6,225 research outputs found
Electromagnetic wave propagating along a space curve
Using the thin-layer approach, we derive the effective equation for the
electromagnetic wave propagating along a space curve. We find intrinsic
spin-orbit, extrinsic spin-orbit and extrinsic orbital angular momentum and
intrinsic orbital angular momentum couplings induced by torsion, which can lead
to geometric phase, spin and orbital Hall effects. And we show the helicity
inversion induced by curvature that can convert the right-handed circularly
polarized electromagnetic wave into left-handed polarized one, vice verse.
Finally, we demonstrate that the gauge invariance of the effective dynamics is
protected by the geometrically induced gauge potential
Policies and Practices of Professional Development in China: What do Early Childhood Teachers Think?
This paper focuses on early childhood teachersā professional development in China. It reports a study which aims to elicit twelve in-service early childhood teachersā perspectives of the values and issues of professional development policies and the learning opportunities they experienced. Two themes arising from the study are addressed, namely the teachersā positive responses to the government aspirations for enhancing teaching in early childhood education, and the complexities of the organizational and role structures of the early childhood community in ChangChun where the study took place. An important aspect of the teachersā perspectives of their professional development, which connects up to the early childhood environment in ChangChun, is the view that professional development was oriented to their own employment continuity. Teachersā learning was perceived as a useful means to offset the insecurity of their careers, but not closely related to childrenās learning
Expression patterns of metallothionein, cytochrome P450 1A and vitellogenin genes in western mosquitofish (Gambusia affinis) in response to heavy metals
Progressive decay of Ca2+ homeostasis in the development of diabetic cardiomyopathy
BACKGROUND: Cardiac dysfunction in diabetic cardiomyopathy may be associated with abnormal Ca(2+) homeostasis. This study investigated the effects of alterations in Ca(2+) homeostasis and sarcoplasmic reticulum Ca(2+)-associated proteins on cardiac function in the development of diabetic cardiomyopathy. METHODS: SpragueāDawley rats were divided into 4 groups (nā=ā12, each): a control group, and streptozotocin-induced rat models of diabetes groups, examined after 4, 8, or 12Ā weeks. Evaluations on cardiac structure and function were performed by echocardiography and hemodynamic examinations, respectively. Cardiomyocytes were isolated and spontaneous Ca(2+) spark images were formed by introducing fluorescent dye Fluo-4 and obtained with confocal scanning microscopy. Expressions of Ca(2+)-associated proteins were assessed by Western blotting. RESULTS: Echocardiography and hemodynamic measurements revealed that cardiac dysfunction is associated with the progression of diabetes, which also correlated with a gradual but significant decline in Ca(2+) spark frequency (in the 4-, 8- and 12-week diabetic groups). However, Ca(2+) spark decay time constants increased significantly, relative to the control group. Expressions of ryanodine receptor 2 (RyR2), sarcoplasmic reticulum Ca(2+)-2ATPase (SERCA) and Na(+)/Ca(2+) exchanger (NCX1) were decreased, together with quantitative alterations in Ca(2+)regulatory proteins, FKBP12.6 and phospholamban progressively and respectively in the diabetic rats. CONCLUSIONS: Ca(2+) sparks exhibited a time-dependent decay with progression of diabetic cardiomyopathy, which may partly contribute to cardiac dysfunction. This abnormality may be attributable to alterations in the expressions of some Ca(2+)-associated proteins
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