5 research outputs found

    Effect of adiponectin overexpression on collagen production.

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    <p>Content of (A) procollagen I, (B) procollagen III, (C) collagen I, (D) collagen III. Data are representative of 3 independent experiments (means±SD). *, <i>p</i><0.05 vs. con; #, <i>p</i><0.05 vs. IL-6.</p

    Effect of dose and time of adiponectin treatment on to P4Hα1 expression.

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    <p>(A and C) mRNA expression of P4Hα1. (B and D) Protein expression of P4Hα1. Data are representative of 3 independent experiments (means±SD). *, <i>p</i><0.05 vs. con; #, <i>p</i><0.05 vs. IL-6.</p

    Sp1 regulates the effect of adiponectin upregulating P4Hα1 expression in IL-6-mediated HASMCs.

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    <p>(A) Sp1 DNA binding activity. (B) Subcellular localization of Sp1. (C) mRNA expression of P4Hα1. (D) Protein expression of P4Hα1. *, <i>p</i><0.05 vs. con; #, <i>p</i><0.05 vs. IL-6.</p

    ERK1/2 leads to adiponectin upregulating P4Hα1 expression in IL-6-stimulated HASMCs.

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    <p>(A) p-ERK level. (B) Sp1 DNA-binding activity. (C) Subcellular localization of Sp1. (D) mRNA expression of P4Hα1. (E) Protein expression of P4Hα1. *, <i>p</i><0.05 vs. con; #, <i>p</i><0.05 vs. IL-6.</p

    Effect of dose and time of IL-6 treatment on P4Hα1 expression.

    No full text
    <p>(A and C) mRNA expression of P4Hα1. (B and D) Protein expression of P4Hα1. Data are representative of 3 independent experiments (means±SD). *, <i>p</i><0.05 vs. con.</p
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