EFFECT OF MODERATE RUNNING ON SPORTS INJURY REHABILITATION

ABSTRACT Introduction Running has become one of the most popular sports and fitness methods for low cost, convenience, and easy adherence. This has made the characteristics and rules of running-related sports injuries a key research issue in sports medicine and public health. Objective Evaluate the effects of moderate running on sports injuries rehabilitation. Methods This paper uses mathematical statistics to study some groups that have been running for a long time (n=369). The causes of sports injuries analyses and risks are performed by questionnaire. Results Relaxation after exercise is a protective factor for sports injuries. The time of maintenance of the running habit and the previous sport’s history are factors influencing the risk for a sport’s injury. Conclusion Amateur runners have a high rate of running injuries. The knee is the area with the highest injury incidence. Weight-loss running increases the risk of injury. An individually moderate running training plan can reduce the risk of running injuries. Evidence level II; Therapeutic Studies - Investigating the results.</div

Image_3_Effects of Blidingia sp. Extract on Intestinal Inflammation and Microbiota Composition in LPS-Challenged Mice.JPEG

Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water–methanol extract of Blidingia sp. in a mouse model of lipopolysaccharide (LPS)-induced intestinal inflammation. The results revealed that the administration of Blidingia extract significantly alleviated the LPS-induced increase of the inflammatory cytokine content in the serum, as well as latter’s gene expression in the ileum. Moreover, the extract inhibited the phosphorylation of NF-κB and IκBα in LPS-challenged mice. Apart from these changes, the extract also averted intestinal morphology damage(s) and cell apoptosis in mice. Interestingly, the extract also had beneficial effects on the diversity and composition of caecal microbiota in LPS-challenged mice. In conclusion, the results suggested that Blidingia extract had beneficial effects on the recovery of intestinal function by reducing the inflammatory response, improving the maintenance of intestinal morphology, and decreasing cell apoptosis in LPS-induced intestinal inflammation. In addition, the beneficial effects of the extract on caecal microbiota composition may play a role in its anti-inflammatory activity. These results suggested that Blidingia extract could be potentially used in preventing intestinal inflammation.</p

Table_1_Effects of Blidingia sp. Extract on Intestinal Inflammation and Microbiota Composition in LPS-Challenged Mice.DOCX

Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water–methanol extract of Blidingia sp. in a mouse model of lipopolysaccharide (LPS)-induced intestinal inflammation. The results revealed that the administration of Blidingia extract significantly alleviated the LPS-induced increase of the inflammatory cytokine content in the serum, as well as latter’s gene expression in the ileum. Moreover, the extract inhibited the phosphorylation of NF-κB and IκBα in LPS-challenged mice. Apart from these changes, the extract also averted intestinal morphology damage(s) and cell apoptosis in mice. Interestingly, the extract also had beneficial effects on the diversity and composition of caecal microbiota in LPS-challenged mice. In conclusion, the results suggested that Blidingia extract had beneficial effects on the recovery of intestinal function by reducing the inflammatory response, improving the maintenance of intestinal morphology, and decreasing cell apoptosis in LPS-induced intestinal inflammation. In addition, the beneficial effects of the extract on caecal microbiota composition may play a role in its anti-inflammatory activity. These results suggested that Blidingia extract could be potentially used in preventing intestinal inflammation.</p

Image_4_Effects of Blidingia sp. Extract on Intestinal Inflammation and Microbiota Composition in LPS-Challenged Mice.JPEG

Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water–methanol extract of Blidingia sp. in a mouse model of lipopolysaccharide (LPS)-induced intestinal inflammation. The results revealed that the administration of Blidingia extract significantly alleviated the LPS-induced increase of the inflammatory cytokine content in the serum, as well as latter’s gene expression in the ileum. Moreover, the extract inhibited the phosphorylation of NF-κB and IκBα in LPS-challenged mice. Apart from these changes, the extract also averted intestinal morphology damage(s) and cell apoptosis in mice. Interestingly, the extract also had beneficial effects on the diversity and composition of caecal microbiota in LPS-challenged mice. In conclusion, the results suggested that Blidingia extract had beneficial effects on the recovery of intestinal function by reducing the inflammatory response, improving the maintenance of intestinal morphology, and decreasing cell apoptosis in LPS-induced intestinal inflammation. In addition, the beneficial effects of the extract on caecal microbiota composition may play a role in its anti-inflammatory activity. These results suggested that Blidingia extract could be potentially used in preventing intestinal inflammation.</p

Image_2_Effects of Blidingia sp. Extract on Intestinal Inflammation and Microbiota Composition in LPS-Challenged Mice.JPEG

Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water–methanol extract of Blidingia sp. in a mouse model of lipopolysaccharide (LPS)-induced intestinal inflammation. The results revealed that the administration of Blidingia extract significantly alleviated the LPS-induced increase of the inflammatory cytokine content in the serum, as well as latter’s gene expression in the ileum. Moreover, the extract inhibited the phosphorylation of NF-κB and IκBα in LPS-challenged mice. Apart from these changes, the extract also averted intestinal morphology damage(s) and cell apoptosis in mice. Interestingly, the extract also had beneficial effects on the diversity and composition of caecal microbiota in LPS-challenged mice. In conclusion, the results suggested that Blidingia extract had beneficial effects on the recovery of intestinal function by reducing the inflammatory response, improving the maintenance of intestinal morphology, and decreasing cell apoptosis in LPS-induced intestinal inflammation. In addition, the beneficial effects of the extract on caecal microbiota composition may play a role in its anti-inflammatory activity. These results suggested that Blidingia extract could be potentially used in preventing intestinal inflammation.</p

