Reinvestigation of aminoacyl-TRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex

10.1371/journal.pone.0081734PLoS ONE812-POLN

Zero-Permutation Jet-Parton Assignment using a Self-Attention Network

In high-energy particle physics events it can be useful to find the jets correlated with the decay of intermediate states, for example the three jets produced by the hadronic decay of the top quark. Typically, a goodness-of-association measure, such as a $\chi^2$ related to the mass of the associated jets, is constructed, and the best jet combination is found by minimising this $\chi^2$. As this process suffers from combinatorial explosion with the number of jets, the number of permutations is limited by using only the $n$ highest $p_T$ jets. The self-attention block is a neural network unit used for the machine translation problem, which can highlight relationships between any number of inputs in a single iteration without permutations. In this paper, we introduce the self-attention for jet assignment (SaJa) network. SaJa can take any number of jets for input, and outputs probabilities of jet-parton assignment for all jets in a single step. We apply SaJa to find jet-parton assignments of fully-hadronic $t\bar{t}$ events to test the performance.Comment: Code available from https://github.com/CPLUOS/SaJ

Prediction of subcellular localization of proteins using pairwise sequence alignment and support vector machine

Predicting the destination of a protein in a cell is important for annotating the function of the protein. Recent advances have allowed us to develop more accurate methods for predicting the subcellular localization of proteins. One of the most important factors for improving the accuracy of these methods is related to the introduction of new useful features for protein sequences. In this paper we present a new method for extracting appropriate features from the sequence data by computing pairwise sequence alignment scores. As a classifier, support vector machine (SVM) is used. The overall prediction accuracy evaluated by the jackknife validation technique reached 94.70% for the eukaryotic non-plant data set and 92.10% for the eukaryotic plant data set, which is the highest prediction accuracy among the methods reported so far with such data sets. Our experimental results confirm that our feature extraction method based on pairwise sequence alignment is useful for this classification problem

Relational Proxy Loss for Audio-Text based Keyword Spotting

In recent years, there has been an increasing focus on user convenience, leading to increased interest in text-based keyword enrollment systems for keyword spotting (KWS). Since the system utilizes text input during the enrollment phase and audio input during actual usage, we call this task audio-text based KWS. To enable this task, both acoustic and text encoders are typically trained using deep metric learning loss functions, such as triplet- and proxy-based losses. This study aims to improve existing methods by leveraging the structural relations within acoustic embeddings and within text embeddings. Unlike previous studies that only compare acoustic and text embeddings on a point-to-point basis, our approach focuses on the relational structures within the embedding space by introducing the concept of Relational Proxy Loss (RPL). By incorporating RPL, we demonstrated improved performance on the Wall Street Journal (WSJ) corpus.Comment: 5 pages, 2 figures, Accepted by Interspeech 202

Observation of γγ → ττ in proton-proton collisions and limits on the anomalous electromagnetic moments of the τ lepton

The production of a pair of τ leptons via photon–photon fusion, γγ → ττ, is observed for the f irst time in proton–proton collisions, with a significance of 5.3 standard deviations. This observation is based on a data set recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 138 fb−1. Events with a pair of τ leptons produced via photon–photon fusion are selected by requiring them to be back-to-back in the azimuthal direction and to have a minimum number of charged hadrons associated with their production vertex. The τ leptons are reconstructed in their leptonic and hadronic decay modes. The measured fiducial cross section of γγ → ττ is σfid obs = 12.4+3.8 −3.1 fb. Constraints are set on the contributions to the anomalous magnetic moment (aτ) and electric dipole moments (dτ) of the τ lepton originating from potential effects of new physics on the γττ vertex: aτ = 0.0009+0.0032 −0.0031 and |dτ| < 2.9×10−17ecm (95% confidence level), consistent with the standard model