Synthesis of <i>N</i>,<i>O</i>‑Spiroacetals and α‑Arylfurans via Pd-Catalyzed Aerobic Oxidative 2,5-Aminoarylation and α‑Arylation of <i>N</i>‑[3-(2-Furanyl)propyl]‑<i>p</i>‑toluenesulfonamides with Boronic Acids

Unsaturated <i>N</i>,<i>O</i>-spiroacetals and α-arylfurans were synthesized via palladium-catalyzed aerobic oxidative coupling reactions between <i>N</i>-[3-(2-furanyl)­propyl]-<i>p</i>-toluene­sulfonamides and boronic acids, with KF and KOAc as the respective additives. These reactions involve an unprecedented dearomatizing 2,5-aminoarylation and a direct α-arylation of furan rings, respectively, with O₂ as the terminal oxidant

Photoinduced Pd-Catalyzed Dearomative 2,5-Difunctionalizition of Furans via Cascade C–C/C–O Bond Formation

We report an efficient and mild approach for radical dearomatization via photoinduced palladium-catalyzed reaction of three components (i.e., furans, alcohols, and bromoalkanes). In this strategy, various functionalized spiro-heterocycles were prepared from furans in one step via cascade C–C/C–O bond formation under redox neutral conditions