Magnetic Chitosan–Iron(III) Hydrogel as a Fast and Reusable Adsorbent for Chromium(VI) Removal

The magnetic chitosan–iron­(III) hydrogel (MCh-Fe) was synthesized and characterized by SEM, TG, XRD, and FT-IR and used to remove toxic chromium­(VI) (Cr^VI) from aqueous solution. The adsorption of Cr^VI onto the MCh-Fe adsorbent was fast and could reach equilibrium in less than 30 min. The adsorption was well described by the pseudo-second-order rate model. The equilibrium isotherm was better matched with the Langmuir model. The adsorption of Cr^VI onto MCh-Fe was an endothermic and spontaneous process. The loading capacity of Cr^VI on the adsorbent remained at a high level even after five cycles, showing that MCh-Fe can be used for repeated Cr^VI removal. Column adsorption results indicated that below 0.5 mg L^–1 Cr^VI was found in the effluent up to about 30 and 350 bed volumes for two wastewaters containing 115.0 and 5.6 mg L^–1 Cr^VI, respectively. The Cr^VI removal mechanism of MCh-Fe was also investigated

Direct Comparison of Electron Transport and Recombination Behaviors of Dye-Sensitized Solar Cells Prepared Using Different Sintering Processes

Flexible dye-sensitized solar cells on plastic substrates have achieved a conversion efficiency of 8.6% with the hot compression technique (<150 °C). However, the value of efficiency is only 70% of that achieved using glass substrates with high-temperature sintering technique (500 °C). Investigating the origin of this difference is a critical step for further improving the performance of plastic dye-sensitized solar cells. In this study, an optimized ternary viscous titania paste without the addition of organic binders enables the fabrication of efficient dye-sensitized solar cells with a low-temperature process. Therefore, the electron-transport behavior of dye-sensitized solar cells can be directly compared with those prepared with the high-temperature sintering technique. In addition to the structural and optical differences, the hot compressed photoanode of dye-sensitized solar cells have an electron diffusion coefficient that is 2 times smaller and a recombination time that is 6 times shorter than those of the high-temperature sintered cells, suggesting inadequate interparticle connections and more recombination events. These results indicate that electron transport and recombination are still the key factors governing the performance of low-temperature fabricated dye-sensitized solar cells. Eventually, the flexible cell with an efficiency of 6.81% has been achieved on flexible indium tin oxide/polyethylene naphthalate substrate. Further improvements in advanced low-temperature processing or novel materials with minimized defect or grain boundaries are required

CoFe₂O₄ Nanoparticles as Oxidase Mimic-Mediated Chemiluminescence of Aqueous Luminol for Sulfite in White Wines

Recently, the intrinsic enzyme-like activity of nanoparticles (NPs) has become a growing area of interest. However, the analytical applications of the NP-based enzyme mimetic are mainly concentrated on their peroxidase-like activity; no attempts have been made to investigate the analytical applications based on the oxidase mimic activities of NPs. For the first time, we report that CoFe₂O₄ NPs were found to possess intrinsic oxidase-like activity and could catalyze luminol oxidation by dissolved oxygen to produce intensified chemiluminescence (CL). The effect of sulfite on CoFe₂O₄ NP oxidase mimic-mediated CL of aqueous luminol was investigated. It is very interesting that when adding sulfite to the luminol–CoFe₂O₄ system, the role of sulfite in the luminol–CoFe₂O₄ NP–sulfite system depends on its concentration. At a relatively low concentration level, sulfite presents an inhibition effect on the luminol–CoFe₂O₄ NP system. However, it does have an enhancement effect at a higher concentration level. Investigations on the effect of the solution pH and luminol and CoFe₂O₄ NP concentrations on the kinetic characteristics of the studied CL system in the presence of trace sulfite suggested that the enhancement and inhibition of the luminol–CoFe₂O₄ NP–sulfite CL system also depended on the solution pH. It seems that the concentrations of luminol and CoFe₂O₄ NPs did not influence the CL pathway. The possible mechanism of the luminol–CoFe₂O₄ NP–sulfite CL system was also discussed. On this basis, a flow injection chemiluminescence method was established for the determination of trace sulfite in this study. Under the optimal conditions, the proposed system could respond down to 2.0 × 10^–8 M sulfite. The method has been applied to the determination of trace sulfite in white wine samples with satisfactory results. The results given by the proposed method are in good agreement with those given by the standard titration method

