Anthracene-Fused BODIPYs as Near-Infrared Dyes with High Photostability

An anthracene unit was successfully fused to the zigzag edge of a boron dipyrromethene (BODIPY) core by an FeCl₃-mediated oxidative cyclodehydrogenation reaction. Meanwhile, a dimer was also formed by both intramolecular cyclization and intermolecular coupling. The anthracene-fused BODIPY monomer <b>7a</b> and dimer <b>7b</b> showed small energy gaps (∼1.4 eV) and near-infrared absorption/emission. Moreover, they exhibited high photostability

Pd-Catalyzed Intramolecular Aerobic Oxidative C–H Amination of 2‑Aryl-3-(arylamino)­quinazolinones: Synthesis of Fluorescent Indazolo­[3,2‑<i>b</i>]­quinazolinones

A palladium-catalyzed intramolecular aerobic oxidative C–H amination of 2-aryl-3-(arylamino)­quinazolinones has been developed, providing a variety of substituted indazolo­[3,2-<i>b</i>]­quinazolinone derivatives in moderate to excellent yields. Preliminary mechanistic studies suggested that a palladacycle dimer could be the key intermediate, which underwent a cascade “rollover” cyclometalation and C–H amination sequence. Furthermore, the potential utility of these products has been demonstrated as a new class of blue fluorophores for fluorescent materials

Data_Sheet_1_Functional traits and phylogeny jointly regulate the effects of environmental filtering and dispersal limitation on species spatial distribution.ZIP

IntroductionRevealing the spatial distribution pattern and formation mechanism of species in a community can provide important clues for community renewal, succession, and diversity maintenance mechanisms.MethodsIn this study, we employed spatial point process modeling to identify and quantify the processes contributing to the spatial distribution of species. Simultaneously, we explored the relationship between functional traits and species spatial distribution characteristics in conjunction with phylogenetic studies.ResultsThe results revealed that the LGCP model effectively described all species, indicating that the spatial pattern of species may be influenced by a combination of environmental filtering and dispersal limitation. Disparities in species spatial distribution were elucidated by characterizing functional traits, such as body size and resource conservation. Incorporating phylogenetic information enhanced the predictive capacity of functional traits in explaining species spatial distribution.DiscussionThis study underscores the significance of the joint effects of environmental filtering and dispersal limitation in generating species spatial distribution patterns. Integrating spatial point process models with considerations of functional traits and phylogeny proves to be an effective approach for comprehending the mechanisms governing species combinations.</p

Data_Sheet_2_Functional traits and phylogeny jointly regulate the effects of environmental filtering and dispersal limitation on species spatial distribution.csv

IntroductionRevealing the spatial distribution pattern and formation mechanism of species in a community can provide important clues for community renewal, succession, and diversity maintenance mechanisms.MethodsIn this study, we employed spatial point process modeling to identify and quantify the processes contributing to the spatial distribution of species. Simultaneously, we explored the relationship between functional traits and species spatial distribution characteristics in conjunction with phylogenetic studies.ResultsThe results revealed that the LGCP model effectively described all species, indicating that the spatial pattern of species may be influenced by a combination of environmental filtering and dispersal limitation. Disparities in species spatial distribution were elucidated by characterizing functional traits, such as body size and resource conservation. Incorporating phylogenetic information enhanced the predictive capacity of functional traits in explaining species spatial distribution.DiscussionThis study underscores the significance of the joint effects of environmental filtering and dispersal limitation in generating species spatial distribution patterns. Integrating spatial point process models with considerations of functional traits and phylogeny proves to be an effective approach for comprehending the mechanisms governing species combinations.</p

Semisynthesis of Esters of Fraxinellone C4/10-Oxime and Their Pesticidal Activities

A total of 20 esters of fraxinellone C4/10-oxime were synthesized and determined by melting points, optical rotation, infrared spectra, proton nuclear magnetic resonance spectra, and high-resolution mass spectrometry spectra. Two steric configurations of compounds <b>7i</b> and <b>8i</b> were unambiguously confirmed by X-ray crystallography. Additionally, their pesticidal activities were assessed on two typical lepidopteran pests, Mythimna separata Walker and Plutella xylostella Linnaeus. Generally, all compounds exhibited less potent oral toxicity than toosendanin against third-instar larvae of P. xylostella. However, all compounds showed the growth inhibitory property against early third-instar larvae of M. separata. Notably, compounds <b>7m</b>, <b>8b</b>, <b>8k</b>, <b>9</b>, and <b>11</b> displayed more potent pesticidal activity than toosendanin. This demonstrated that introducing the C-4 carbonyl or oxime group on fraxinellone resulted in more promising derivatives than those bearing a C-10 carbonyl or oxime substituent

Pd-Catalyzed Intramolecular Aerobic Oxidative C–H Amination of 2‑Aryl-3-(arylamino)­quinazolinones: Synthesis of Fluorescent Indazolo­[3,2‑<i>b</i>]­quinazolinones

A palladium-catalyzed intramolecular aerobic oxidative C–H amination of 2-aryl-3-(arylamino)­quinazolinones has been developed, providing a variety of substituted indazolo­[3,2-<i>b</i>]­quinazolinone derivatives in moderate to excellent yields. Preliminary mechanistic studies suggested that a palladacycle dimer could be the key intermediate, which underwent a cascade “rollover” cyclometalation and C–H amination sequence. Furthermore, the potential utility of these products has been demonstrated as a new class of blue fluorophores for fluorescent materials

Elderly-Onset Paroxysmal Kinesigenic Dyskinesia: A Case Report

Article full text The article associated with this page has been accepted for online publication and is in the final stages of production. The link to the full text will be made available on this page in the next few days. The above patient video represents the opinions of the authors. For a full list of declarations, including funding and author disclosure statements, please see the full text online (see “read the peer-reviewed publication” opposite).  © The authors, CC-BY-NC 2022.  </p

Synergistic Photo-Copper-Catalyzed Hydroxylation of (Hetero)aryl Halides with Molecular Oxygen

Photoredox-mediated copper-catalyzed hydroxylation of (hetero)­aryl halides (including chlorides, bromides, and iodides) with O₂ at room temperature has been developed. Preliminary mechanistic studies indicate no arylcopper intermediate and that aryl radicals are involved in this procedure. ¹⁸O-labeling experiments confirm the hydroxyl oxygen atom originated from molecular oxygen

9‑Ethynylfluoroenyl Radicals: Regioselective Dimerization and Post Ring-Cyclization Reactions

9-Ethynylfluorenyl radical derivatives were readily prepared in situ and underwent simultaneous intermolecular coupling reactions. Interestingly, the dimerization process took place in either a head-to-tail or a head-to-head mode between the acetylenic or the allenic resonance forms dependent on the terminal substituents, which could be well explained by their different spin distribution and steric hindrance effects. The structures of the products were confirmed by X-ray crystallographic and other spectroscopic analyses. It was also found that the newly generated dipropinyl dimers underwent a rearrangement and ring-cyclization reaction at room temperature, eventually giving unique difluorenylidene cyclobutene derivatives