Detection of Helicobacter Pylori CagA Gene and Its Association with Endoscopic Appearance in Balinese Dyspepsia Patients

Background: Helicobacter pylori (H. pylori) infection causes various abnormalities in the stomach. Only particular strain can cause severe problems in the stomach. CagA is a microbial virulent factor which is associated with more severe stomach problems, such as: peptic ulcer and stomach cancer. We would like to know the prevalence of CagA in Balinese population, and the association of H. Pylori CagA status with the severity of endoscopic appearance in dyspepsia patients.Method: Study design being used was analytic cross sectional study, involving 71 dyspepsia patients who underwent upper gastrointestinal endoscopic examination in Surya Husada Hospital and Balimed Hospital in June-December 2013. Sample was chosen in consecutive manner. Later, polymerase chain reaction (PCR) examinations of the stomach mucous biopsy tissue to determine H. pylori infection status and CagA status were performed. Further, Chi square test was used to identify the difference in proportion of H. pylori and CagA between mild and severe endoscopic appearance.Results: In this study, we found that the prevalence of H. pylori infection was 22.5% using PCR examination. Prevalence of CagA positive in H. pylori positive was 62.5%. There was significant association between status of H. Pylori infection and severity of endoscopic appearance (p = 0.038; OR= 2.67; 95% CI = 1.18-6.05). Status of CagA in H. pylori infected patients was not associated with the severity of endoscopic appearance. Additionally, there was significant association between patients' age and severity of endoscopic appearance.Conclusion: The prevalence of CagA in H. pylori positive was 62.5%. H. pylori infection was associated with severity of endoscopic appearance and CagA status in H. pylori infected patients was not associated with severity of endoscopic appearance

Efektivitas dan Dampak Program SIMANTRI terhadap Pendapatan dan Kesempatan Kerja Rumah Tangga Petani di Desa Kelating Kecamatan Kerambitan Kabupaten Tabanan

To accelerate the growth and development of agriculture in the rural area and at the same time reducing the poverty and unemployment in the rural area, the government launched the Integrated Agricultural System Program (SIMANTRI), where the SIMANTRI program is an breakthrough effort in accelerating agricultural technology adoption which is the improvement of pilot project in accelerating technology transfer to the rural community for the purpose to improve the income and work opportunity of farmer's household. The research entitled “The Effectiveness and the Impact of SIMANTRI Program to the Income and Work Opportunity of Farmer's Household at Kelating Village Sub-district of Kerambitan Regency of Tabanan” aims to measure the level of effectiveness and impact of SIMANTRI program to the income and work opportunity of farmer's household at Kelating Village Sub-district of Kerambitan Regency of Tabanan. Analysis tool used in this research is descriptive statistical to find out the program effectiveness and non-parametric differential test statistical analysis to find out SIMANTRI program impact to the income and work opportunity of farmer's household at Kelating Village Sub-district of Kerambitan Regency of Tabanan. Analysis result shows that SIMANTRI program effectiveness at 98.94% means effectiveness level of the Integrated Agricultural System Program (SIMANTRI) is very effective. Analysis result also shows that SIMANTRI program has positive and significant impact to the income and work opportunity of farmer's household at Kelating Village Sub-district of Kerambitan Regency of Tabanan

Pelatihan Meniti Papan Jarak 4 Meter 5 Repetisi 2 Set dan 2 Repetisi 5 Set terhadap Peningkatan Keseimbangan Siswa Kelas VIII SMP Negeri 3 Mengwi Tahun Pelajaran 2015/2016

