30,208 research outputs found

    The Development of Mobile Short Video Communication in the Context of the Mobile Internet

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    In the context of the mobile Internet, continuously upgraded media and increasing numbers of terminal devices has enabled information communication to become instant and abundant. The lifestyle of the public has also changed with the evolution of the Internet. The public’s growing enthusiasm for watching short videos on smart phones are one example. This paper discusses changes in the communication environment, namely the concept and development of mobile short videos. Application of Lasswell’s “5W” model to mobile short video communication, is used to analyze this form of communication, using Meipai, a Chinese mobile short video application, as a case study. Suggestions for potential development in this area are also considered

    Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis

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    Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata. The homologues connect via axial elements and numerous transverse filaments to form the synaptonemal complex. The synaptonemal complex is a critical component for chromosome pairing, segregation, and recombination. We previously identified a novel germ cell-specific HORMA domain encoding gene, Hormad1, a member of the synaptonemal complex and a mammalian counterpart to the yeast meiotic HORMA domain protein Hop1. Hormad1 is essential for mammalian gametogenesis as knockout male and female mice are infertile. Hormad1 deficient (Hormad1-/-) testes exhibit meiotic arrest in the early pachytene stage, and synaptonemal complexes cannot be visualized by electron microscopy. Hormad1 deficiency does not affect localization of other synaptonemal complex proteins, SYCP2 and SYCP3, but disrupts homologous chromosome pairing. Double stranded break formation and early recombination events are disrupted in Hormad1-/- testes and ovaries as shown by the drastic decrease in the γH2AX, DMC1, RAD51, and RPA foci. HORMAD1 co-localizes with cH2AX to the sex body during pachytene. BRCA1, ATR, and γH2AX co-localize to the sex body and participate in meiotic sex chromosome inactivation and transcriptional silencing. Hormad1 deficiency abolishes γH2AX, ATR, and BRCA1 localization to the sex chromosomes and causes transcriptional de-repression on the X chromosome. Unlike testes, Hormad1-/- ovaries have seemingly normal ovarian folliculogenesis after puberty. However, embryos generated from Hormad1-/- oocytes are hyper- and hypodiploid at the 2 cell and 8 cell stage, and they arrest at the blastocyst stage. HORMAD1 is therefore a critical component of the synaptonemal complex that affects synapsis, recombination, and meiotic sex chromosome inactivation and transcriptional silencing. © 2010 Shin et al

    Distribution of user-perceived usefulness of four presentation styles of opinion summarization

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    In this study, four opinion summarization styles were compared under an experimental environment. Thirty four participants sorted thirty two cards into five usefulness categories. Every eight cards belong to one presentation style. It was found that the users spent the shortest time on cards in “not at all useful” category. The time of viewing “extremely useful” cards was also shorter than that of “somewhat useful”, “useful”, and “very useful” cards. This result can be explained with the components of the usefulness categories. Tag clouds and Aspect oriented sentiments needed less time to view. They are the major styles in “not at all useful” and “extremely useful”. Paragraph summaries and Group samples requested more time and they took at least 50% in “somewhat useful”, “useful”, and “very useful”. The findings are consistent with our previous results