Construction of Chiral Quaternary Carbon Centers by Pd-Catalyzed Asymmetric Allylic Substitution with <i>P</i>,<i>N</i>-1,1‘-Ferrocene Ligands

A chiral quaternary carbon center on allyl substrates was constructed by Pd-catalyzed allylic alkylation reaction in good to high regio- and enantioselectivities for a wide range of substrates for the first time

Asymmetric Copper-Catalyzed Propargylic Substitution Reaction of Propargylic Acetates with Enamines

Enamines served as carbon-nucleophiles for the first time in the Cu-catalyzed asymmetric propargylic substitution reaction of propargylic acetates, providing corresponding chiral β-ethynyl-substituted ketones in high yields and in good to high enantioselectivity

Construction of Chiral Quaternary Carbon Centers by Pd-Catalyzed Asymmetric Allylic Substitution with <i>P</i>,<i>N</i>-1,1‘-Ferrocene Ligands

A chiral quaternary carbon center on allyl substrates was constructed by Pd-catalyzed allylic alkylation reaction in good to high regio- and enantioselectivities for a wide range of substrates for the first time

Highly Regio- and Enantioselective Palladium-Catalyzed Allylic Alkylation and Amination of Dienyl Esters with 1,1‘-<i>P,N</i>-Ferrocene Ligands

Pd-catalyzed asymmetric allylic alkylation of dienyl acetates 1 and amination of allyl acetates 2 provides the corresponding chiral products in high regio- and enantioselectivities using 1,1‘-P,N-ferrocenes L1a and L2d as ligands, respectively

Highly Regio- and Enantioselective Heck Reaction of <i>N</i>-Methoxycarbonyl-2-pyrroline with Planar Chiral Diphosphine-oxazoline Ferrocenyl Ligands

A series of planar chiral diphosphine-oxazoline ferrocene ligands were effectively applied in the asymmetric arylation of N-methoxycarbonyl-2-pyrroline, and up to 99% ee was observed for the product 3. The regioselectivity of this reaction was strongly affected by the different precursors of the palladium species and the polarity of the solvent

Highly Enantioselective Cu-Catalyzed Conjugate Addition−Elimination of Activated Allylic Acetates with Glycine Derivatives

The reaction of a glycinate Schiff base with the activated alkyl- and aryl-substituted allylic acetates afforded 4-alkylidenylglutamic acid derivatives in high yields and high enantioselectivities by using Cu/P,N-FcPhox as the catalyst

Tributylphosphine: A Remarkable Promoting Reagent for the Ring-Opening Reaction of Aziridines

Tributylphosphine was found to be an effective promoting reagent for ring opening of a variety of aziridines and nucleophiles to produce anti-bifunctional products in good to excellent yield. The study showed that the reaction is initiated through the attack of tributylphosphine as a nucleophile at the carbon atom of the aziridine ring

Unexpected Transfer of Tosyl Group of ArCHNTs-Catalyzed by <i>N</i>-Heterocyclic Carbene

Reactions of N-tosylimines with aziridines and electron-deficient unsaturated compounds in the presence of catalytic amount of NHC afforded unexpected tosyl group transfer products in good to high yields, which represent a new reaction pattern for imines as well as for catalysis of NHC

Tributylphosphine: A Remarkable Promoting Reagent for the Ring-Opening Reaction of Aziridines

Tributylphosphine was found to be an effective promoting reagent for ring opening of a variety of aziridines and nucleophiles to produce anti-bifunctional products in good to excellent yield. The study showed that the reaction is initiated through the attack of tributylphosphine as a nucleophile at the carbon atom of the aziridine ring

Tributylphosphine: A Remarkable Promoting Reagent for the Ring-Opening Reaction of Aziridines

Tributylphosphine was found to be an effective promoting reagent for ring opening of a variety of aziridines and nucleophiles to produce anti-bifunctional products in good to excellent yield. The study showed that the reaction is initiated through the attack of tributylphosphine as a nucleophile at the carbon atom of the aziridine ring