Correlation coefficients among the study variables.

<p>SS subjective support, OS objective support, SA support availability</p

Socio-demographic characteristics and the scores of depression about study sample (n=2080).

<p>*** p<0.001; ** p<0.01; * p<0.05</p

Results of regression analyses.

<p>Results of regression analyses.</p

<i>N</i>‑Bromoimide/DBU Combination as a New Strategy for Intermolecular Allylic Amination

Allylic amination reactions of alkenes, with an NBP (<i>N</i>-bromophthalimide) or NBS (<i>N</i>-bromosuccinimide)/DBU combination, were developed, in which both internal and external nitrogen nucleophiles can be installed directly. Dual activation of NBS or NBP by DBU leads to more electrophilic bromine and more nucleophilic nitrogen atoms simultaneously. This protocol may provide a novel and complementary access to allylic amination under mild conditions

One-Pot Cascade Leading to Direct α‑Imidation of Ketones by a Combination of <i>N</i>‑Bromosuccinimide and 1,8-Diazabicyclo[5.4.1]undec-7-ene

A one-pot cascade transformation of ketones into α-imidoketones has been developed, in which <i>N</i>-bromosuccinimide (NBS) provides both electrophilic bromine and nucleophilic nitrogen sources, and diazabicyclo[5.4.1]undec-7-ene (DBU) functions as a base and a nucleophilic promoter for the activation of NBS. α-Bromination is supposed as the key step in the process, which takes place between more electrophilic bromide active species and enolates

One-Pot Cascade Leading to Direct α‑Imidation of Ketones by a Combination of <i>N</i>‑Bromosuccinimide and 1,8-Diazabicyclo[5.4.1]undec-7-ene

A one-pot cascade transformation of ketones into α-imidoketones has been developed, in which <i>N</i>-bromosuccinimide (NBS) provides both electrophilic bromine and nucleophilic nitrogen sources, and diazabicyclo[5.4.1]undec-7-ene (DBU) functions as a base and a nucleophilic promoter for the activation of NBS. α-Bromination is supposed as the key step in the process, which takes place between more electrophilic bromide active species and enolates

<i>N</i>‑Bromosuccinimide/1,8-Diazabicyclo[5.4.1]undec-7-ene Combination: β‑Amination of Chalcones via a Tandem Bromoamination/Debromination Sequence

A one-pot cascade transformation of chalcones into β-imidoketones has been developed, in which NBS provides both electrophilic bromine and nucleophilic nitrogen sources, and DBU functions as a nucleophilic reagent to activate NBS to be a more electrophilic bromine species and to further remove the bromine of α-bromoketones. The whole process involves tandem bromoamination and debromination, which represents a unique example of preparing β-aminoketones by the reaction of chalcones with the NBS/DBU combination

Using time-varying quantile regression approaches to model the influence of prenatal and infant exposures on childhood growth

<p>For many applications, it is valuable to assess whether the effects of exposures over time vary by quantiles of the outcome. We have previously shown that quantile methods complement the traditional mean-based analyses, and are useful for studies of body size. Here, we extended previous work to time-varying quantile associations. Using data from over 18,000 children in the U.S. Collaborative Perinatal Project, we investigated the impact of maternal pre-pregnancy body mass index (BMI), maternal pregnancy weight gain, placental weight, and birth weight on childhood body size measured 4 times between 3 months and 7 years, using both parametric and non-parametric time-varying quantile regressions. Using our proposed model assessment tool, we found that non-parametric models fit the childhood growth data better than the parametric approaches. We also observed that quantile analysis resulted in difference inferences than the conditional mean models in three of the four constructs (maternal per-pregancy BMI, maternal weight gain, and placental weight). Overall, these results suggest the utility of applying time-varying quantile models for longitudinal outcome data. They also suggest that in the studies of body size, merely modelling the conditional mean may lead to incomplete summary of the data.</p

Analytical methods examined.

<p>Analytical methods examined.</p

False positive results for “1-step LASSO” and “1 model per HOI” methods.

<p>False positive results for “1-step LASSO” and “1 model per HOI” methods.</p