DataSheet1_How green credit policy shapes financial performance: Evidence from Chinese listed construction energy-saving enterprise.ZIP

This study uses the introduction of the Green Credit Guidelines in 2012 as a quasi-natural experiment. We selected Chinese A-share listed enterprises from 2004 to 2020 as the sample and applied PSM-DID to examine the impact of green credit policy on the performance of construction energy-saving enterprises. The study revealed that: 1) green credit policy has a significant contribution to the performance of construction energy-saving enterprises. In addition, it still holds after the robustness tests (replacing the PSM matching method and adding or subtracting the two methods of control variables) and the placebo test. 2) A positive correlation between the performance of construction energy-saving enterprises and short-term debt. Meanwhile, short-term debt is a mediating variable between green credit policy and the performance of construction energy-saving enterprises. 3) The impact of green credit policy on the performance of non-state-owned (non-SOEs) is more pronounced compared to state-owned (SOEs). This study reveals the micro effects of green credit policy from the perspective of the performance of construction energy-saving enterprises. It not only helps to understand the economic effects of green credit policy, but also provides corresponding insights for the subsequent promotion of green credit policy and construction energy-saving enterprise development systems.</p

Additional file 2 of Genomic profile of Chinese patients with endometrial carcinoma

Supplementary Material

Additional file 1 of Genomic profile of Chinese patients with endometrial carcinoma

Supplementary Material

Protective Role of <i>Helicobacter pylori</i> Infection in Prognosis of Gastric Cancer: Evidence from 2454 Patients with Gastric Cancer

<div><p>Background</p><p>A number of studies have investigated the association between <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection and the prognosis of gastric cancer (GC), with inconsistent and inconclusive results. We performed a meta-analysis to derive a more precise estimation of the association.</p><p>Methodology/Principal Findings</p><p>A systematic search of PubMed, EMBASE, Cochrane and Chinese wanfang databases was performed with the last search updated on February 19, 2013. The hazard ratio (HR) and its 95% confidence interval (95%CI) were used to assess the strength of association. A total of 12 studies including 2454 patients with GC were involved in this meta-analysis. The pooled HR was 0.71 (95%CI: 0.57–0.87; <i>P</i> = 0.001) for OS and 0.60 (95%CI: 0.30–1.18; <i>P</i> = 0.139) for DFS in GC patients, respectively. The protective role of <i>H. pylori</i> infection in the prognosis of GC was also observed among different subgroups stratified by ethnicity, statistical methodology, <i>H. pylori</i> evaluation method and quality assessment. There was no evidence of publication bias.</p><p>Conclusions/Significance</p><p>This meta-analysis suggests a protective role for <i>H. pylori</i> infection in the prognosis of GC. The underlying mechanisms need to be further elucidated, which could provide new therapeutic approaches for GC.</p></div

Publication bias plot for overall survival (A) Begg’s funnel plot (B) Egger’s publication bias plot.

<p>Publication bias plot for overall survival (A) Begg’s funnel plot (B) Egger’s publication bias plot.</p

Forest plot showing the meta-analysis of hazard ratios estimates for overall survival in gastric cancer patients.

<p>Forest plot showing the meta-analysis of hazard ratios estimates for overall survival in gastric cancer patients.</p

Meta-analysis of <i>H. pylori</i> infection with the prognosis of gastric cancer.

<p>Abbreviations: <i>H. pylori</i>, <i>Helicobacter pylori</i>; OS, overall survival; DFS, disease-free survival; PCR, Polymerase chain reaction; HR, hazard ratio; CI, confidence interval; R, random-effects model; F, fixed-effects model.</p>Δ<p>HR = 1 for negative <i>H. pylori</i> status.</p

Dipole Orientation Matters: Longer-Circulating Choline Phosphate than Phosphocholine Liposomes for Enhanced Tumor Targeting

Zwitterionic phosphocholine (PC) liposomes are widely used in drug delivery because of their high biocompatibility and long blood circulation time. We herein report that by flipping the direction of the PC dipole, the resulting choline phosphate (CPe) liposomes have an even longer circulation time, as confirmed at both cellular and animal-model levels. Even when 33% cholesterol was included in the lipid formulation with a poly­(ethylene glycol) layer, the CPe liposome still had a longer blood circulation time. Isothermal titration calorimetry indicates a lack of protein adsorption or PC membrane attachment for the CPe liposomes. This is different from the previously reported adhesion of CP polymers to PC lipid membranes, which may be attributed to the different ways of displaying the CP headgroup. With a longer blood circulation time, the CPe liposomes accumulated in tumors more easily than PC liposomes, which is likely due to the enhanced permeation and retention effect and tumor cell uptake. This study provides key insights into zwitterionic biointerfaces for biomedical, analytical, and materials applications

Sub-Angstrom Gold Nanoparticle/Liposome Interfaces Controlled by Halides

A hallmark of nanoscience is size-dependent and distance-dependent physical properties. Although most previous studies focused on optical properties, which are often tuned at nanometer scale, we herein report on the interaction between halide-capped gold nanoparticles (AuNPs) and phosphocholine (PC) liposomes at the sub-Angstrom level. Halide-capped AuNPs are adsorbed by PC liposomes attributable to van der Waals force. Iodide-capped AuNPs interact much more weakly with the liposomes compared with bromide- and chloride-capped AuNPs, as indicated by a liposome leakage assay and differential scanning calorimetry. This is explained by the slightly larger size of iodide separating the AuNP core more from the liposome surface. Cryo-transmission electron microscopy indicates that the liposomes remain intact when mixed with these halide-capped AuNPs of 13 or 70 nm in diameter. Other even larger ligands, including small thiol compounds, DNA oligonucleotides, proteins, and polymers, fully blocked the interaction, whereas AuNPs dispersed in noninteracting ions, including fluoride, phosphate, perchlorate, nitrate, sulfate, and bicarbonate, are still adsorbed strongly by 1,2-dioleoyl-<i>sn</i>-glycero-3-phosphocholine liposomes. Taken together, halides can be used to control interparticle distances at an extremely small scale with remarkable effects on materials properties, allowing surface probing, biosensor development, and fundamental surface science studies

Additional file 1 of Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics

Supplementary Material 1