2,221 research outputs found
Sampling Plans for Control-Inspection Schemes Under Independent and Dependent Sampling Designs With Applications to Photovoltaics
The evaluation of produced items at the time of delivery is, in practice,
usually amended by at least one inspection at later time points. We extend the
methodology of acceptance sampling for variables for arbitrary unknown
distributions when additional sampling infor- mation is available to such
settings. Based on appropriate approximations of the operating characteristic,
we derive new acceptance sampling plans that control the overall operating
characteristic. The results cover the case of independent sampling as well as
the case of dependent sampling. In particular, we study a modified panel
sampling design and the case of spatial batch sampling. The latter is advisable
in photovoltaic field monitoring studies, since it allows to detect and analyze
local clusters of degraded or damaged modules. Some finite sample properties
are examined by a simulation study, focusing on the accuracy of estimation
Real Time Turbulent Video Perfecting by Image Stabilization and Super-Resolution
Image and video quality in Long Range Observation Systems (LOROS) suffer from
atmospheric turbulence that causes small neighbourhoods in image frames to
chaotically move in different directions and substantially hampers visual
analysis of such image and video sequences. The paper presents a real-time
algorithm for perfecting turbulence degraded videos by means of stabilization
and resolution enhancement. The latter is achieved by exploiting the turbulent
motion. The algorithm involves generation of a reference frame and estimation,
for each incoming video frame, of a local image displacement map with respect
to the reference frame; segmentation of the displacement map into two classes:
stationary and moving objects and resolution enhancement of stationary objects,
while preserving real motion. Experiments with synthetic and real-life
sequences have shown that the enhanced videos, generated in real time, exhibit
substantially better resolution and complete stabilization for stationary
objects while retaining real motion.Comment: Submitted to The Seventh IASTED International Conference on
Visualization, Imaging, and Image Processing (VIIP 2007) August, 2007 Palma
de Mallorca, Spai
Top Management Team Diversity: A systematic Review
Empirical research investigating the impact of top management team (TMT)
diversity on executives’ decision making has produced inconclusive results.
To synthesize and aggregate the results on the diversity-performance
link, a meta-regression analysis (MRA) is conducted. It integrates more
than 200 estimates from 53 empirical studies investigating TMT diversity
and its impact on the quality of executives’ decision making as reflected
in corporate performance. The analysis contributes to the literature by
theoretically discussing and empirically examining the effects of TMT diversity
on corporate performance. Our results do not show a link between TMT
diversity and performance but provide evidence for publication bias. Thus,
the findings raise doubts on the impact of TMT diversity on performance
Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region
BACKGROUND: The Dlk1 and Gtl2 genes define a region of mouse chromosome 12 that is subject to genomic imprinting, the parental allele-specific expression of a gene. Although imprinted genes play important roles in growth and development, the mechanisms by which imprinting is established and maintained are poorly understood. Differentially methylated regions (DMRs), which carry methylation on only one parental allele, are involved in imprinting control at many loci. The Dlk1-Gtl2 region contains three known DMRs, the Dlk1 DMR in the 3' region of Dlk1, the intergenic DMR 15 kb upstream of Gtl2, and the Gtl2 DMR at the Gtl2 promoter. Three mouse models are analyzed here that provide new information about the regulation of Dlk1-Gtl2 imprinting. RESULTS: A previously existing insertional mutation (Gtl2lacZ), and a targeted deletion in which the Gtl2 upstream region was replaced by a Neo cassette (Gtl2Δ5'Neo), display partial lethality and dwarfism upon paternal inheritance. Molecular characterization shows that both mutations cause loss of imprinting and changes in expression of the Dlk1, Gtl2 and Meg8/Rian genes. Dlk1 levels are decreased upon paternal inheritance of either mutation, suggesting Dlk1 may be causative for the lethality and dwarfism. Loss of imprinting on the paternal chromosome in both Gtl2lacZ and Gtl2Δ5'Neo mice is accompanied by the loss of paternal-specific Gtl2 DMR methylation, while maternal loss of imprinting suggests a previously unknown regulatory role for the maternal Gtl2 DMR. Unexpectedly, when the Neo gene is excised, Gtl2Δ5' animals are of normal size, imprinting is unchanged and the Gtl2 DMR is properly methylated. The exogenous DNA sequences integrated upstream of Gtl2 are therefore responsible for the growth and imprinting effects. CONCLUSION: These data provide further evidence for the coregulation of the imprinted Dlk1 and Gtl2 genes, and support a role for Dlk1 as an important neonatal growth factor. The ability of the Gtl2lacZ and Gtl2Δ5'Neo mutations to cause long-range changes in imprinting and gene expression suggest that regional imprinting regulatory elements may lie in proximity to the integration site
Application of the gel shift assay to study the affinity and specificity of anti-DNA autoantibodies
We have demonstrated that the gel shift assay, a powerful method to study protein [middle dot] DNA interactions under equilibrium conditions, is both an accurate and precise method to measure the affinity of anti-DNA [middle dot] DNA immune complexes. One difficulty in performing gel shift assays is disruption of protein [middle dot] DNA equilibria during the time needed for complexes to enter the gel matrix. However, we have found that highly cross-linked polyacrylamide gels, which are known to form non-restrictive matrices, do not perturb anti-DNA[middle dot]DNA complexes. Using anti-ssDNA BV04-01 as a model antibody, we find good agreement between the dissociation constants (Kd) measureed in the gel shift assay using a 5.4% polyacrylamide gel cross-linked with 0.6% (bis)acrylamide, and those obtained previously by fluorescence quenching. Because gel shift assays require only nanogram quantities of analyte and can be performed in several hours, it is well suited for a range of anti-DNA binding studies.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31125/1/0000022.pd
Simple Frameshifts in MIS Postoperative Pain Management Significantly Reduce Opiate Prescriptions
Aims for Improvement The intervention aimed to reduce narcotics provided to patients after MIS by reducing number of narcotic prescriptions and amount prescribed by 25% without affecting patientreported pain scores Usage measured in Morphine Equivalent Doses (MED) MED and pain score assessed at 3 time points: post-op day 1 (POD1), discharge (D/C) and follow-up (FU) apt Pre- and Post-intervention cohorts - Month 1 (Pre-intervention): 21 patients and Month 2 (Post-intervention): 30 patient
Nation, Migration, Identity: Learning from the Cross-Strait Context
It has been argued that globalisation, with its flexible landscapes of production, consumption and mobility, has favoured the emergence of new forms of belonging and identity that are not necessarily built on such principles of the nation state. In this paper, we argue that this process is more likely to happen when movements occur between states that are not in conflictual relations with each other. When the relations between two nations are shaped by conflicts, for instance due to disputes about sovereignty over a territory, nationalism may remain a crucial factor shaping identification and belonging of those who move between the two territories. In this paper, by taking the case of migrants moving between the People’s Republic of China and Taiwan, we will shed light on how the issue of “unresolved sovereignty” may eventually lead these actors to reinforce nationalist ideals and identities in their daily narratives and practices, instead of favouring the generation of hybrid identities
Neurohistological basis for the functioning of paired half-centers
No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/49962/1/901010208_ftp.pd
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