The Fermi GBM Gamma-Ray Burst Spectral Catalog: Four Years Of Data

In this catalog we present the updated set of spectral analyses of GRBs detected by the Fermi Gamma-Ray Burst Monitor (GBM) during its first four years of operation. It contains two types of spectra, time-integrated spectral fits and spectral fits at the brightest time bin, from 943 triggered GRBs. Four different spectral models were fitted to the data, resulting in a compendium of more than 7500 spectra. The analysis was performed similarly, but not identically to Goldstein et al. 2012. All 487 GRBs from the first two years have been re-fitted using the same methodology as that of the 456 GRBs in years three and four. We describe, in detail, our procedure and criteria for the analysis, and present the results in the form of parameter distributions both for the observer-frame and rest-frame quantities. The data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center (HEASARC).Comment: Accepted for publication in ApJ

Pan-cancer analysis of whole genomes

Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe

A decision support method for design and operationalization of search and rescue in maritime emergency

Design and operationalization for Search and Rescue (SAR) activities are unstructured and complex multi-criteria decision-making problems, especially for maritime emergency scenario. There is a lack of decision support methods based on intelligent algorithms to shorten the response time and to reduce the loss of life and property. The primary purpose of this paper is to develop a three-stage decision support method to optimize the type and number of resources when making SAR schemes so as to formulate emergency response more efficiently and effectively. First, the main influential factors are identified in Stage 1, including the particulars of environmental indices, search objects and SAR resources. Next, in Stage 2, important variables are defined for generating probability distribution maps, identifying the search areas, and evaluating the objective function in Stage 3. Two intelligent algorithms, the Differential Evolution (DE) and Non-Dominated Sorting Genetic Algorithm-II (NSGA-II), are used to find appropriate SAR schemes and help resources scheduling. Finally, the feasibility and validity of the model are verified by a ship collision example. From the simulation of the SAR task assignment and decision preference analysis, the proposed method can be used for further improvement of SAR design and operationalization.Safety and Security Scienc

Preparation and characterization of poly (urea-formaldehyde) walled dicyclopentadiene microcapsules

Poly (urea-formaldehyde) (PUF) shelled dicyclopentadiene (DCPD) microcapsules were prepared by in-situ polymerization technology for self-healing concrete applications. It’s found, during the process, sodium dodecyl benzene sulfonate (SDBS) behaves better in emulsification of DCPD than other surfactant of sodium lauryl sulfate (SLS) and styrene maleic anhydride copolymer (SMA), and the addition of ammonia chloride (NH4Cl) as PUF curing catalyst accidentally leads to a smooth surface of the microcapsule.Structural EngineeringCivil Engineering and Geoscience

A novel capsule-based selfrecovery system with a chloride ion trigger

Steel is prone to corrosion induced by chloride ions, which is a serious threat to reinforced concrete structures, especially in marine environments. In this work, we report a novel capsule-based selfrecovery system that utilizes chloride ions as a trigger. These capsules, which are functionalized via a smart response to chloride ions, are fabricated using a silver alginate hydrogel that disintegrates upon contact with chloride ions, and thereby releases the activated core materials. The experimental results show that the smart capsules respond to a very low concentration of chloride ions (0.1 wt%). Therefore, we believe that this novel capsule-based self-recovery system will exhibit a promising prospect for self-healing or corrosion inhibition applications.Structural EngineeringCivil Engineering and Geoscience

Length-weight relationships of 21 fishes from the Xiangjiang River, China

This paper provides the length-weight relationships for 21 fish species belonging to four families and 19 genera from the Xiangjiang River, a tributary of the middle Yangtze River in China. Among them, the length-weight relationships for 14 fishes are first-time reports for FishBase, and new maximum total lengths of 13 fishes are also reported

Synthesis of hexagonal mesoporous silicates functionalized with amino groups in the pore channels by a co-condensation approach

Mesoporous silicates functionalized with amino groups in the pore channels have been made by the co-condensation of tetraethoxyl siloxide (TEOS) with precursors of P-Si through a triblock copolymer-templated sol-gel process under acidic conditions. Poly(alkylene oxide) block copolymer (P123) was eluted by ethanol extraction and template molecules were removed by refluxing the materials in a mixture of DMSO and water. The resulting materials were characterized in detail by FT-IR, XRD, TEM and N-2 adsorption, in order to study the effect of the precursors on the mesoscopic order and pore structure. Evidence of amino groups located in the pore channels was shown through variation of pore size and BET surface area after the amino groups were coupled with benzaldehyde, and TEM images of materials after staining with RuO4. Finally, a comparative study of the catalytic performance of materials SBA-Am-10 and SBA-T-10, obtained by two methods, revealed that the catalyst synthesized by our method gave rapid reaction speed and high yields of flavanone by the Claisen-Schmidt condensation of benzaldehyde and 2'-hydroxyacetophenone

Length-weight relationships of three cyprinid fishes from headwater of the Nujiang River, China

Length-weight relationships (LWR) for three cyprinid fish species collected from the headwaters of the Nujiang River in Tibet, China, were determined. The values of parameter b in the LWR equations were estimated as 2.54 for Schizopygopsis thermalis, 3.3 for Ptychobarbus kaznakovi, and 2.74 for Schizothorax nukiangensis, respectively. These are the first LWR records for the three species

885 nm pumped, high efficiency single-frequency Nd:YAG ring laser

We report an efficient single-frequency ring laser pumped directly into emitting level by a fiber-coupled laser diode (FCLD) at 885 nm for the first time. 4.8 W laser at 1064 nm was obtained in a 0.7 at % Nd:YAG with 63% slope efficiency and 51.7% light-light efficiency in absorbed pump power. At the same time, the line width of the longitudinal mode was about 50 MHz, and the beam was nearly diffraction-limited with M2 a parts per thousand 1.07