19 research outputs found

    A spherical lesion with decreased volume and low blood flow.

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    <p>Three months after treatment the spherical lesion's volume decreased significantly, and there is no reinforcement of blood flow at the lesion with strengthening in tissues surrounding the lesion.</p

    Funnel plot of the included studies of oral squamous cell carcinoma risk in HPV16 infection.

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    <p>Funnel plot of the included studies of oral squamous cell carcinoma risk in HPV16 infection.</p

    A spherical lesion with significantly decreased volume and no blood flow.

    No full text
    <p>Six months after treatment there is a significant decrease in the volume of the spherical lesion, with no reinforcement of its blood flow. There is no evident increase in blood flow of tissues surrounding the lesion.</p

    A spherical lesion with enhanced blood flow.

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    <p>Before treatment, a spherical lesion and enhanced blood flow is shown by contrast ultrasound.</p

    Funnel plot of the included studies of oral squamous cell carcinoma risk in HPV infection.

    No full text
    <p>Funnel plot of the included studies of oral squamous cell carcinoma risk in HPV infection.</p

    OTUD5 deubiquitininates p53.

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    <p>(A) In vitro translated p53 was pre-incubated for 90 min with a bacterially expressed MDM2 and subsequently immunoprecipitated with an anti-p53 antibody. Immunoprecipitated p53 was then incubated with in vitro translated OTUD5, followed by western blotting with anti-UB to detect the ubiquitination of p53 and blotted with anti-p53, anti-OTUD5 and anti-MDM2 as loading control. (B) OTUD5 does not affect the auto-ubiquitination of MDM2 in vitro. Immobilized GST–Mdm2 protein was incubated with His-OTUD5, E1, E2 and Ub as indicated. (C,D) The H1299 cells were transfected with the indicated combinations of expression vectors. Cells, 24 h after transfection, were treated with MG132 (5 μM) for 3 h and then lysed. Cell lysates were immunoprecipitated with anti-HA antibody (against HA-p53) and immunoblotted with anti-Myc antibody (against Myc-ubiquitin).</p
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