51 research outputs found

    Communicating an arts foundation’s values: sights, sounds and social media

    Get PDF
    Purpose This paper tests and refines the long-established signal transmission model of the communication process by examining the ways in which a newly-formed nonprofit arts foundation communicated its professed values to its stakeholders. Methodological approach The study uses a mixed method case study approach. Interviews with key informants and observations of the foundation’s webpages enabled the identification of the professed values of the arts foundation. Next, a questionnaire survey established whether these values had been successfully decoded by stakeholders and identified the channels via which the values-related signals had been received. Findings The transmission model was found to be relevant as a model. However, to improve its fit within a nonprofit arts context, a modification to the model is suggested which highlights the importance of multi-sensory channels, the importance of context, and the increasingly important role of the stakeholder. Research limitations This study is a small-scale case study, although its mixed methods help to ensure validity. Practical implications The findings will help nonprofit arts organisations to decide on how to best communicate their values to their stakeholders. Social implications A determination by an organisation to uphold an uplifting range of values, such as those which were found to be transmitted by Folkstock, impacts upon society by the potential contribution to a better quality of life. Originality /value Literature which provides in-depth examination of the communication of values within a nonprofit arts context via a range of channels, including traditional, online and multi-sensory, is sparse. The opportunity to study a newly-formed nonprofit arts organisation is also rare. The results of this study provide valuable evidence that even in today’s social media-rich world, people, sounds, sights and material objects in physical space still have a vital role to play in the communication of values

    A randomized, open-label, multicentre, phase 2/3 study to evaluate the safety and efficacy of lumiliximab in combination with fludarabine, cyclophosphamide and rituximab versus fludarabine, cyclophosphamide and rituximab alone in subjects with relapsed chronic lymphocytic leukaemia

    Get PDF

    The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Get PDF
    To dissect the genetic architecture of blood pressure and assess effects on target-organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry and genotypes from an additional 140,886 individuals were used for validation. We identified 66 blood pressure loci, of which 17 were novel and 15 harbored multiple distinct association signals. The 66 index SNPs were enriched for cis-regulatory elements, particularly in vascular endothelial cells, consistent with a primary role in blood pressure control through modulation of vascular tone across multiple tissues. The 66 index SNPs combined in a risk score showed comparable effects in 64,421 individuals of non-European descent. The 66-SNP blood pressure risk score was significantly associated with target-organ damage in multiple tissues, with minor effects in the kidney. Our findings expand current knowledge of blood pressure pathways and highlight tissues beyond the classic renal system in blood pressure regulation

    Sterile Debates and Dubious Generalisations: An Empirical Critique of European Integration Theory Based on the Integration Processes in Telecommunications and Electricity

    Full text link
    • 

    corecore