45,025 research outputs found

    Ocean shrimp report 1972 season

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    California's 1972 ocean shrimp landings totaled 2,488,683 pounds, a decrease of 585,857 pounds from the 1971 season when 3,074,540 pounds were landed. The decrease resulted primarily from the failure of the vessels to reach the quotas in Areas A, B-1 and B-2. (18pp.

    Low Molecular Weight mRNA Encodes a Protein That Controls Serotonin 5-HT_(1c) and Acetylcholine M_1 Receptor Sensitivity in Xenopus Oocytes

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    Serotonin 5-HT_(1c) and acetylcholine M_1 receptors activate phosphoinositidase, resulting in an increased formation of IP_3 and 1,2 diacylglycerol. In Xenopus oocytes injected with mRNA encoding either of these receptors, Ca^(2+) released from intracellular stores in response to IP3 then opens Ca^(2+)-gated Cl^-channels. In the present experiments, oocytes expressing a transcript from a cloned mouse serotonin 5-HT_(1c) receptor were exposed to identical 15-s pulses of agonist, administered 2 min apart; the second current response was two to three times that of the first. However, in those oocytes coinjected with the 5-HT_(1c) receptor transcript and a low molecular weight fraction (0.3-1.5 kb) of rat brain mRNA, the second current response was ~50% of the first. Thus, the low molecular weight RNA encodes a protein (or proteins) that causes desensitization. Experiments using fura-2 or a Ca^(2+)-free superfusate indicated that desensitization of the 5-HT_(1c) receptor response does not result from a sustained elevation of intracellular Ca^(2+) level or require the entry of extracellular Ca^(2+). Photolysis of caged IP_3 demonstrated that an increase in IP_3 and a subsequent rise in Ca^(2+) do not produce desensitization of either the IP_3 or 5-HT_(1c) peak current responses. Furthermore, in oocytes coinjected with the low molecular weight RNA and a transcript from the rat M_1 acetylcholine receptor, the M_1 current response was greatly attenuated. Our data suggest that the proteins involved in attenuation of the M_1 current response and desensitization of the 5-HT_(1c) current response may be the same

    Recovery operators, paraconsistency and duality

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    There are two foundational, but not fully developed, ideas in paraconsistency, namely, the duality between paraconsistent and intuitionistic paradigms, and the introduction of logical operators that express meta-logical notions in the object language. The aim of this paper is to show how these two ideas can be adequately accomplished by the Logics of Formal Inconsistency (LFIs) and by the Logics of Formal Undeterminedness (LFUs). LFIs recover the validity of the principle of explosion in a paraconsistent scenario, while LFUs recover the validity of the principle of excluded middle in a paracomplete scenario. We introduce definitions of duality between inference rules and connectives that allow comparing rules and connectives that belong to different logics. Two formal systems are studied, the logics mbC and mbD, that display the duality between paraconsistency and paracompleteness as a duality between inference rules added to a common core– in the case studied here, this common core is classical positive propositional logic (CPL + ). The logics mbC and mbD are equipped with recovery operators that restore classical logic for, respectively, consistent and determined propositions. These two logics are then combined obtaining a pair of logics of formal inconsistency and undeterminedness (LFIUs), namely, mbCD and mbCDE. The logic mbCDE exhibits some nice duality properties. Besides, it is simultaneously paraconsistent and paracomplete, and able to recover the principles of excluded middle and explosion at once. The last sections offer an algebraic account for such logics by adapting the swap-structures semantics framework of the LFIs the LFUs. This semantics highlights some subtle aspects of these logics, and allows us to prove decidability by means of finite non-deterministic matrices

    A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria

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    The novel genetic method of "sheltered RIP" (repeat induced point mutation) was used to generate a Neurospora crassa mutant in which MOM19, a component of the protein import machinery of the mitochondrial outer membrane, can be depleted. Deficiency in MOM19 resulted in a severe growth defect, but the cells remained viable. The number of mitochondrial profiles was not grossly changed, but mutant mitochondria were highly deficient in cristae membranes, cytochromes, and protein synthesis activity. Protein import into isolated mutant mitochondria was decreased by factors of 6 to 30 for most proteins from all suborganellar compartments. Proteins like the ADP/ATP carrier, MOM19, and cytochrome c, whose import into wild-type mitochondria occurs independently of MOM19 became imported normally showing that the reduced import activities are solely caused by a lack of MOM19. Depletion of MOM19 reveals a close functional relationship between MOM19 and MOM22, since loss of MOM19 led to decreased levels of MOM22 and reduced protein import through MOM22. Furthermore, MOM72 does not function as a general backup receptor for MOM19 suggesting that these two proteins have distinct precursor specificities. These findings demonstrate that the import receptor MOM19 fulfills an important role in the biogenesis of mitochondria and that it is essential for the formation of mitochondria competent in respiration and phosphorylation