Optical/Electrical Integrated Design of Core–Shell Aluminum-Based Plasmonic Nanostructures for Record-Breaking Efficiency Enhancements in Photovoltaic Devices

Recently plasmonics has gained tremendous interest in solar cell research because it is capable of improving sunlight-conversion efficiencies. However, plasmonic photovoltaic nanostructures with both excellent optical properties and high electrical conductivities have not been developed, thus limiting the efficiency breakthrough. In this paper, we present an optical/electrical integrated design for plasmonic photovoltaic nanostructures by synthesizing core–shell nanomaterials: aluminum-coated copper nanoparticles. A copper nanocore was synthesized by chemical methods, and then an aluminum nanoshell was physically deposited on the nanocore surface. Strong light-scattering properties have been demonstrated due to the controllable morphology of the nanoparticles and the UV plasmon response of the aluminum nanoshells. Ultrahigh electrical conductivities have been achieved by the pure metallic nanoshells. Once the aluminum-based core–shell particles were integrated into high-efficiency amorphous silicon solar cells, we demonstrated a tremendous efficiency enhancement of 15.4%, which is 51% higher than that from the state-of-the-art plasmonic technique using silver nanostructures

DataSheet5_Mechanism investigation and experiment validation of capsaicin on uterine corpus endometrial carcinoma.ZIP

Background: Using bioinformatics analysis and experimental operations, we intend to analyze the potential mechanism of action of capsaicin target gene GATA1 in the treatment of uterine corpus endometrial carcinoma (UCEC) and develop a prognostic model for the disease to validate this model.Methods: By obtaining capsaicin and UCEC-related DR-DEGs, the prognosis-related gene GATA1 was screened. The survival analysis was conducted via establishing high and low expression groups of GATA1. Whether the GATA1 could be an independent prognostic factor for UCEC, it was also validated. The therapeutic mechanism of capsaicin-related genes in UCEC was further investigated using enrichment analysis and immune methods as well as in combination with single-cell sequencing data. Finally, it was validated by cell experiments.Results: GATA1, a high-risk gene associated with prognosis, was obtained by screening. Kaplan-Meier analysis showed that the survival of the high expression group was lower than that of low expression group. ROC curves showed that the prediction effect of the model was good and stable (1-year area under curve (AUC): 0.601; 2-years AUC: 0.575; 3-years AUC: 0.610). Independent prognosis analysis showed that the GATA1 can serve as an independent prognostic factor for UCEC. Enrichment analysis showed that “neuroactive Ligand - receptor interaction and TYPE I DIABETES MELLITUS” had a significant enrichment effect. Single-cell sequencing showed that the GATA1 was significantly expressed in mast cells. Cell experiments showed that the capsaicin significantly reduced the UCEC cell activity and migration ability, as well as inhibited the expression of GATA1.Conclusion: This study suggests that the capsaicin has potential value and application prospect in the treatment of UCEC. It provides new genetic markers for the prognosis of UCEC patients.</p

DataSheet1_Mechanism investigation and experiment validation of capsaicin on uterine corpus endometrial carcinoma.XLS

