Perpendicular Superlattice Growth of Hydrophobic Gold Nanorods on Patterned Silicon Substrates via Evaporation-Induced Self-Assembling

A simple and efficient route has been reported for the perpendicular superlattice self-assembling of hydrophobic gold nanorods (NRs) based on solvent evaporation. The combination of top-down surface patterning and bottom-up material assembling was used for area-selective gold NR superlattices. The superlattice preferably deposited with a perpendicular orientation of gold NRs on the hydrophobic stripe region in the patterned substrate. The superlattice occupied broad areas up to several square millimeters and possessed an uppermost surface of hexagonally close-packed NR monolayers

Effects of Cold Rolling Deformation on Microstructure and Damping Capacity of a Fe-Mn-Cr-Co-Si Alloy

The microstructure evolution of Fe-19Mn-8Cr-1Co-0.2Si (wt.%) alloy and Fe-19Mn (wt.%) alloy during cold rolling and its effect on the damping capacity of the two alloys were investigated. It was shown that the damping capacity of the two alloys was enhanced significantly owing to the deformation-induced ε-martensite and stacking faults. The Fe-19Mn-8Cr-1Co-0.2Si alloy exhibited an accelerated phase transformation from γ-austenite to ε-martensite due to a higher content of retained γ-austenite and larger grain sizes compared with the Fe-19Mn alloy, resulting in a higher maximal increment of damping capacity in this alloy caused by deformation. It was observed that no twinned ε-martensite was generated in the Fe-19Mn-8Cr-1Co-0.2Si alloy during cold rolling, resulting in a remarkable increase in the volume fraction of α'-martensite owing to no impediment to ε → α' transformation, hence the deterioration of damping capacity was slow because the α'-martensite weakened the pinning effect of dislocations on damping sources. In addition, new damping sources were provided due to the occurance of γ-austenite twinning in the Fe-19Mn-8Cr-1Co-0.2Si alloy.</div

Pd-Catalyzed Efficient One-Pot Sequential Cross-Coupling Reactions of Aryl Dihalides

The palladium complex containing N-heterocyclic carbene ligands catalyzes one-pot sequential Heck/Suzuki, Heck/Heck, and Heck/Sonogashira coupling reactions of aryl dihalides to afford unsymmetrically substituted arenes in excellent yields

New Pincer CC′C Complexes of Nickel(II) via Chloronickelation of Alkyne-Bearing N-Heterocyclic Carbenes

Pincer-like nickel complexes of N-heterocyclic carbenes, [Ni(3-chloro-1,4-di(N-aryl-N′-imidazolylidene)but-2-en-2-yl)(CH3CN)](PF6), have been prepared from the transmetalation reactions of the corresponding [Ag2(1,4-di(N-aryl-N′-imidazol-2-ylidene)but-2-yne)2](PF6)2 and [Ni(PPh3)2Cl2]. X-ray diffraction studies show that the distorted square-planar nickel(II) complexes are supported by anionic terdentate ligands with two imidazolylidenes and one vinyl carbon donor originated from chloronickelation of the triple bond. Further studies suggest that the nickel complexes are excellent catalysts for Kumada−Corriu coupling reactions of aryl chlorides even at room temperature

New Pincer CC′C Complexes of Nickel(II) via Chloronickelation of Alkyne-Bearing N-Heterocyclic Carbenes

Pincer-like nickel complexes of N-heterocyclic carbenes, [Ni(3-chloro-1,4-di(N-aryl-N′-imidazolylidene)but-2-en-2-yl)(CH3CN)](PF6), have been prepared from the transmetalation reactions of the corresponding [Ag2(1,4-di(N-aryl-N′-imidazol-2-ylidene)but-2-yne)2](PF6)2 and [Ni(PPh3)2Cl2]. X-ray diffraction studies show that the distorted square-planar nickel(II) complexes are supported by anionic terdentate ligands with two imidazolylidenes and one vinyl carbon donor originated from chloronickelation of the triple bond. Further studies suggest that the nickel complexes are excellent catalysts for Kumada−Corriu coupling reactions of aryl chlorides even at room temperature

Topological Superconductivity Based on Antisymmetric Spin–Orbit Coupling

Topological superconductivity (TSC) has drawn much attention for its fundamental interest and application in quantum computation. An outstanding challenge is the lack of intrinsic TSC materials with a p-wave pairing gap, which has led to the development of an effective p-wave theory of coupling s-wave gap with Rashba spin–orbit coupling (RSOC). However, the RSOC-strict mechanism and materials pose still both fundamental and practical limitations. Here, we generalize this theory to antisymmetric SOC (ASOC). Using k·p perturbation theory, we demonstrate that 2D crystals, with point groups of C2, C4, C6, C2v, C4v, C6v, D2, D4, D6, S4, or D2d, can all facilitate the desired ASOC. Remarkably, this enables us to discover 314 TSC candidates by screening 2D material databases, which are further confirmed by first-principles calculations of Majorana boundary modes and the topological invariant of the superconducting gap. Our work fundamentally enriches TSC theory and greatly expands the classes of TSC materials for experimental exploration

Intramolecular Aminoalkene Hydroamination Catalyzed by Magnesium Complexes Containing Multidentate Phenoxyamine Ligands