Berdasarkan hasil pengamatan awal, SMP Negeri 3 Mengwi sudah sering mengikuti kejuaraan di bidang olahraga, baik ditingkat kabupaten maupun provinsi, akan tetapi para pemain SMP Negeri 3 Mengwi belum dapat menunjukkan hasil yang maksimal dalam meraih prestasi, untuk lebih meningkatkan prestasi yang dimiliki, maka penulis mencoba melaksanakan penelitian yang berjudul Pelatihan Meniti Papan Berjarak 4 Meter 5 Repetisi 2 Set dan 2 Repetisi 5 Set Terhadap Peningkatan Keseimbangan Siswa Kelas VIII SMP N 3 Mengwi Tahun Pelajaran 2015-2016. Berdasarkan latar belakang masalah di atas, maka masalah-masalah dalam penelitian ini adalah apakah ada pengaruh dan perbedaan pengaruh Pelatihan Meniti Papan Berjarak 4 Meter 5 Repetisi 2 Set dan 2 Repetisi 5 Set Terhadap Peningkatan Keseimbangan Siswa Kelas VIII SMPN 3 Mengwi Tahun Pelajaran 2015-2016? Adapun tujuan dari penelitian ini adalah untuk mengetahui adanya pengaruh dan perbedaan pengaruh Pelatihan Meniti Papan Berjarak 4 Meter 5 Repetisi 2 Set dan 2 Repetisi 5 Set Terhadap Peningkatan Keseimbangan Siswa Kelas VIII SMPN 3 Mengwi Tahun Pelajaran 2015-2016. Populasi dalam penelitian ini adalah siswa putra kelas VIII SMP Negeri 3 Mengwi Tahun Pelajaran 2015/2016 yang berjumlah 60 orang, dalam penelitian ini jumlah populasi di gunakan sebagai sampel sebanyak 60 orang sampel. Analisis data mempergunakan metode analisis statistik dengan rumus t-tes. Dari hasil analisis data didapatkan perbedaan kelompok experimen pertama dan kedua didapatkan t-hitung sebesar 0,540 sedangkan t-tabel didapat sebesar 2,000 dengan taraf signifikan 5% dan db=58. Berdasarkan hasil analisis data diatas dapat disimpulkan bahwa ada Perbedaan pengaruh yang tidak signifikan Pelatihan Meniti Papan Berjarak 4 Meter 5 Repetisi 2 Set dan 2 Repetisi 5 Set Terhadap Peningkatan Keseimbangan Siswa Kelas VIII SMPN 3 Mengwi Tahun Pelajaran 2015-2016

Association Between Red Cell Distribution Width (RDW)/Platelet Ratio and Degree of Fibrosis in Patient with Chronic Hepatitis B

Background : Histological examination of the liver remains the gold standard of assessing liver cirrhosis. However, this examination is an invasive method with many complications.Objectives : This study aims to determine the relationship between degree of liver fibrosis with RDW (Red cell Distribution Width) / platelet ratio which can then be used as non invasive diagnostic method of liver fibrosis. Methods : This was a retrospective study, the data of hematological profiles including hemoglobin, RDW, and platelet was taken from medical records of all chronic hepatitis B patients undergoing Fibroscan at Sanglah Hospital in January 2016 to February 2017. Results : Of 58 patients, 9 patients was excluded due to chronic kidney disease, Malignancy and coincide with hepatitis C and HIV. The analysis using Kruskal-Wallis test, found a significant relationship between RDW / platelet ratio with degree of fibrosis in chronic hepatitis B (p<0.05). Of the 49 patients, 23 patients with mild-moderate fibrosis (metavir F0-2) and 26 patients with severe fibrosis (metavir F3-4) were found. In ROC analysis, the AUC was 0.701, using cut off 0,065 RDW/platelet ratio predict severe fibrosis about 73.1% sensitivity, spesificity 73.9%, positive prediction value 73.1%, and negative prediction value 70.8%. Conclusion : the RDW / platelet ratio can be used as a noninvasive diagnostic test of liver fibrosis in chronic hepatitis B patients

Positive Correlation Between Degree of Liver Cirrhosis and N Terminal–Pro Brain Natriuretic Peptide (NT-pro-BNP)