Background: Using bioinformatics analysis and experimental operations, we intend to analyze the potential mechanism of action of capsaicin target gene GATA1 in the treatment of uterine corpus endometrial carcinoma (UCEC) and develop a prognostic model for the disease to validate this model.Methods: By obtaining capsaicin and UCEC-related DR-DEGs, the prognosis-related gene GATA1 was screened. The survival analysis was conducted via establishing high and low expression groups of GATA1. Whether the GATA1 could be an independent prognostic factor for UCEC, it was also validated. The therapeutic mechanism of capsaicin-related genes in UCEC was further investigated using enrichment analysis and immune methods as well as in combination with single-cell sequencing data. Finally, it was validated by cell experiments.Results: GATA1, a high-risk gene associated with prognosis, was obtained by screening. Kaplan-Meier analysis showed that the survival of the high expression group was lower than that of low expression group. ROC curves showed that the prediction effect of the model was good and stable (1-year area under curve (AUC): 0.601; 2-years AUC: 0.575; 3-years AUC: 0.610). Independent prognosis analysis showed that the GATA1 can serve as an independent prognostic factor for UCEC. Enrichment analysis showed that “neuroactive Ligand - receptor interaction and TYPE I DIABETES MELLITUS” had a significant enrichment effect. Single-cell sequencing showed that the GATA1 was significantly expressed in mast cells. Cell experiments showed that the capsaicin significantly reduced the UCEC cell activity and migration ability, as well as inhibited the expression of GATA1.Conclusion: This study suggests that the capsaicin has potential value and application prospect in the treatment of UCEC. It provides new genetic markers for the prognosis of UCEC patients.</p

Image2_Mechanism investigation and experiment validation of capsaicin on uterine corpus endometrial carcinoma.PDF

Background: Using bioinformatics analysis and experimental operations, we intend to analyze the potential mechanism of action of capsaicin target gene GATA1 in the treatment of uterine corpus endometrial carcinoma (UCEC) and develop a prognostic model for the disease to validate this model.Methods: By obtaining capsaicin and UCEC-related DR-DEGs, the prognosis-related gene GATA1 was screened. The survival analysis was conducted via establishing high and low expression groups of GATA1. Whether the GATA1 could be an independent prognostic factor for UCEC, it was also validated. The therapeutic mechanism of capsaicin-related genes in UCEC was further investigated using enrichment analysis and immune methods as well as in combination with single-cell sequencing data. Finally, it was validated by cell experiments.Results: GATA1, a high-risk gene associated with prognosis, was obtained by screening. Kaplan-Meier analysis showed that the survival of the high expression group was lower than that of low expression group. ROC curves showed that the prediction effect of the model was good and stable (1-year area under curve (AUC): 0.601; 2-years AUC: 0.575; 3-years AUC: 0.610). Independent prognosis analysis showed that the GATA1 can serve as an independent prognostic factor for UCEC. Enrichment analysis showed that “neuroactive Ligand - receptor interaction and TYPE I DIABETES MELLITUS” had a significant enrichment effect. Single-cell sequencing showed that the GATA1 was significantly expressed in mast cells. Cell experiments showed that the capsaicin significantly reduced the UCEC cell activity and migration ability, as well as inhibited the expression of GATA1.Conclusion: This study suggests that the capsaicin has potential value and application prospect in the treatment of UCEC. It provides new genetic markers for the prognosis of UCEC patients.</p

DataSheet4_Mechanism investigation and experiment validation of capsaicin on uterine corpus endometrial carcinoma.ZIP

Background: Using bioinformatics analysis and experimental operations, we intend to analyze the potential mechanism of action of capsaicin target gene GATA1 in the treatment of uterine corpus endometrial carcinoma (UCEC) and develop a prognostic model for the disease to validate this model.Methods: By obtaining capsaicin and UCEC-related DR-DEGs, the prognosis-related gene GATA1 was screened. The survival analysis was conducted via establishing high and low expression groups of GATA1. Whether the GATA1 could be an independent prognostic factor for UCEC, it was also validated. The therapeutic mechanism of capsaicin-related genes in UCEC was further investigated using enrichment analysis and immune methods as well as in combination with single-cell sequencing data. Finally, it was validated by cell experiments.Results: GATA1, a high-risk gene associated with prognosis, was obtained by screening. Kaplan-Meier analysis showed that the survival of the high expression group was lower than that of low expression group. ROC curves showed that the prediction effect of the model was good and stable (1-year area under curve (AUC): 0.601; 2-years AUC: 0.575; 3-years AUC: 0.610). Independent prognosis analysis showed that the GATA1 can serve as an independent prognostic factor for UCEC. Enrichment analysis showed that “neuroactive Ligand - receptor interaction and TYPE I DIABETES MELLITUS” had a significant enrichment effect. Single-cell sequencing showed that the GATA1 was significantly expressed in mast cells. Cell experiments showed that the capsaicin significantly reduced the UCEC cell activity and migration ability, as well as inhibited the expression of GATA1.Conclusion: This study suggests that the capsaicin has potential value and application prospect in the treatment of UCEC. It provides new genetic markers for the prognosis of UCEC patients.</p