    Mixing ratios of trace gases in the austral polar atmosphere during August and September of 1987

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    Mixing ratios are presented for a number of long-lived trace gases in the austral polar atmosphere during August and September of 1987. The recent discovery of a 12-year trend of increasing depletion of ozone over the Antarctic Continent in the spring of each year led to numerous theoretical interpretations and several scientific expeditions to the region. The results herein were obtained as part of a major effort involving penetration of the region of ozone depletion by NASA's multi-instrumented aircraft. One of the 14 instruments on the high-altitude ER-2 aircraft collected pressurized air samples between latitudes of 53 degrees and 72 degrees south at pressure altitudes up to 21 km in a series of 12 flights from Punta Arenas, Chile, over the Palmer Peninsula. The sampling system, located in the nose section of ER-2, has an inlet tube in the free airstream, a metal-bellows air pump, and 14 specially treated 1.6 l stainless-steel canisters for containing the pressurized air at 350 kPa. A typical flight profile consisted of a southbound path on the 428 K potential temperature surface, a descent to a pressure altitude of 13.7 km, a climb to the 460 K surface, and return on this surface. Mixing ratios for the trace gases were obtained from gas chromatographic analyses of the pressurized air samples. Of the species measured, the mixing ratios for CH4, CO, N2O, CF2 Cl2, CFCl3, CH3, CCl3, CCl4, and C2F3Cl3 are reported here

    Reduced Order Modeling for Transonic Aeroservoelastic Control Law Development

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    As aircraft become more flexible, aeroelastic considerations become increasingly important and complex, particularly for transonic flight where nonlinearities in the flow render linear analysis tools less effective. In order to analyze these aeroelastic interactions between the fluid and the structure efficiently, reduced order models (ROMs) are sometimes generated from and used in place of computational fluid dynamics solutions. In this paper, several aerodynamic ROMs are generated and coupled with structural models to form aeroelastic ROMs. The aerodynamic ROMs generated here include the effects of control surface motion. Hence, the aeroelastic ROMs presented here are appropriate for use in aeroservoelastic applications and are intended to be used for aeroservoelastic control law development. These ROMs are used to simulate a number of test cases with and without control surface involvement. Results show that several of the ROMs generated in the paper are able to predict results similar to solutions of higher-order computational methods

    Subcooled flow boiling of fluorocarbons

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    A study was conducted of heat transfer and hydrodynamic behavior for subcooled flow boiling of Freon-113, one of a group of fluorocarbons suitable for use in cooling of high-power-density electronic components. Problems arising from the excellent wetting characteristics and large solubility constants of fluorocarbons were also examined. The primary configuration was vertical upflow through a 0.500-in. ID stainless steel tube with direct resistance heating of the tube wall. Operating parameter ranges included up to 4.28 ft/sec velocity, 22.3 psia pressure, 61*F subcooling, 0.40 void fraction, 1.08 X 10-3 moles/mole dissolved gas, and 105 Btu/hr ft2 heat flux. Single-phase heat transfer was adequately correlated by standard methods. Boiling curves had a unique form dominated by large, discontinuous jumps in wall temperature at the incipient point on increasing heat flux traverses. Effects of velocity and subcooling on two-phase heat transfer followed conventional trends. Techniques were devised for accurate determination of the temperature dependence of the air-Freon-113 solubility constant and for measurement and control of dissolved gas content in the main loop. Dissolved gas effects were found to increase heat transfer significantly in the partial boiling mode. Data in the fully-developed boiling mode were successfully described by modifications of existing correlations. A conventional correlation provided, at best, an upper bound for the critical heat flux data. Models and analyses were formulated for predicting delayed nucleation and dissolved gas effects on incipience. Delayed nucleation and hysteresis were successfully eliminated by means of a special surface coating. Transition in gassy boiling heat transfer from gas-dominated to vapor-dominated modes was postulated with reference to adjusted saturation temperatures.(cont.) Single-phase pressure drop was adequately correlated by standard methods. Parametric effects on two-phase total pressure drop were investigated and described. Three novel techniques--photographic, trap, and capacitance-- were employed to obtain accurate void fraction measurements. It was found that dissolved gas drastically retarded bubble collapse rates. Parametric effects on void fraction were examined and approximately correlated on quality coordinates. Modification of an existing analysis for predicting the point of net vapor generation gave reasonable agreement with void data. Void information was used to estimate the gravity component of pressure drop. The remaining friction-acceleration component data were plotted on coordinates suggested in an existing correlation. Alteration of the coordinates to account for issolved gas resulted in fair agreement of data with the correlation curv-. A qualitative description of the gas-dominated to vapor-dominated transition in pressure drop performance, analogous to that for heat transfer, was developed.DSR Project
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