Background: Liver cirrhosis (LC) is a chronic disease characterized by damage of liver parenchyme with wide fibrosis and nodules formation. One of LC complications is cirrhotic cardiomyopathy (CC). CC is diagnosed when there are more than one of the following signs: diastolic dysfunction (DD), systolic dysfunction (SD), enlargement of the cardiac chamber, electrophysiology dysfunction, and increasing of natriuretic peptide such as N Terminal–Pro Brain Natriuretic Peptide (NT-proBNP). The aim of this study was to determine the correlation between degree of liver cirrhosis and increasing of the NT-proBNP.Method: Cross-sectional analytic study was performed with 72 LC patients from May 2014 to May 2015 in Sanglah General Hospital, Denpasar. Degree of liver cirrhosis was determined by child turcotte pugh (CTP) criteria and NT-proBNP was examined by electro chemiluminescence immunoassay (ECLIA) method. LC patients with other disorders which can cause the increase of NT-proBNP were excluded. Statistical analysis used was Spearman's correlation test. Results: Of 72 LC patients, 79.2% were male. Patients with CTP A were 9 (12,5%), CTP B 19 (26,4%) and CTP C 44 (61,19%). Median of NT-proBNP in CTP A was 112 pg/mL, CTP B 130 pg/mL, and CTP C 315 pg/ml. There was a strong possitive correlation between degree of liver cirrhosis and NT-proBNP (r = 0.686; p = 0.000). In this study, there was also significant comparison between NT-proBNP and CTP A,B, and C (p = 0,000) and there was no significant relation between NT-proBNP and those cofounding variables (p > 0.05).Conclusion: there was a strong possitive correlation between degree of LC and NT-proBNP

High Incidence of Hepatitis B Virus Infection in Hemodialysis Patients at Sanglah General Hospital and IT\u27s Risk Factors

Background: Patients receiving maintenance hemodialysis (HD) are at higher risk for Hepatitis B Virus (HBV) infections than in general population. Strict infection control is essential to prevent nosocomial transmission. We aimed to investigate the incidence of HBV infection in the HD population in Sanglah General Hospital as well as risk factors acquired HBV infection.Method: All adult patients receiving maintenance HD (n=267) in 3 dialysis units at Sanglah Hospital were studied between March to June 2016. In this study, medical record of patients on maintenance hemodialysis were reviewed and the patients were interviewed by the researchers to collect data regarding the serology status of these patients before and during HD, and potential risk factors which could be associated with HBV acquisition.Results: Participant mean age was 54.07 ± 0.80 years and 154 (57.7%) were male.We found 21 patients (7.8%) were sero-positive for HBV (HBsAg positive) with mean titer was 9.26±1.85. Of the sero-positive patients,1 patient (4.8%) were known to be infected before the initiation of HD and 20 patients (95.2%) were infected during HD. Incidence of HBV infection during HD was 7.5% (20/266). Sero-positive patients were younger with mean age was 51.81±2.76 years, had longer time on dialysis and had previous blood transfusions. Risk factors, which significant associated with hepatitis B infection were history of transfusion (p<0.01; OR: 2.49; 95%CI: 1.29-8.18) and duration of hemodialysis (p < 0.01; OR: 1.07; 95% CI: 1.03-3.74).Conclusion: Patients on maintenance HD in Sanglah General Hospital have a high incidence of HBV infection. The factors associated with HBV infection are highly suggestive of nosocomial transmission within HD units. History of transfusion and duration of hemodialysis were significant risk factors for HBV infection in patients receiving maintenance HD

Pengaruh Keterlibatan Kerja terhadap Kinerja dengan Pemediasi Komitmen Organisasional

