6 research outputs found

    DataSheet1_Immobilized Fe3O4-Polydopamine-Thermomyces lanuginosus Lipase-Catalyzed Acylation of Flavonoid Glycosides and Their Analogs: An Improved Insight Into Enzymic Substrate Recognition.PDF

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    The conversion of flavonoid glycosides and their analogs to their lipophilic ester derivatives was developed by nanobiocatalysts from immobilizing Thermomyces lanuginosus lipase (TLL) on polydopamine-functionalized magnetic Fe3O4 nanoparticles (Fe3O4-PDA-TLL). The behavior investigation revealed that Fe3O4-PDA-TLL exhibits a preference for long chain length fatty acids (i.e., C10 to C14) with higher reaction rates of 12.6–13.9 mM/h. Regarding the substrate specificity, Fe3O4-PDA-TLL showed good substrate spectrum and favorably functionalized the primary OH groups, suggesting that the steric hindrances impeded the secondary or phenolic hydroxyl groups of substrates into the bonding site of the active region of TLL to afford the product.</p

    Additional file 2: of Long non-coding RNA HOTAIR polymorphism and susceptibility to cancer: an updated meta-analysis

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    Figure S1. Sensitivity analyses for HOTAIR polymorphisms and cancer risk in heterozygous model. (A) rs920778, (B) rs4759314, (C) rs7958904, (D) rs1899663, (E) rs874945, and (F) rs12826786. (JPEG 754 kb
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