325 research outputs found
Leben und Zusammenleben der Sprachgruppen in Südtirol: Auswirkungen von Autonomie und Minderheitenschutz auf Schule und Bevölkerung
Effect of TP on Biochemical Indicators. (DOCX 14 kb
Image_1_Development and validation of a web-based predictive model for preoperative diagnosis of localized colorectal cancer and colorectal adenoma.tif
BackgroundLocalized colorectal cancer (LCC) has obscure clinical signs, which are difficult to distinguish from colorectal adenoma (CA). This study aimed to develop and validate a web-based predictive model for preoperative diagnosis of LCC and CA.MethodsWe conducted a retrospective study that included data from 500 patients with LCC and 980 patients with CA who were admitted to Dongyang People’s Hospital between November 2012 and June 2022. Patients were randomly divided into the training (n=1036) and validation (n=444) cohorts. Univariate logistic regression, least absolute shrinkage and selection operator regression, and multivariate logistic regression were used to select the variables for predictive models. The area under the curve (AUC), calibration curve, decision curve analysis (DCA), and clinical impact curve (CIC) were used to evaluate the performance of the model.ResultsThe web-based predictive model was developed, including nine independent risk factors: age, sex, drinking history, white blood cell count, lymphocyte count, red blood cell distribution width, albumin, carcinoembryonic antigen, and fecal occult blood test. The AUC of the prediction model in the training and validation cohorts was 0.910 (0.892–0.929) and 0.894 (0.862–0.925), respectively. The calibration curve showed good consistency between the outcome predicted by the model and the actual diagnosis. DCA and CIC showed that the predictive model had a good clinical application value.ConclusionThis study first developed a web-based preoperative prediction model, which can discriminate LCC from CA and can be used to quantitatively assess the risks and benefits in clinical practice.</p
Brewster-Angle Variable Polarization Spectroscopy of Colloidal Au-Nanospheres and -Nanorods at the Silicon Surface
Colloidal Au-nanospheres and -nanorods were chemically
synthesized from chloroauric acid containing solutions and adsorbed
to hydrogen-terminated p-Si(111) surfaces. A comparative analysis
of the respective plasmon resonance modes, in solution and at the
silicon surface, was carried out by in situ optical transmission and
surface reflection techniques. In solution, the absorbance was determined
by VIS transmission spectroscopy and compared to Mie theory as well
as finite difference time domain calculations. At the p-Si(111) surface,
the reflectance was analyzed for the first time by Brewster-angle
variable polarization spectroscopy (BA-VPS) and discussed in terms
of anisotropic uniaxial thin-film properties. With BA-VPS, the strengths
of parallel and orthogonal electric field components of the incident
wave can be varied relative to the surface plane. Consequently, opposite
changes of transverse and longitudinal resonance strengths are detected
upon gradually incremented light polarization angles. Model considerations
confirm that spherical and elongated particles can thereby be distinguished.
The influence of particle–surface interaction and the dielectric
environment is finally discussed
Bioinspired Synthesis of Hierarchically Porous MoO<sub>2</sub>/Mo<sub>2</sub>C Nanocrystal Decorated N‑Doped Carbon Foam for Lithium–Oxygen Batteries
The lithium oxygen
(Li–O<sub>2</sub>) battery is one of
the most promising technologies among various electrochemical energy
storage systems. The challenge to develop a high-performance Li–O<sub>2</sub> battery lies in exploring an air electrode with optimal porous
structure and high efficient bifunctional electrocatalyst. The present
work demonstrates a bioinspired synthesis route for the preparation
of high performance Li–O<sub>2</sub> air electrode materials
that are made out of N-doped carbon foams decorated with heteronanostructured
MoO<sub>2</sub>/Mo<sub>2</sub>C nanocrystals (MoO<sub>2</sub>/Mo<sub>2</sub>C@3D NCF). Here, recombinant proteins (ELK16-FLAG) facilitated
the self-assembly of metal precursors and provided a carbon source
for Mo<sub>2</sub>C formation. The as-prepared MoO<sub>2</sub>/Mo<sub>2</sub>C@3D NCF showed superior electrocatalytic activity in both
oxygen evolution reaction and oxygen reduction reaction mechanisms
with a high round-trip efficiency of 89.1% (2.77 V/3.11 V) at 100
mA g<sup>–1</sup> as well as exceptional rate performances
and good cyclability in Li–O<sub>2</sub> battery. The desirable
electrochemical performance can be attributed to the unique hierarchical
porous structure of the 3D carbon foam and the intimate contact between
MoO<sub>2</sub> and Mo<sub>2</sub>C nanocrystals. We demonstrate that
the novel, facile, environmentally friendly bioinspired approaches
would open new avenues for the synthesis of 3D nitrogen doped carbon
supported advanced functional materials with excellent electrochemical
performances
Dhak activity in <i>D. salina</i> cells under different salinity stresses.
