MOESM1 of Activation of a plasmid-situated type III PKS gene cluster by deletion of a wbl gene in deepsea-derived Streptomyces somaliensis SCSIO ZH66

Additional file 1: Table S1. Anti-MRSA activities of violapyrones (VLPs 1–5). Table S2. Bacteria and plasmids used in this study. Table S3. The primer pairs used for cosmid library screening. Table S4. The primer pairs used for PCR-targeted mutagenesis. Table S5. The primer pairs used for PCR confirmation of the mutants. Table S6. The primer pairs used for qPCR analysis. Figure S1. Inactivation of wblA so . Figure S2. Spectral data of VLP B, 1. Figure S3. Inactivation of pksIII-1. Figure S4. Inactivation of vioA. Figure S5. Inactivation of vioB. Figure S6. Inactivation of orf1. Figure S7. Inactivation of orf(-1-2). Figure S8. Spectral data of VLP J, 3. Figure S9. Spectral data of VLP A, 2. Figure S10. Spectral data of VLP C, 4. Figure S11. Spectral data of VLP H, 5. Figure S12. Phenotypes of the S. somaliensis SCSIO ZH66 strains