Application of Juzen-taiho-to, Hochu-ekki-to, Shofu-san, Oren-gedoku-to and prednisolone initiates histological changes in ear tissues of NC/Nga mice treated repeatedly with mite antigen

<p><b>Copyright information:</b></p><p>Taken from "Kampo Medicines for Mite Antigen-Induced Allergic Dermatitis in NC/Nga Mice"</p><p>Evidence-based Complementary and Alternative Medicine 2005;2(2):191-199.</p><p>Published online 23 Mar 2005</p><p>PMCID:PMC1142189.</p><p>© The Author (2005). Published by Oxford University Press. All rights reserved.</p> Mouse ears were separated 24 h after the fifth antigen application. Tissue sections were stained with hematoxylin–eosin. () no antigen; () control; () Juzen-taiho-to 100 mg/kg; () Juzen-taiho-to 300 mg/kg; () Hochu-ekki-to 100 mg/kg; () Hochu-ekki-to 300 mg/kg; () Shofu-san 100 mg/kg; () Shofu-san 300 mg/kg; () Oren-gedoku-to 100 mg/kg; () Oren-gedoku-to 300 mg/kg; () prednisolone 3 mg/kg

Varied doses of Juzen-taiho-to, Hochu-ekki-to, Shofu-san, Oren-gedoku-to and prednisolone influence ear thickness from repeated painting with mite antigen solution in NC/Nga mice

<p><b>Copyright information:</b></p><p>Taken from "Kampo Medicines for Mite Antigen-Induced Allergic Dermatitis in NC/Nga Mice"</p><p>Evidence-based Complementary and Alternative Medicine 2005;2(2):191-199.</p><p>Published online 23 Mar 2005</p><p>PMCID:PMC1142189.</p><p>© The Author (2005). Published by Oxford University Press. All rights reserved.</p> Ear thickness was measured immediately before, and 1, 4 and 24 h after each antigen application. Results after the first and the second antigen applications were omitted because increased ear thickness and drug effects were negligible. Each value represents the mean ± SEM of 5–8 mice. < 0.05, < 0.01 for Kampo medicine-administered groups by multiple comparison test, < 0.05, < 0.01 for prednisolone-administered group by -test

Mixed results of Juzen-taiho-to, Hochu-ekki-to, Shofu-san, Oren-gedoku-to and prednisolone administration on serum total IgE levels in NC/Nga mice repeatedly treated with mite antigen

<p><b>Copyright information:</b></p><p>Taken from "Kampo Medicines for Mite Antigen-Induced Allergic Dermatitis in NC/Nga Mice"</p><p>Evidence-based Complementary and Alternative Medicine 2005;2(2):191-199.</p><p>Published online 23 Mar 2005</p><p>PMCID:PMC1142189.</p><p>© The Author (2005). Published by Oxford University Press. All rights reserved.</p> Serum samples were obtained 24 h after each antigen application and serum IgE was quantified by enzyme-linked immunosorbent assay. Each value indicates the mean ± SEM of 5–8 mice. < 0.05, < 0.01 for Kampo medicine-administered groups by multiple comparison test; < 0.01 for prednisolone-administered group by -test