DataSheet3_Mechanism investigation and experiment validation of capsaicin on uterine corpus endometrial carcinoma.ZIP

Background: Using bioinformatics analysis and experimental operations, we intend to analyze the potential mechanism of action of capsaicin target gene GATA1 in the treatment of uterine corpus endometrial carcinoma (UCEC) and develop a prognostic model for the disease to validate this model.Methods: By obtaining capsaicin and UCEC-related DR-DEGs, the prognosis-related gene GATA1 was screened. The survival analysis was conducted via establishing high and low expression groups of GATA1. Whether the GATA1 could be an independent prognostic factor for UCEC, it was also validated. The therapeutic mechanism of capsaicin-related genes in UCEC was further investigated using enrichment analysis and immune methods as well as in combination with single-cell sequencing data. Finally, it was validated by cell experiments.Results: GATA1, a high-risk gene associated with prognosis, was obtained by screening. Kaplan-Meier analysis showed that the survival of the high expression group was lower than that of low expression group. ROC curves showed that the prediction effect of the model was good and stable (1-year area under curve (AUC): 0.601; 2-years AUC: 0.575; 3-years AUC: 0.610). Independent prognosis analysis showed that the GATA1 can serve as an independent prognostic factor for UCEC. Enrichment analysis showed that “neuroactive Ligand - receptor interaction and TYPE I DIABETES MELLITUS” had a significant enrichment effect. Single-cell sequencing showed that the GATA1 was significantly expressed in mast cells. Cell experiments showed that the capsaicin significantly reduced the UCEC cell activity and migration ability, as well as inhibited the expression of GATA1.Conclusion: This study suggests that the capsaicin has potential value and application prospect in the treatment of UCEC. It provides new genetic markers for the prognosis of UCEC patients.</p

Image7_Mechanism investigation and experiment validation of capsaicin on uterine corpus endometrial carcinoma.PDF

Background: Using bioinformatics analysis and experimental operations, we intend to analyze the potential mechanism of action of capsaicin target gene GATA1 in the treatment of uterine corpus endometrial carcinoma (UCEC) and develop a prognostic model for the disease to validate this model.Methods: By obtaining capsaicin and UCEC-related DR-DEGs, the prognosis-related gene GATA1 was screened. The survival analysis was conducted via establishing high and low expression groups of GATA1. Whether the GATA1 could be an independent prognostic factor for UCEC, it was also validated. The therapeutic mechanism of capsaicin-related genes in UCEC was further investigated using enrichment analysis and immune methods as well as in combination with single-cell sequencing data. Finally, it was validated by cell experiments.Results: GATA1, a high-risk gene associated with prognosis, was obtained by screening. Kaplan-Meier analysis showed that the survival of the high expression group was lower than that of low expression group. ROC curves showed that the prediction effect of the model was good and stable (1-year area under curve (AUC): 0.601; 2-years AUC: 0.575; 3-years AUC: 0.610). Independent prognosis analysis showed that the GATA1 can serve as an independent prognostic factor for UCEC. Enrichment analysis showed that “neuroactive Ligand - receptor interaction and TYPE I DIABETES MELLITUS” had a significant enrichment effect. Single-cell sequencing showed that the GATA1 was significantly expressed in mast cells. Cell experiments showed that the capsaicin significantly reduced the UCEC cell activity and migration ability, as well as inhibited the expression of GATA1.Conclusion: This study suggests that the capsaicin has potential value and application prospect in the treatment of UCEC. It provides new genetic markers for the prognosis of UCEC patients.</p