This study examined the effect of job involvement on job performance and organizational commitment as mediation. This study involved 135 respondents and using saturated sample which take all employee become a respondents. Likert Scale is used as a balanced assessment questionnaires and using validity and reliability for testing questionaires. The analysis tool in the research is Structural Equation Model (SEM) which using a variance-based approach with Partial Least Square (PLS) as well as to test the mediating variable VAF to testing. Result of study found that job involvement has a positive effect on organizational commitment and job performance at Defense of Ministry. Organizational commitment has positive influence on job performance at Pusat Keuangan and organizational commitment as Partial mediation proved directly affect the relationship between job involvement and job performance. can be given to the Defense of Ministry is increasing attention to the dimensions of salary, normative commitment, and discipline work as dimensions that have bad perceptio

Diseminasi Teknologi Bali-bio Serta Pemanfaatannya Dalam Pengembangan Peternakan Sapi Bali Di Desa Abiantuwung

Ipteks bagi Masyarakat/IbM telah dilaksanakan di Kelompok Ternak Sapi Bali Bina Satwa I (mitra I) dan Bina satwa III (mitra II) Desa Abiantuwung, Kediri Tabanan dalam optimalisasi pemanfaatan limbah pada pengembangan peternakan sapi Bali. Teknologi produksi bioinokulan berbasis limbah cairan rumen sapi Bali Bali-bio dan pemanfaatan dalam produksi silase pakan berbasis limbah dan pupuk organik didesiminasikan kepada kedua mitra melalui kegiatan penyuluhan, pelatihan singkat, dan pembentukan demoplot. Hasil kegiatan menunjukkan partisifasi mitra dalam seluruh kegiatan sangat tinggi, kegiatan penyuluhan dan pelatihan singkat diikuti 100% anggota kedua mitra serta 53,3% mitra I dan 60% mitra II mengajukan permasalahan produksi ternak sapi Bali dan tata cara pemanfaatan limbah. Pada pelaksanaan kegiatan demoplot diketahui transfer teknologi produksi bioinokulan Bali-bio, silase pakan berbasis limbah dan pupuk organik dapat terlaksana dengan baik, 73,3% mitra I dan 80% mitra II dapat memproduksi produk secara mandiri dengan kualitas baik. Berdasarkan hasil evaluasi kegiatan dapat disimpulkan desiminasi teknologi di kedua mitra telah terlaksana dengan baik dengan tingkat partisipasi mitra dan daya adopsi ipteks yang cukup tinggi

Age and Alarm Symptoms Predict Upper Gastrointestinal Malignancy Among Patients with Dyspepsia

Background: Upper gastrointestinal (UGI) Malignancy is one of the major causes of cancer related death. Endoscopy in dyspeptic patients above 45 years, or those with alarm symptoms may detect this condition. There were only limited data in Indonesia about age and alarm symptoms to predict UGI Malignancy. This study was aimed to determine the prevalence of UGI Malignancy among dyspepsia patients and to develop a simple clinical prediction model.Method: A cross-sectional study to 390 patients with dyspepsia underwent endoscopy in Endoscopy Unit of Sanglah Hospital Denpasar between July 2012 and June 2013 was conducted. Demography and alarm symptoms were documented. Chi-square and logistic regression test analysis were conducted to analyze variables associated with UGI Malignancy.Results: Twenty (5.13%) of 390 patients with dyspepsia had UGI Malignancy. Of the 20 patients, 65% were gastric cancer and 30% were esophageal cancer. The mean age was 59 ± 12 years. Variables associated with UGI Malignancy were weight loss (OR = 8.2), dysphagia (OR = 6.2), age &gt; 45 years old (OR = 5.6), gastrointestinal bleeding (OR = 5.5), persistent vomiting (OR = 5.4), and anemia (OR = 4.9). Using a simplified rule of age &gt;45 years and the presence of any alarm symptom, sensitivity was 85% and specificity was 67.57%.Conclusions: UGI Malignancy was found in 5.13% of patients with dyspepsia who underwent endoscopy. Simple clinical prediction model states that age above 45 years and alarm symptoms may be used as a screening tool to predict UGI Malignancy