44 research outputs found

    sj-docx-1-jaf-10.1177_0148558X221100864 – Supplemental material for Customer Concentration and Managerial Bad News Withholding

    No full text
    Supplemental material, sj-docx-1-jaf-10.1177_0148558X221100864 for Customer Concentration and Managerial Bad News Withholding by Yangyang Chen, Gang Hu, Jun Yao and Jingran Zhao in Journal of Accounting, Auditing & Finance</p

    Controllable Porous Nanogrids of Chromium Nitride with Strong Metal–Support Interactions for Achieving Stable Oxygen Reduction Reaction

    No full text
    To facilitate the extensive adoption of proton exchange membrane fuel cells (PEMFCs), it is important to address the issues of electrochemical corrosion and weak interaction with platinum (Pt) caused by the carbon support. Herein, a strong metal–support interaction (SMSI) effect was constructed with Pt nanoparticles loaded in porous chromium nitride (CrN) nanogrids (labeled as Pt/CrN). The porous CrN nanogrids are synthesized via a Maillard nitridation method, and better support size was obtained by controlling the average diameter of CrN nanoparticles by adjusting the proportion of precursors in the oxide preparation. Electrochemical tests establish that Pt/CrN is a stable oxygen reduction reaction catalyst with half-wave potential attenuated by only 4.5 mV after accelerated durability tests, which can be a result of the SMSI effect between Pt and CrN. Moreover, CrN was shown to modulate the ionomer distribution in the catalyst layer (CL). Further investigations have revealed that CrN remains stable up to 1.2 V but degrades significantly above 1.4 V. This work not only broadens the spectrum of Pt-based catalyst support options but also provides insights into the engineering of the SMSI effect. This knowledge will benefit the future design of transition metal nitride for PEMFCs and other technologies

    Additional file 4 of Adalimumab for induction of remission in patients with Crohn's disease: a systematic review and meta-analysis

    No full text
    Additional file 4: Figure S4. Forest plot for failure to achieve clinical response (100-point response) at 4 weeks subgroup by previous TNF-α exposure in ADA and control groups

    Identification of a Key Gene Involved in Branched-Chain Short Fatty Acids Formation in Natto by Transcriptional Analysis and Enzymatic Characterization in <i>Bacillus subtilis</i>

    No full text
    Natto as a fermented soybean product has many health benefits for human due to its rich nutritional and functional components. However, the unpleasant odor of natto, caused by the formation of branched-chain short fatty acids (BCFAs), prohibits the wide acceptance of natto products. This work is to identify the key gene of BCFAs formation and develop the guidance to reduce natto odor. Transcriptional analysis of BCFAs synthesis pathway genes was conducted in two <i>Bacillus subtilis</i> strains with obvious different BCFAs synthesis abilities. The transcriptional levels of <i>bcd</i>, <i>bkdAA</i>, and <i>ptb</i> in <i>B. subtilis</i> H-9 were 2.7-fold, 0.7-fold, and 8.9-fold higher than that of <i>B. subtilis</i> H-4, respectively. Therefore, the <i>ptb</i> gene with the highest transcriptional change was considered as the key gene in BCFAs synthesis. The <i>ptb</i> encoded enzyme Ptb was further characterized by inducible expression in <i>Escherichia coli</i>. The recombinant Ptb protein (about 32 kDa) was verified by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis analysis. The catalysis functions of Ptb were confirmed on substrates of isovaleryl-CoA and isobutyryl-CoA, and the higher catalysis efficiency of Ptb on isovaleryl-CoA explained the higher level of isovaleric acid in natto. The optimal activities of Ptb were observed at 50 °C and pH 8.0, and the enzymatic activity was inhibited by Ca<sup>2+</sup>, Zn<sup>2+</sup>, Ba<sup>2+</sup>, Mn<sup>2+</sup>, Cu<sup>2+</sup>, SDS, and EDTA. Collectively, this study reports a key gene responsible for BCFAs formation in natto fermentation and provides potential strategies to solve the odor problem

    Additional file 3 of Adalimumab for induction of remission in patients with Crohn's disease: a systematic review and meta-analysis

    No full text
    Additional file 3: Figure S3. Forest plot for failure to achieve clinical response (70-point response) at 4 weeks subgroup by previous TNF-α exposure in ADA and control groups

    Additional file 1 of Adalimumab for induction of remission in patients with Crohn's disease: a systematic review and meta-analysis

    No full text
    Additional file 1: Figure S1. Forest plot for failure to achieve clinical remission at 4 weeks subgroup by previous TNF-α exposure in ADA and control groups
    corecore