2 research outputs found
Copper-Catalyzed Tandem Reaction of Terminal Alkynes and Sulfonyl Azides for the Assembly of Substituted Aminotriazoles
A simple
combination of CuI/LiO<i>t</i>Bu/DMF enables
the tandem Huisgen [3 + 2] cycloaddition/amidation reaction of terminal
alkynes and sulfonyl azides to 5-sulfamide-1-(<i>N</i>-sulfonyl)-1,2,3-triazoles <b>I</b>, which can undergo an alkylation/desulfonation sequence
to deliver highly substituted aminotriazoles <b>II</b> by one-pot
or one-pot, two-step procedures
Copper-Catalyzed Tandem Reaction of Terminal Alkynes and Sulfonyl Azides for the Assembly of Substituted Aminotriazoles
A simple
combination of CuI/LiO<i>t</i>Bu/DMF enables
the tandem Huisgen [3 + 2] cycloaddition/amidation reaction of terminal
alkynes and sulfonyl azides to 5-sulfamide-1-(<i>N</i>-sulfonyl)-1,2,3-triazoles <b>I</b>, which can undergo an alkylation/desulfonation sequence
to deliver highly substituted aminotriazoles <b>II</b> by one-pot
or one-pot, two-step procedures