Human Resources

Nonprofit organizations must have a sound understanding of human resources management in order to effectively accomplish their mission. This training manual provides users of all experience levels with the fundamentals they need to build a successful human resources strategy for operating a nonprofit support organization for AIDS advocacy, prevention and treatment

Data_Sheet_1_Association of social integration with cognitive function trajectories among Chinese older adults: evidence from the China health and retirement longitudinal study (CHARLS).docx

BackgroundThe prevalence of cognitive impairment among older adults remains high. It has been proven that social integration is related to cognitive function. However, limited research has examined the association of social integration and its different dimensions with cognitive function trajectories of older adults.MethodsThe data were from the China Health and Retirement Longitudinal Study (CHARLS) spanning 2013 (T1) to 2018 (T3). A total of 3,977 older adults were included in the final analysis. Cognitive function was measured with items from an adapted Chinese version of the Mini-Mini-Mental Mental State Examination (MMSE), while the measurement of social integration included three dimensions: economic integration, relational integration and community integration. A group-based trajectory model (GBTM) was used to identify cognitive trajectory groups among participants and an unordered multinomial logistic regression was employed to explore the association of baseline social integration and its three dimensions with cognitive function trajectories.ResultThree cognitive function trajectory groups were identified: low-decline group (24.1%), medium-decline group (44.2%) and high-stable group (31.7%). Comparing to the medium-decline trajectory group, older adults with higher social integration scores were more likely to be in the high-stable trajectory group (OR = 1.087, 95%CI: 1.007 ~ 1.174), while less likely to be in the low-decline group (OR = 0.806, 95%CI: 0.736 ~ 0.882). Among the different dimensions of social integration, older adults with higher community integration scores were more likely to be in the high-stable trajectory group (OR = 1.222, 95%CI: 1.026 ~ 1.456); Older adults with higher relational integration scores were less likely to be in the low-decline trajectory group (OR = 0.816, 95%CI: 0.734 ~ 0.906). The economic integration was not found to correlate with the cognitive function trajectories. Stratified analyses revealed that the association between community integration and cognitive trajectories was only significant among older adults aged 60 to 69, and the association between relational integration and cognitive trajectories was only significant among older adults who was agricultural household registration.ConclusionThe developmental trajectories of cognitive function among Chinese older adults are heterogeneous. Social integration is significantly related to the trajectories of cognitive function in Chinese older adults. Measures should be taken to promote social integration of Chinese older adults to reduce the decline of cognitive function.</p

Rhododendron weyrichii Maxim.

原著和名: オンツツジ科名: ツツジ科 = Ericaceae採集地: 高知県 高知市 一宮 (土佐 高知市 一宮)採集日: 1982/4/17採集者: 萩庭丈壽整理番号: JH015511国立科学博物館整理番号: TNS-VS-96551

Serum anti-Aβ42 antibody titers.

<p>The results are presented as the mean titer values. * P<0.05, ** P<0.01, versus mice of control group.</p

Four oligonucleotides for the construction of the Aβ42 gene.

<p>The italics in AD-F1 and AD-R1 indicate BamHI and EcoRI restriction endonuclease sites, respectively.</p><p>Four oligonucleotides for the construction of the Aβ42 gene.</p

Annulus crossing index during the probe trial after the last training trial on the 6^th day.

<p>* P<0.05, versus mice of control group.</p

Immunostaining of B6C3-Tg mouse brains.

<p>Left, frontal lobe (Bar  = 100 µm); middle, hippocampus (Bar  = 100 µm); right, cortex (Bar  = 20 µm).</p

Schematic structure(A), restriction enzyme digestion and PCR identification(B) of recombinant plasmid pBacPAK₈-CTB-Aβ42.

<p>(<b>A</b>) LB, left border; AcMNPV, <i>Autographa Californica</i> Nuclear Polyhedrosis Virus; Ph-Pro, AcMNPV polyhedrin promoter; L, linker peptide (GPGP); poly A⁺, polyadenylation signal; RB, right border. (<b>B</b>) M, DNA marker DL 2000 (TakaRa); lane 1, recombinant plasmid digested with <i>Bam</i>HI and <i>Xho</i> I; lane 2, recombinant plasmid digested with <i>Bam</i>HI; lane 3, recombinant plasmid digested with <i>Xho</i> I; lane 4, PCR amplification of recombinant plasmid.</p

Learning curves showing the average latency (mean ± SE) to find the platform (days 1–5).

<p>Learning curves showing the average latency (mean ± SE) to find the platform (days 1–5).</p

Quantitative analysis of protein production levels in silkworm pupae.

<p>Data are presented as the mean concentrations.</p