Catalytic Asymmetric Allylation of Prochiral Nucleophiles, α-Acetamido-β-ketoesters

Catalytic Asymmetric Allylation of Prochiral Nucleophiles, α-Acetamido-β-ketoester

Solid-Phase Synthesis and Asymmetric Reactions of Polymer-Supported Highly Enantioenriched Allylsilanes

Solid-Phase Synthesis and Asymmetric Reactions of Polymer-Supported Highly Enantioenriched Allylsilane

Enantioselective Construction of Quaternary α-Carbon Centers on α-Amino Phosphonates via Catalytic Asymmetric Allylation

Asymmetric allylation of α-acetamido β-keto phosphonates was promoted, in the presence of potassium tert-butoxide as a base, by a palladium catalyst prepared from [Pd(π-allyl)(cod)]BF4 and (R)-BINAP and gave the corresponding α-alkyl α-amino phosphonic acid derivatives with 65−88% ee. Diastereoselective reduction of the carbonyl group in the product was accomplished by NaBH4 or Bu4NBH4. The diastereoselection in the reduction was reversed by choice of solvent

Catalytic Asymmetric Synthesis of β-Hydroxy-α-amino Acids: Highly Enantioselective Hydrogenation of β-Oxy-α-acetamidoacrylates

Catalytic Asymmetric Synthesis of β-Hydroxy-α-amino Acids:  Highly Enantioselective Hydrogenation of β-Oxy-α-acetamidoacrylate

<i>β</i>-Borylallylsilanes as a New Tool for Convenient Synthesis of Alkenylboranes

β-Borylallylsilanes as a New Tool for Convenient Synthesis of Alkenylborane

Stereoselective Cyclization of Highly Enantioenriched Allylsilanes with Aldehydes via Acetal Formation: New Asymmetric Access to Tetrahydropyrans and Piperidines

Stereoselective Cyclization of Highly Enantioenriched Allylsilanes with Aldehydes via Acetal Formation:  New Asymmetric Access to Tetrahydropyrans and Piperidine

Stereoselective Synthesis of Isomeric Functionalized 1,3-Dienes from Cyclobutenones

Stereoselective Synthesis of Isomeric Functionalized 1,3-Dienes from Cyclobutenone

Palladium-Catalyzed Addition of Arylboronic Acids to Aldehydes

Arylboronic acids react with aldehydes in the presence of a base and a catalytic amount of a palladium(0) complex with chloroform, affording the corresponding secondary alcohols in good yields. General palladium complexes have no catalytic activity without chloroform. Chloroform is essential for this reaction, and palladium complex that was prepared from Pd(PPh3)4 with CHCl3 showed good catalytic acitivty as well

Stereoselective Cyclization of Highly Enantioenriched Allylsilanes with Aldehydes via Acetal Formation: New Asymmetric Access to Tetrahydropyrans and Piperidines

Stereoselective Cyclization of Highly Enantioenriched Allylsilanes with Aldehydes via Acetal Formation:  New Asymmetric Access to Tetrahydropyrans and Piperidine

Directed Intermolecular [4 + 2] Cycloaddition of Unactivated 1,3-Diene Substrates with High Regio- and Stereoselectivities

Directed Intermolecular [4 + 2] Cycloaddition of Unactivated 1,3-Diene Substrates with High Regio- and Stereoselectivitie