Image_1_Effects of Blidingia sp. Extract on Intestinal Inflammation and Microbiota Composition in LPS-Challenged Mice.JPEG

Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water–methanol extract of Blidingia sp. in a mouse model of lipopolysaccharide (LPS)-induced intestinal inflammation. The results revealed that the administration of Blidingia extract significantly alleviated the LPS-induced increase of the inflammatory cytokine content in the serum, as well as latter’s gene expression in the ileum. Moreover, the extract inhibited the phosphorylation of NF-κB and IκBα in LPS-challenged mice. Apart from these changes, the extract also averted intestinal morphology damage(s) and cell apoptosis in mice. Interestingly, the extract also had beneficial effects on the diversity and composition of caecal microbiota in LPS-challenged mice. In conclusion, the results suggested that Blidingia extract had beneficial effects on the recovery of intestinal function by reducing the inflammatory response, improving the maintenance of intestinal morphology, and decreasing cell apoptosis in LPS-induced intestinal inflammation. In addition, the beneficial effects of the extract on caecal microbiota composition may play a role in its anti-inflammatory activity. These results suggested that Blidingia extract could be potentially used in preventing intestinal inflammation.</p

Estimation and Structural Effect on Physicochemical Properties of Alkylimidazolium-Based Ionic Liquids with Different Anions

Ten kinds of alkylimidazolium-based aprotic ionic liquids (AILs) with hydrogen carbonate, dihydrogen phosphate, and hydrogen sulfate anions were prepared, and methods of elemental analysis, infrared spectroscopy, and proton nuclear magnetic resonance were employed to characterize the ILs, respectively. Properties such as electrical conductivity, density, dynamic viscosity, surface tension, were measured and correlated with thermodynamic and empirical equations over various temperature ranges under ambient conditions. Some significant thermodynamic parameters of the ILs were estimated. The trends of changing with temperature for the dynamic viscosity and the electrical conductivity were described by the Vogel–Fulcher–Tamman equation. The activation energies of dynamic viscosity and electrical conductivity were also calculated. Further, the structures and the energetics of the ILs ions were obtained through combining density functional theory calculations and the COSMO-RS methodology. The structural effects of ion variation on the properties of the ILs were studied

DataSheet_1_Expanding oxygen minimum zones in the northern Indian Ocean predicted by hypoxia-related bacteria.docx

Oxygen minimum zones (OMZs) in the ocean are areas with dissolved oxygen (DO) concentrations below critical thresholds that impact marine ecosystems and biogeochemical cycling. In the northern Indian Ocean (NIO), OMZs exhibit a tendency to expand in mesopelagic waters and contribute significantly to global nitrogen loss and climate change. However, the microbial drivers of OMZ expansion in the NIO remain understudied. Here, we characterized bacterial communities across DO gradients in the NIO using high-throughput 16S rRNA gene sequencing. We found that Marinimicrobia, Chloroflexi, and the SAR324 clade were enriched in both oxygen-deficient and low oxygen mesopelagic waters. Furthermore, Marinimicrobia, Chloroflexi, and the SAR324 clade exhibited a significant negative correlation with DO (P < 0.01), suggesting that they were well-adapted to the oxygen-deficient OMZ habitat. Functional predictions revealed heightened nitrogen metabolism in OMZs, particularly nitrate reduction, suggesting its pivotal role in nitrogen loss. These findings underscore the importance of microbial communities in driving OMZ expansion in the NIO and highlight their implications in global biogeochemical cycles and climate change.</p

MOESM1 of Astragaloside IV attenuates gestational diabetes mellitus via targeting NLRP3 inflammasome in genetic mice

Additional file 1: Table S1. Reproductive parameters in mice administered astragaloside IV

DataSheet_2_Metazoan diversity and community assemblages in sediments across a Western Pacific Trench-Arc-Basin system: insights from eDNA metabarcoding.docx

Trench-arc-basin (TAB) systems are widely distributed in the deep sea, yet our understanding of their biodiversity patterns and community assemblages remains limited. In this study, we collected sediment samples from 22 stations across a Western Pacific TAB system and identified 85 families of marine benthos from 15 phyla by using eDNA metabarcoding with the 18S rRNA gene V4 region. Nematodes were the most dominant metazoan taxa followed by echinoderms, arthropods, and annelids. The highest biodiversity and species specificity were observed at stations located near seamounts. The community assemblages were highly heterogeneous in this TAB system, likely induced by the large geographic barriers and the high habitat heterogeneity. Furthermore, the total organic carbon content and median grain size of the sediment drive the overall community composition, and the water depth exerts a significant influence on species richness and abundance. Our results provide insight into benthos diversity and distribution across a TAB system and data for further comparisons and modeling studies.</p