344 research outputs found
N-(1-Acetyl-5-benzoyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzamide
In the molecule of the title compound, C21H18N4O3, the fused pyrrolo[3,4-c]pyrazole ring system is approximately planar [maximum deviation = 0.0486 (16) Å] and forms dihedral angles of 87.21 (8) and 35.46 (7)° with the phenyl rings. In the crystal, N—H⋯O and C—H⋯O hydrogen bonds and weak C—H⋯π interactions link the molecules into chains parallel to [201]
Noise in Genotype Selection Model
We study the steady state properties of a genotype selection model in
presence of correlated Gaussian white noise. The effect of the noise on the
genotype selection model is discussed. It is found that correlated noise can
break the balance of gene selection and induce the phase transition which can
makes us select one type gene haploid from a gene group.Comment: 8 pages, 4 figure
3-(5-Chloronaphthalene-1-sulfonamido)-2-(2-hydroxyethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-5-ium chloride
In the cation of the title compound, C18H20ClN4O3S+·Cl−, the tetrahydropyridinium ring assumes a half-chair conformation. The dihedral angle between the pyrazole ring and the naphthalene ring system is 75.19 (6)°. In the crystal, ions are linked into a three-dimensional network by N—H⋯O, N—H⋯Cl and O—H⋯Cl hydrogen bonds and weak π–π stacking interactions with centroid–centroid distances of 3.608 (2) Å
Evaluation of post hysterectomy vaginal cuff related complications and their management after different modes of hysterectomy
Background: Aim: To update the incidence of vaginal cuff related complications after different modes of hysterectomy and their management.Methods: The study was conducted in Jingzhou central hospital, Jingzhou, Hubei, China. Patient’s case files were reviewed who had undergone Hysterectomy from 1st Jan. 2013 - 31st Dec. 2014. The incidence of vaginal cuff related complications were retrospectively evaluated by different approaches. Data were collected according to our inclusion criteria and statistically analyzed its significance (P <0.05).Results: 887 patients underwent hysterectomy during 2 years of study period. Mean age was 54 ± 4 years. Overall incidence of vaginal cuff related complications were 34 (3.83%) which included vaginal cuff bleeding 12 (1.35%), vaginal cuff infections 16 (1.80%) and vaginal cuff dehiscence 6 (0.67%) without evisceration. Laparoscopic hysterectomy had higher incidence (6.12%), than open abdominal (2.56%) and vaginal (3.22%) hysterectomy. Incidences were significant (P = 0.032) to approaches of hysterectomy. The Incidence of vaginal cuff dehiscence between Laparoscopic and Open abdominal hysterectomy were significant (P = 0.015) but the incidence of vaginal cuff bleeding (P = 0.90) and vaginal cuff infection (P = 0.74) were not significant. Over all incidences were higher in malignancy (61%) than benign (20%).Conclusions: Study suggests that vaginal cuff bleeding, cuff infection, cuff dehiscence and evisceration are rare but not negligible which may lead into catastrophic conditions. Early diagnosis and appropriate management reduces further complications. Partial cuff dehiscence can be managed conservatively without surgical repair with satisfactory outcome
Bis[4-(2-hydroxybenzylideneamino)benzoato-κO 1]tetrakis(methanol-κO)cadmium
In the title mononuclear complex, [Cd(C14H10NO3)2(CH3OH)4], the Cd2+ cation is situated on an inversion centre. It exhibits a distorted octahedral coordination, defined by two carboxylate O atoms from two monodentate anions and by four O atoms from four methanol molecules. The crystal structure comprises intramolecular O—H⋯O and O—H⋯N, and intermolecular O—H⋯O hydrogen bonds. The latter help to construct a layered structure extending parallel to (100)
Current Reversals in a inhomogeneous system with asymmetric unbiased fluctuations
We present a study of transport of a Brownian particle moving in periodic
symmetric potential in the presence of asymmetric unbiased fluctuations. The
particle is considered to move in a medium with periodic space dependent
friction. By tuning the parameters of the system, the direction of current
exhibit reversals, both as a function of temperature as well as the amplitude
of rocking force. We found that the mutual interplay between the opposite
driving factors is the necessary term for current reversals.Comment: 9 pages, 7 figure
BrushNet: A Plug-and-Play Image Inpainting Model with Decomposed Dual-Branch Diffusion
Image inpainting, the process of restoring corrupted images, has seen
significant advancements with the advent of diffusion models (DMs). Despite
these advancements, current DM adaptations for inpainting, which involve
modifications to the sampling strategy or the development of
inpainting-specific DMs, frequently suffer from semantic inconsistencies and
reduced image quality. Addressing these challenges, our work introduces a novel
paradigm: the division of masked image features and noisy latent into separate
branches. This division dramatically diminishes the model's learning load,
facilitating a nuanced incorporation of essential masked image information in a
hierarchical fashion. Herein, we present BrushNet, a novel plug-and-play
dual-branch model engineered to embed pixel-level masked image features into
any pre-trained DM, guaranteeing coherent and enhanced image inpainting
outcomes. Additionally, we introduce BrushData and BrushBench to facilitate
segmentation-based inpainting training and performance assessment. Our
extensive experimental analysis demonstrates BrushNet's superior performance
over existing models across seven key metrics, including image quality, mask
region preservation, and textual coherence
Diaquabis(2-methyl-1H-imidazol-3-ium-4,5-dicarboxylato-κ2 O,O′)magnesium
The title compound, [Mg(C6H5N2O4)2(H2O)2], was prepared by reaction of Mg(NO3)2 and 2-methyl-1H-imidazole-4,5-dicarboxylic acid under hydrothermal conditions. The MgII atom lies on an inversion centre and displays a distorted octahedral coordination geometry. An extended three-dimensional network of intermolecular O—H⋯O and N—H⋯O hydrogen bonds stabilizes the crystal structure
5-tert-Butyl 1-ethyl 3-amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate
The asymmetric unit of the title compound, C13H20N4O4, contains two crystallographically independent molecules in which the dihedral angles between the fused pyrrole and pyrazole rings are 5.06 (8) and 1.12 (8)°. In the crystal, molecules are linked by intermolecular N—H⋯O and N—H⋯N hydrogen bonds into chains parallel to the b axis
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