The magnesium complexes L2MgiPr (L2 = 4-tert-butyl-6-(triphenylsilyl)-2-[bis((3-(dimethylamino)propyl)amino)methyl]phenoxyl) and L3MgiPr (L3 = 4-tert-butyl-6-(triphenylsilyl)-2-[benzyl((3-(dimethylamino)propyl)amino)methyl]phenoxyl) supported by potentially tetradentate and tridentate triphenylsilyl-substituted phenoxyamine ligands have been prepared and fully characterized. The X-ray crystallographic analysis of L2MgiPr confirmed a monomeric structure in which only one of the amine side arms is bound to the four-coordinate magnesium atom. The free and coordinated side arms in L2MgiPr undergo an exchange process at 25 °C in solution, while the phenoxydiamine complex L3MgiPr, on the other hand, shows no sign of fluxionality. Both complexes, as well as L1MgiPr (L1 = 4,6-di-tert-butyl-2-[bis((3-(dimethylamino)propyl)amino)methyl]phenoxyl), were shown to be competent catalysts in the cyclization of aminoalkenes. L2MgiPr exhibited the best catalytic activity, and both triphenylsilyl-substituted complexes display zero-order rate dependence on substrate concentration and first-order rate dependence on catalyst concentration, whereas the sterically less hindered complex L1MgiPr exhibits second-order rate dependence on substrate concentration. No Schlenk-type ligand redistributions were observed, and the catalytically active magnesium species was stable after prolonged heating to 120 °C, according to an NMR spectroscopic study

Relative spindle abundance and extramuscular nerve trunk length of the thenar and hypothenar muscles.

<p>Relative spindle abundance and extramuscular nerve trunk length of the thenar and hypothenar muscles.</p

Mechanism of Xiaoyao San in treating non-alcoholic fatty liver disease with liver depression and spleen deficiency: based on bioinformatics, metabolomics and <i>in vivo</i> experiments

Xiaoyao san (XYS) plays an important role in treatment of non-alcoholic fatty liver disease (NAFLD) with liver stagnation and spleen deficiency, but its specific mechanism is still unclear. This study aimed to investigate the material basis and mechanism by means of network pharmacology, metabolomics, systems biology and molecular docking methods. On this basis, NAFLD rat model with liver stagnation and spleen deficiency was constructed and XYS was used to intervene, and liver histopathology, biochemical detection, enzyme-linked immunosorbent assay, quantitative PCR assay and western blotting were used to further verify the mechanism. Through the above research methods, network pharmacology study showed that there were 94 targets in total for XYS in the treatment of NAFLD. Metabolomics study showed that NAFLD with liver depression and spleen deficiency had a total of 73 differential metabolites. Systems biology found that PTGS2 and PPARG were the core targets; Quercetin, kaempferol, naringenin, beta-sitosterol and stigmasterol were the core active components; AA, cAMP were the core metabolites. And molecular docking showed that the core active components can act well on the key targets. Animal experiments showed that XYS could improve liver histopathology, increase 5HT and NA, decrease INS and FBG, improve blood lipids and liver function, decrease AA, increase cAMP, down-regulate PTGS2, up-regulate PPARG, and decrease PGE2 and 15d-PGJ2. In conclusion, XYS might treat NAFLD with liver depression and spleen deficiency by down-regulating PTGS2, up-regulating PPARG, reducing AA content, increasing cAMP, improving insulin resistance, affecting glucose and lipid metabolism, inhibiting oxidative stress and inflammatory response. Communicated by Ramaswamy H. Sarma Network pharmacological results found that XYS might treat NAFLD through multiple targets and multiple pathways. Quercetin and kaempferol were main components of XYS in treatment of NAFLD.System biology research results found that PPARG and PTGS2 were the core targets of XYS in the treatment of NAFLD.Metabolomic results suggest that AA and cAMP were differential metabolites of NAFLD.In vivo animal experiments showed that XYS might treat NAFLD by increasing PPARG and decreasing PTGS2, reducing AA and increasing cAMP to regulate glucose metabolism and lipid metabolism. Network pharmacological results found that XYS might treat NAFLD through multiple targets and multiple pathways. Quercetin and kaempferol were main components of XYS in treatment of NAFLD. System biology research results found that PPARG and PTGS2 were the core targets of XYS in the treatment of NAFLD. Metabolomic results suggest that AA and cAMP were differential metabolites of NAFLD. In vivo animal experiments showed that XYS might treat NAFLD by increasing PPARG and decreasing PTGS2, reducing AA and increasing cAMP to regulate glucose metabolism and lipid metabolism.</p

Intramolecular Aminoalkene Hydroamination Catalyzed by Magnesium Complexes Containing Multidentate Phenoxyamine Ligands

The magnesium complexes L2MgiPr (L2 = 4-tert-butyl-6-(triphenylsilyl)-2-[bis((3-(dimethylamino)propyl)amino)methyl]phenoxyl) and L3MgiPr (L3 = 4-tert-butyl-6-(triphenylsilyl)-2-[benzyl((3-(dimethylamino)propyl)amino)methyl]phenoxyl) supported by potentially tetradentate and tridentate triphenylsilyl-substituted phenoxyamine ligands have been prepared and fully characterized. The X-ray crystallographic analysis of L2MgiPr confirmed a monomeric structure in which only one of the amine side arms is bound to the four-coordinate magnesium atom. The free and coordinated side arms in L2MgiPr undergo an exchange process at 25 °C in solution, while the phenoxydiamine complex L3MgiPr, on the other hand, shows no sign of fluxionality. Both complexes, as well as L1MgiPr (L1 = 4,6-di-tert-butyl-2-[bis((3-(dimethylamino)propyl)amino)methyl]phenoxyl), were shown to be competent catalysts in the cyclization of aminoalkenes. L2MgiPr exhibited the best catalytic activity, and both triphenylsilyl-substituted complexes display zero-order rate dependence on substrate concentration and first-order rate dependence on catalyst concentration, whereas the sterically less hindered complex L1MgiPr exhibits second-order rate dependence on substrate concentration. No Schlenk-type ligand redistributions were observed, and the catalytically active magnesium species was stable after prolonged heating to 120 °C, according to an NMR spectroscopic study