection

Room-temperature phosphorescence (RTP) materials have attracted wide interest due to their long lifetime and free from background autofluorescence. Nevertheless, simultaneous activation of stable long-lived RTP emission in both solid and aqueous phases remains a tremendous challenge. Herein, a molten salt method to synthesize boron carbon oxynitride nanodot-based RTP composites (BCNO nanodots@pyrophosphate) was carried out by employing pyrophosphate as the inert shell for BCNO nanodots. The BCNO nanodots@pyrophosphate1 with the average size of 3.69 nm show bright-green RTP because the introduction of phosphorus is beneficial to the intersystem crossing process and increases the RTP emission. What is more, whether in solid or aqueous dispersion, BCNO nanodots@pyrophosphate1 retains good phosphorescent properties with a high phosphorescence quantum yield (29.5% and 18.6%) and a long lifetime (1.39 and 1.29 s), which lasts over 15 s to the naked eye. This is the first report on BCNO nanodots with RTP in aqueous solution. The unique RTP characteristics allow BCNO nanodots@pyrophosphate as a hopeful indicator for detection of latent fingerprints with high contrast and multilevel information protection

I've heard it all before: Perceptual invariance represented by early cortical auditory evoked responses.

Sensitivity to acoustic invariance is critical for establishing stable representations in a shifting world of sound. By recording early auditory cortical responses to complex sounds in human listeners and categorising these responses according to the maintenance or change of stimulus attributes across consecutive presentations, we show that repetition within a constantly varying acoustic context produces enhanced neural responding in auditory cortices

Reflection, transmission and surface susceptibility tensor in two-dimensional materials

In a recent experiment, the out-of-plane surface susceptibility of a single-layer two-dimensional atom crystal in the visible spectrum has been measured. This susceptibility gives a measurable contribution to the reflectivity of two-dimensional materials. Here we provide a complete theoretical description of the reflective properties, considering incoming s and p polarized plane waves at any angle of incidence on the crystal, computing local, reflected and transmitted electromagnetic fields. We finally connect the microscopic polarizability to both the in-plane and the out-of-plane macroscopic surface susceptibilities

I've heard it all before: Perceptual invariance represented by early cortical auditory evoked responses.

Sensitivity to acoustic invariance is critical for establishing stable representations in a shifting world of sound. By recording early auditory cortical responses to complex sounds in human listeners and categorising these responses according to the maintenance or change of stimulus attributes across consecutive presentations, we show that repetition within a constantly varying acoustic context produces enhanced neural responding in auditory cortices

Steric Modifications Tune the Regioselectivity of the Alkane Oxidation Catalyzed by Non-Heme Iron Complexes

Iron complexes with the tetradentate N-donor ligand N,N′-di­(phenylmethyl)-N,N′-bis­(2-pyridinylmethyl)-1,2-cyclohexanediamine (bbpc) are reported. Despite the benzyl groups present on the amines, the iron compounds catalyze the oxygenation of cyclohexane to an extent similar to those employing less sterically encumbered ligands. The catalytic activity is strongly dependent on the counterion, with the highest activity and the strongest preference for alkane hydroxylation correlating to the most weakly coordinating anion, SbF6–. The selectivity for the alcohol product over the ketone is amplified when acetic acid is present as an additive. When hydrocarbon substrates with both secondary and tertiary carbons are oxidized by H2O2, the catalyst directs oxidation toward the secondary carbons to a greater degree than other previously reported iron-containing homogeneous catalysts

DNA-Templated Fabrication of Two-Dimensional Metallic Nanostructures by Thermal Evaporation Coating

A biotemplating strategy for fabrication of metallic nanoparticle arrays has been developed. The templates are self-assembled DNA nanostructures, which dictate nanoparticle synthesis in the gas−solid phase (during thermal evaporation)

Steric Modifications Tune the Regioselectivity of the Alkane Oxidation Catalyzed by Non-Heme Iron Complexes

Iron complexes with the tetradentate N-donor ligand N,N′-di­(phenylmethyl)-N,N′-bis­(2-pyridinylmethyl)-1,2-cyclohexanediamine (bbpc) are reported. Despite the benzyl groups present on the amines, the iron compounds catalyze the oxygenation of cyclohexane to an extent similar to those employing less sterically encumbered ligands. The catalytic activity is strongly dependent on the counterion, with the highest activity and the strongest preference for alkane hydroxylation correlating to the most weakly coordinating anion, SbF6–. The selectivity for the alcohol product over the ketone is amplified when acetic acid is present as an additive. When hydrocarbon substrates with both secondary and tertiary carbons are oxidized by H2O2, the catalyst directs oxidation toward the secondary carbons to a greater degree than other previously reported iron-containing homogeneous catalysts