<p>Columns represent the means of three replicated studies in each sample, with the SD of the means (T test, P<0.05). The significance of the differences between the control (2.0) and test values were tested by using one-way ANOVA. *, P<0.05 vs control.</p
The pathway of glycerol metabolism in <i>Dunaliella</i>.
<p>The pathway of glycerol metabolism in <i>Dunaliella</i>.</p
Feasibility and Safety of Video Endoscopic Inguinal Lymphadenectomy in Vulvar Cancer: A Systematic Review
<div><p>Objective</p><p>To systematically review previous studies and to evaluate the feasibility and safety of video endoscopic inguinal lymphadenectomy (VEIL) in vulvar cancer.</p><p>Methods</p><p>We conducted a comprehensive review of studies published through September 2014 to retrieve all relevant articles. The PubMed, EMBASE, Web of Science, Cochrane Library, Wan Fang Data and Chinese National Knowledge Infrastructure databases were systematically searched for all relevant studies published in English or Chinese through September 2014. Data were abstracted independently by two reviewers, and any differences were resolved by consensus.</p><p>Results</p><p>A total of 9 studies containing 249 VEIL procedures involving 138 patients were reviewed. Of the 249 VEIL procedures, only 1 (0.4%) was converted to an open procedure for suturing because of injury to the femoral vein. The range of operative time was 62 to 110 minutes, and the range of estimated blood loss was 5.5 to 22 ml. The range of the number of harvested lymph nodes was 7.3 to 16. The length of hospital stay varied from 7 to 13.6 days across reports. The incidence of lymph node metastasis was 19.7% (27/138), and the recurrence rate was 4.3% (3/70) within 3 to 41 months of follow-up. One or more short-term complications were documented in 18 of 138 (13.0%) patients. Complications after VEIL were observed in 14 (10.13%) patients and in 15 (6.0%) of the VEIL cases, including major lymphocyst formation in 9 (3.6%), lymphorrhea in 2 (0.8%), inguinal wound infection without wound breakdown in 3 (1.2%) and lymphedema in 1 (0.4%).</p><p>Conclusions</p><p>VEIL appears to be a feasible procedure in the management of vulvar cancer. There may be potential benefits that result in lower morbidity compared to traditional methods, but this has yet to be objectively proven.</p></div
NADPH-specific Dhar activity in <i>D. salina</i> cells under different salinity stresses.
<p>(A): Cells grown chronically at various salinities; (B): Cells treated by hyperosmotic or hypoosmotic shock. Columns represent the means of three replicated studies in each sample, with the SD of the means (T test, P<0.05). The significance of the differences between the control (2.0) and test values were tested by using one-way ANOVA. *, P<0.05 vs control.</p
G3pp activity in <i>D. salina</i> cells under different salinity stresses.
<p>Columns represent the means of three replicated studies in each sample, with the SD of the means (T test, P<0.05). The significance of the differences between the control (2.0) and test values were tested by using one-way ANOVA. *, P<0.05 vs control.</p
(NAD<sup>+</sup>)-dependent G3pdh activity in <i>D. salina</i> cells under different salinity stresses.
<p>(A): Cells grown chronically at various salinities; (B): Cells treated by hyperosmotic or hypoosmotic shock. Columns represent the means of three replicated studies in each sample, with the SD of the means (T test, P<0.01). The significance of the differences between the control (2.0) and test values were tested by using one-way ANOVA. *, P<0.05 vs control.</p
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