136 research outputs found

    EMT of ARPE-19 cells induced by TGF-β1.

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    <p>ARPE-19 cells were grown on glass coverslips for 24 hr, starved for 24 hr, and then incubated for 24 hr, 48 hr, 72 hr with 10 ng/ml TGF-β1. Compared with control cells (A, E, I, M, Q), stimulated cells displayed an altered mesenchymal morphology by phase-contrast microscopy (B, C, D), with decreasing expression of E-cadherin (F, G, H) and ZO-1 (J, K, L) and an increasing expression of fibronectin (N, O, P) and α-SMA (R, S, T) by immunofluorescence microscopy. The green signal represents the staining of corresponding protein, and the red signal represents the nuclei staining by DAPI. Original magnifications 100× (A–D); 400× (E–T).</p

    Demographic and clinical characteristics of 109 patients with diabetic retinopathy.

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    <p>DR, diabetic retinopathy; SD, standard deviation; CI, confidence interval; BCVA, best-corrected visual acuity; DM, diabetes mellitus; NPDR, non-proliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; DME, diabetic macular edema.</p><p>Demographic and clinical characteristics of 109 patients with diabetic retinopathy.</p

    Predictors of time trade-off and rating scale utility values from diabetic retinopathy patients and ophthalmologists, determined by bivariate analyses.

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    <p>DR, diabetic retinopathy; TTO, time trade-off; RS, rating scale; DME, diabetic macular edema.</p><p>*Pearson correlation coefficients and analysis of variance (ANOVA) were used.</p><p>Predictors of time trade-off and rating scale utility values from diabetic retinopathy patients and ophthalmologists, determined by bivariate analyses.</p

    Comparison of the patients’ and ophthalmologists’ utility values using time trade-off and rating scale methods.

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    <p>TTO, time trade-off; RS, rating scale.</p><p>*t and <i>p</i> value comparing patients’ and ophthalmologists’ utility values within each visual group using the paired two-tailed Student’s t test.</p><p>Comparison of the patients’ and ophthalmologists’ utility values using time trade-off and rating scale methods.</p

    The effects of PAPep on protein leakage and cellular infiltration into the aqueous humor during EIU.

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    <p>The rats were treated with vehicle (PBS), PAPS (10 µg/eye), PAPep (1, 5, 10 µg/eye) or dexamethasone (10 µg/eye) 1 h before LPS (200 µg) injection. Protein levels (A) and cell count (B) were assessed in the AqH 24 h after EIU. Data are expressed as mean±SD (n = 8 per group). ##, P<0.01 compared with control group; **, P<0.01 compared with vehicle-treated group. Dex, dexamethasone.</p

    Preoperative socieodemographic, clinical, CLVQOL and self-rated satisfaction data, and primary surgery data of 140 eligible RRD patients<sup>*</sup>.

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    <p>*CLVQOL: Chinese-version Low Vision Quality of Life Questionnaire, RRD: rhegmatogenous retinal detachment, BCVA: best corrected visual acuity, SD: standard deviation.</p

    Scatter dot-plots of utility values from diabetic retinopathy patients and ophthalmologists, using the time trade-off method.

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    <p>Scatter dot-plots of utility values from diabetic retinopathy patients and ophthalmologists, using the time trade-off method.</p
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