37 research outputs found

    Climate Smart Farming for Women in East Africa

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    According to the United Nations Food and Agriculture Organization, 60% of East Africans live as subsistence farmers. This population is particularly vulnerable to the effects of climate change which has increased the duration and intensity of droughts and floods. Droughts and floods can destroy an entire season’s harvest, causing sustenance farmers and their families to struggle for food until the next season. In an attempt to mitigate the severe effects of climate change on these farmers and reduce food insecurity in East Africa, the team has designed a small-scale aquaponic farming system that simultaneously grows fish and vegetables. This system is founded on sustainability, as aquaponics uses significantly less water to grow crops than traditional farming, making it more resilient to both severe droughts and floods, the system also does not rely on external fertilizers, and it uses recycled materials as often as possible. This aquaponic system was designed for women’s collectives in East Africa who requested help in building a portfolio of projects that they can teach to women in rural East Africa. These women’s organizations work in rural villages throughout Uganda and Kenya to help local women and their families adapt to the changing climate. Currently, their efforts have been focused on improving the quality and supply of water in the villages by constructing latrines, water filters, and rainwater catchment systems. During the 2017-2018 academic year, team members designed and built the aquaponic system in Santa Clara, California, then deployed the first prototype in Kampala, Uganda, and trained several of the collective’s leaders how to build and operate the system

    Automated acoustic detection of Geoffroy's spider monkey highlights tipping points of human disturbance

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    As more land is altered by human activity and more species become at risk of extinction, it is essential that we understand the requirements for conserving threatened species across human-modified landscapes. Owing to their rarity and often sparse distributions, threatened species can be difficult to study and efficient methods to sample them across wide temporal and spatial scales have been lacking. Passive acoustic monitoring (PAM) is increasingly recognized as an efficient method for collecting data on vocal species; however, the development of automated species detectors required to analyse large amounts of acoustic data is not keeping pace. Here, we collected 35 805 h of acoustic data across 341 sites in a region over 1000 km2 to show that PAM, together with a newly developed automated detector, is able to successfully detect the endangered Geoffroy's spider monkey (Ateles geoffroyi), allowing us to show that Geoffroy's spider monkey was absent below a threshold of 80% forest cover and within 1 km of primary paved roads and occurred equally in old growth and secondary forests. We discuss how this methodology circumvents many of the existing issues in traditional sampling methods and can be highly successful in the study of vocally rare or threatened species. Our results provide tools and knowledge for setting targets and developing conservation strategies for the protection of Geoffroy's spider monkey

    The general population cohort in rural south-western Uganda: a platform for communicable and non-communicable disease studies.

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    The General Population Cohort (GPC) was set up in 1989 to examine trends in HIV prevalence and incidence, and their determinants in rural south-western Uganda. Recently, the research questions have included the epidemiology and genetics of communicable and non-communicable diseases (NCDs) to address the limited data on the burden and risk factors for NCDs in sub-Saharan Africa. The cohort comprises all residents (52% aged ≥13years, men and women in equal proportions) within one-half of a rural sub-county, residing in scattered houses, and largely farmers of three major ethnic groups. Data collected through annual surveys include; mapping for spatial analysis and participant location; census for individual socio-demographic and household socioeconomic status assessment; and a medical survey for health, lifestyle and biophysical and blood measurements to ascertain disease outcomes and risk factors for selected participants. This cohort offers a rich platform to investigate the interplay between communicable diseases and NCDs. There is robust infrastructure for data management, sample processing and storage, and diverse expertise in epidemiology, social and basic sciences. For any data access enquiries you may contact the director, MRC/UVRI, Uganda Research Unit on AIDS by email to [email protected] or the corresponding author

    Liberal warriors and the violent colonial logics of “partnering and advising"

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    Building on the feminist literature that traces the (re)production of militarized masculinities in and through military interventions, this article details some of the ways British soldiering subjects are being shaped in today's counterinsurgency context. Required now to be both nation builders and war fighters, contemporary soldiers are a “softer,” less masculinized subjectivity, and what Alison Howell has termed “liberal warriors.” British troops with their long history of colonialism and frequent overseas military campaigns are understood to be particularly suited to this role. Taking the British military's involvement in the “partnering and advising” of the Afghan National Army (ANA), this article pays attention to the interlocking gendered, raced, and sexualized discourses through which the British/Afghan encounter is experienced. Exploring first British troops' preoccupation with the perceived femininity and homosexuality of their Afghan counterparts, and second, Afghan hypermasculinity as demonstrated by the characterizations of their violent and chaotic fighting tactics, colonial logics are revealed. While British liberal warriors come to know “who they are” through these logics, (mis)represented Afghan soldiers are rendered increasingly vulnerable to the very “real,” very material violences of war

    Incidence of SARS-CoV-2 over four epidemic waves in a low-resource community in Rio de Janeiro, Brazil: A prospective cohort study.

