10 research outputs found
Visualization1.avi
A video of 10 high-speed frames with depth map for Fig. 3 in the main paper.
Reconstruction of a backward-moving ball
Visualization2.avi
An 800fps 3D video is reconstructed from 80fps measurements shown in Fig.4 in the main paper
Visualization 1: High-speed compressive range imaging based on active illumination
Reconstructed high-speed 3D video Originally published in Optics Express on 03 October 2016 (oe-24-20-22836
Highly Iso-Selective and Active Catalysts of Sodium and Potassium Monophenoxides Capped by a Crown Ether for the Ring-Opening Polymerization of <i>rac</i>-Lactide
Sodium
and potassium complexes supported by a bulky monophenoxy with one
xanthenyl group at the ortho-position and 18-crown-6 or 15-crown-5
as an auxiliary ligand were synthesized and characterized. These complexes
are highly iso-selective and active catalysts for the controlled ring-opening
polymerization of <i>rac</i>-lactide. The best isotacticity
(<i>P</i><sub>m</sub>) achieved was 0.86, which is the highest
iso-selectivity reported to date for an alkali-metal complex. In addition,
the corresponding polymer exhibited a high <i>T</i><sub>m</sub> of 182 °C. Furthermore, the polymerization looks like
an anti-Arrhenius reaction, which is slower at high temperatures than
at low temperatures
Alkali-Metal Monophenolates with a Sandwich-Type Catalytic Center as Catalysts for Highly Isoselective Polymerization of <i>rac</i>-Lactide
Highly
isoselective ring-opening polymerization (ROP) of <i>rac</i>-lactide is a challenge for sodium and potassium complexes
under mild conditions. In this work, three sodium and potassium complexes
with a sandwich-type catalytic center are highly active catalysts
for the polymerization of <i>rac</i>-lactide and show high
isoselectivities with <i>P</i><sub><i>m</i></sub> values of 0.72–0.82. The best isoselectivity of <i>P</i><sub><i>m</i></sub> = 0.82 is the highest value for alkali-metal
complexes under mild conditions. The molecular weights of the obtained
PLA are close to the theoretical values, and the molecular weight
distributions are narrow
Alternating Sequence Controlled Copolymer Synthesis of α‑Hydroxy Acids via Syndioselective Ring-Opening Polymerization of <i>O</i>‑Carboxyanhydrides Using Zirconium/Hafnium Alkoxide Initiators
The ring-opening
polymerization (ROP) of <i>O</i>-carboxyanhydrides
(OCAs) can give diverse polyÂ(α-hydroxy acid)Âs (PAHAs) with different
functional groups because of easy modification of the side group of
OCAs, which can extend applications of PAHAs widely. The stereoselective
polymerization of <i>O</i>-carboxyanhydrides and further
sequence controlled alternating copolymerization of OCAs were still
big challenges until now for lack of suitable catalysts/initiators.
In this work, a highly syndioselective ROP of OCAs system as the first
stereoselective example in this area is reported using zirconium/hafnium
alkoxides as initiators with the highest <i>P</i><sub>r</sub> value up to 0.95. Furthermore, these initiators were successfully
applied in the precisely alternating sequence controlled copolymerization
of PheOCA and TyrÂ(Bn)ÂOCA, and alternating copolymerization of LacOCA
and PheOCA was also achieved
Stereoselective Alkali-Metal Catalysts for Highly Isotactic Poly(<i>rac</i>-lactide) Synthesis
A high degree of chain end control
in the isoselective ring-opening polymerization (ROP) of <i>rac-</i>lactide is a challenging research goal. In this work, eight highly
active sodium and potassium phenolates as highly isoselective catalysts
for the ROP of <i>rac-</i>lactide are reported. The best
isoselectivity value of <i>P</i><sub>m</sub> = 0.94 is achieved.
The isoselective mechanism is chain-end control through the analysis
of the stereoerrors in the microstructure of a final polymer; thus,
isotactic multiblock structure polymers are obtained, and the highest
melt point can reach 192.5 °C. The donating group in phenolate
can clearly accelerate the ROP reaction, potassium complexes are more
active than the analogous sodium complexes, and the big spacial hindrance
of the ligand can decrease the activity. The high isoselectivities
of these complexes mostly result from their sandwich structure constructed
by the plane of the crown and the plane of the anthryl group
Iso-Selective Ring-Opening Polymerization of <i>rac</i>-Lactide Catalyzed by Crown Ether Complexes of Sodium and Potassium Naphthalenolates
Two crown ether complexes of sodium
and potassium naphthalenolates
were synthesized and entirely characterized. The two complexes can
iso-selectively catalyze the ring-opening polymerization (ROP) of <i>rac</i>-lactide at room temperature and afford polylactides
with desired molecular weights and narrow PDIs; the best isotacticity
(<i>P</i><sub>m</sub>) achieved was 0.73
Data_Sheet_1_Dcf1 Deficiency Attenuates the Role of Activated Microglia During Neuroinflammation.pdf
<p>Microglia serve as the principal immune cells and play crucial roles in the central nervous system, responding to neuroinflammation via migration and the execution of phagocytosis. Dendritic cell-derived factor 1 (Dcf1) is known to play an important role in neural stem cell differentiation, glioma apoptosis, dendritic spine formation, and Alzheimer’s disease (AD), nevertheless, the involvement of the Dcf1 gene in the brain immune response has not yet been reported. In the present paper, the RNA-sequencing and function enrichment analysis suggested that the majority of the down-regulated genes in Dcf1<sup>-/-</sup> (Dcf1-KO) mice are immune-related. In vivo experiments showed that Dcf1 deletion produced profound effects on microglial function, increased the expression of microglial activation markers, such as ionized calcium binding adaptor molecule 1 (Iba1), Cluster of Differentiation 68 (CD68) and translocator protein (TSPO), as well as certain proinflammatory cytokines (Cxcl1, Ccl7, and IL17D), but decreased the migratory and phagocytic abilities of microglial cells, and reduced the expression levels of some other proinflammatory cytokines (Cox-2, IL-1β, IL-6, TNF-α, and Csf1) in the mouse hippocampus. Furthermore, in vitro experiments revealed that in the absence of lipopolysaccharide (LPS), the majority of microglia were ramified and existed in a resting state, with only approximately 10% of cells exhibiting an amoeboid-like morphology, indicative of an activated state. LPS treatment dramatically increased the ratio of activated to resting cells, and Dcf1 downregulation further increased this ratio. These data indicated that Dcf1 deletion mediates neuroinflammation and induces dysfunction of activated microglia, preventing migration and the execution of phagocytosis. These findings support further investigation into the biological mechanisms underlying microglia-related neuroinflammatory diseases, and the role of Dcf1 in the immune response.</p