Measuring Sin^22\theta_13 with the Daya Bay Nuclear Reactors

Angle \theta_13 is one of the two unknown neutrino mixing parameters to be determined. Its value may determine the future trend of the neutrino physics. We propose to measure sin^22\theta_13 with a sensitivity better than 0.01 (90% C.L) at the Daya Bay reactor power plant.Comment: 4 pages, 6 figures, talk given at ICHEP06, Moscow, July 26-Aug.2, 200

Physics of tau and charm

The physics of tau and charm started in early 70's after J/$\psi$ and $\tau$ were discovered. Since then several dedicated accelerators and experiments were built with increasing luminosities and studies on light hadron spectroscopy, charmonium, electroweak and QCD were never interupted. New interests and surprises are not rare in this area. With the newly built BEPCII/BESIII, an even brighter future is foreseen.Comment: 12 pages, 17 figures, 4 tables, proceeding for LP0

Neutrino Masses and Flavor Oscillations

This essay is intended to provide a brief description of the peculiar properties of neutrinos within and beyond the standard theory of weak interactions. The focus is on the flavor oscillations of massive neutrinos, from which one has achieved some striking knowledge about their mass spectrum and flavor mixing pattern. The experimental prospects towards probing the absolute neutrino mass scale, possible Majorana nature and CP-violating effects will also be addressed.Comment: 25 pages, 10 figures. An invited contribution to the book entitled "The Standard Theory up to the Higgs discovery - 60 years of CERN" (to be published by World Scientific

Experimental Requirements to Determine the Neutrino Mass Hierarchy Using Reactor Neutrinos

This paper presents experimental requirements to determine the neutrino mass hierarchy using reactor neutrinos. The detector shall be located at a baseline around 58 km from the reactor(s) to measure the energy spectrum of electron antineutrinos ($\bar{\nu}_e$) precisely. By applying Fourier cosine and sine transform to the L/E spectrum, features of the neutrino mass hierarchy can be extracted from the $|\Delta{m}^2_{31}|$ and $|\Delta{m}^2_{32}|$ oscillations. To determine the neutrino mass hierarchy above 90% probability, requirements to the baseline, the energy resolution, the energy scale uncertainty, the detector mass and the event statistics are studied at different values of $\sin^2(2\theta_{13})$Comment: Update Fig.

Recent Results of non-accelarator-based neutrino experiments

Recent results of non-accelerator-based experiments, including those of solar, atmospheric, and reactor neutrinos oscillations, neutrinoless double-beta decays, and neutrino magnetic moments, are reviewed. Future projects and their respective prospects are summarized.Comment: V.2, minor changes with one more reference added. Plenary talk given at the "32nd International Conference on High Energy Physics", Aug. 16-22, 2004, Beijing, P.R. Chin

Exploring the Design Space of Immersive Urban Analytics

Recent years have witnessed the rapid development and wide adoption of immersive head-mounted devices, such as HTC VIVE, Oculus Rift, and Microsoft HoloLens. These immersive devices have the potential to significantly extend the methodology of urban visual analytics by providing critical 3D context information and creating a sense of presence. In this paper, we propose an theoretical model to characterize the visualizations in immersive urban analytics. Further more, based on our comprehensive and concise model, we contribute a typology of combination methods of 2D and 3D visualizations that distinguish between linked views, embedded views, and mixed views. We also propose a supporting guideline to assist users in selecting a proper view under certain circumstances by considering visual geometry and spatial distribution of the 2D and 3D visualizations. Finally, based on existing works, possible future research opportunities are explored and discussed.Comment: 23 pages,11 figure

MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase

Nicotinamide phosphoribosyltransferase (NAMPT) upregulation in human pulmonary artery endothelial cells (hPAECs) is associated with pulmonary arterial hypertension (PAH) progression and pulmonary vascular remodeling. The underlying mechanisms regulating NAMPT expression are still not clear. In this study, we aimed to study the regulation of NAMPT expression by microRNA410 (miR410) in hPAECs and explore the role of miR410 in the pathogenesis of experimental pulmonary hypertension. We show that miR410 targets the 3' UTR of NAMPT and that, concomitant with NAMPT upregulation, miR410 is downregulated in lungs of mice exposed to hypoxia-induced pulmonary hypertension (HPH). Our results also demonstrate that miR410 directly inhibits NAMPT expression. Overexpression of miR410 in hPAECs inhibits basal and VEGF-induced proliferation, migration and promotes apoptosis of hPAECs, while miR410 inhibition via antagomirs has the opposite effect. Finally, administration of miR410 mimics in vivo attenuated induction of NAMPT in PAECs and prevented the development of HPH in mice. Our results highlight the role of miR410 in the regulation of NAMPT expression in hPAECs and show that miR410 plays a potential role in PAH pathobiology by targeting a modulator of pulmonary vascular remodeling