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    BACKGROUND: Incidence rates of SARS-CoV-2 infections in low-resource communities can inform vaccination strategies and non-pharmaceutical interventions (NPIs). Our objective was to estimate incidence over four epidemic waves in a slum in Rio de Janeiro, a proxy for economically deprived areas in the Global South. METHODS: Prospective cohort of children and household contacts screened for SARS-CoV-2 by PCR and serology (IgG). The incidence density of PCR positive infections estimated for each wave - the first wave, Zeta, Gamma and Delta - was compared to an index combining NPIs and vaccination coverage. FINDINGS: 718 families and 2501 individuals were enrolled, from May 2020 to November 2021. The incidence density of SARS-CoV-2 infection due to the first wave was 2, 3 times that of the other waves. The incidence among children was lower than that of older participants, except in later waves, when vaccination of the elderly reached 90%. Household agglomeration was significantly associated with incidence only during the first wave. INTERPRETATION: The incidence of infection greatly exceeded rates reported in similar cohorts. The observed reduction in incidence in the elderly during the Delta variant wave, in spite of the rollback of NPIs, can be attributed to increased vaccine coverage. The high incidence in young people reinforces the importance of vaccination in this age group, a policy that has yet to receive the full support of some sectors of society. FUNDING: UK Medical Research Council, Foundation for the Advancement of Science of the State of Rio de Janeiro, National Council for Scientific and Technological Development

    The role of children in household transmission of SARS-CoV-2 across four waves of the pandemic.

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    BACKGROUND: It is important to understand the dynamics of SARS-CoV-2 transmission in close-contact settings such as households. We hypothesized that children would most often acquire SARS-CoV-2 from a symptomatic adult caregiver. METHODS: This prospective cohort study was conducted from April 2020 to July 2022 in a low-resource, urban settlement in Brazil. We recruited families who brought their children to a public clinic. We collected nasopharyngeal and oral swabs from household members and tracked symptoms and vaccination. RESULTS: In total, 1,256 participants in 298 households were tested for SARS-CoV-2. A total of 4073 RT-PCR tests were run with 893 SARS-CoV-2 positive results (21.9%). SARS-CoV-2 cases were defined as isolated cases (n=158) or well-defined transmission events (n=175). The risk of household transmission was lower if the index case was a child (OR: 0.3 [95% CI: 0.16-0.55], p<0.001) or was vaccinated (OR: 0.29 [95%CI: 0.1-0.85], p=0.024), and higher if the index was symptomatic (OR: 2.53 [95% CI: 1.51-4.26], p<0.001). The secondary attack rate for child index cases to child contacts was 0.29, whereas the secondary attack rate from adult index cases to child contacts was 0.47 (p=0.08). CONCLUSIONS: In this community, children were significantly less infectious to their household contacts than adolescents or adults. Most children were infected by a symptomatic adult, usually their mother. There was a double benefit of vaccination as it protected the vaccinee from severe illness and prevented onward transmission to household contacts. Our findings may also be valid for similar populations throughout Latin America

    Seroprevalence of Chikungunya virus and living conditions in Feira de Santana, Bahia-Brazil.

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    BACKGROUND: Chikungunya is an arbovirus, transmitted by Aedes mosquitoes, which emerged in the Americas in 2013 and spread rapidly to almost every country on this continent. In Brazil, where the first cases were detected in 2014, it currently has reached all regions of this country and more than 900,000 cases were reported. The clinical spectrum of chikungunya ranges from an acute self-limiting form to disabling chronic forms. The purpose of this study was to estimate the seroprevalence of chikungunya infection in a large Brazilian city and investigate the association between viral circulation and living condition. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a population-based ecological study in selected Sentinel Areas (SA) through household interviews and a serologic survey in 2016/2017. The sample was of 1,981 individuals randomly selected. The CHIKV seroprevalence was 22.1% (17.1 IgG, 2.3 IgM, and 1.4 IgG and IgM) and varied between SA from 2.0% to 70.5%. The seroprevalence was significantly lower in SA with high living conditions compared to SA with low living condition. There was a positive association between CHIKV seroprevalence and population density (r = 0.2389; p = 0.02033). CONCLUSIONS/SIGNIFICANCE: The seroprevalence in this city was 2.6 times lower than the 57% observed in a study conducted in the epicentre of the CHIKV epidemic of this same urban centre. So, the herd immunity in this general population, after four years of circulation of this agent is relatively low. It indicates that CHIKV transmission may persist in that city, either in endemic form or in the form of a new epidemic, because the vector infestation is persistent. Besides, the significantly lower seroprevalences in SA of higher Living Condition suggest that beyond the surveillance of the disease, vector control and specific actions of basic sanitation, the reduction of the incidence of this infection also depends on the improvement of the general living conditions of the population

    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

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    Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study