Quantitative evaluation for four methods on simulation image.

Quantitative evaluation for four methods on simulation image.</p

Features used in our approach.

Features used in our approach.</p

Description of six real microarray data sets.

Description of six real microarray data sets.</p

Segmentation results of various shape spots.

Segmentation results of various shape spots.</p

Scatter plot of two channel intensities for four methods on image drawn from SMD dataset.

Scatter plot of two channel intensities for four methods on image drawn from SMD dataset.</p

Segmentation results of four methods on microarray images drawn from six data sets.

Segmentation results of four methods on microarray images drawn from six data sets.</p

Gene expression for images in Fig 4 with four different methods.

Gene expression for images in Fig 4 with four different methods.</p

Flowchart of improved clustering-based image segmentation method.

Flowchart of improved clustering-based image segmentation method.</p

Examples of segmentation results on simulation images.

Examples of segmentation results on simulation images.</p

The mean, minimum and maximum background-corrected intensities of four methods for two channels on six datasets.

The mean, minimum and maximum background-corrected intensities of four methods for two channels on six datasets.</p