22 research outputs found

    Effect of various pre-harvest treatments on shelf life and morphological characteristics of fruits of mango (Mangifera indica L.) var. ‘Amrapali’

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    The mango is considered as ‘king of fruits’ in India due to its delicious taste and nutritional status. Extension of fruit shelf life is a prime importance for availability of fresh fruit in market for longer duration and distance transportation. India is the largest producer and a prominent exporter of mango in the world.In this context, the study was conducted to evaluate the effect of preharvest spray of different chemicals and plant growth regulators (PGRs) on mango var. ‘Amrapali’ for shelf life and its quality. As ‘Amrapali’ has regular bearer with very good flavor and taste with a late maturing character, selected for shelf life studies. The fruits of mango weresprayed with chemicals viz. CaCl2 1%, CaCl2 2%, Ca(NO3)2 1%, Ca(NO3)2 2%, KNO3 1%, KNO3 2%, GA3 25 mg/l, GA3 50 mg/l, Ethrel 0.1 ml/l and Ethrel 0.2 ml/l prior to harvest. After harvesting, fruits were stored under ambient storage condition. Among all the treatments, GA3 25 mg/l treatment recorded significantly highest fruit length, fruit diameter, fruit volume and fruit weight at harvest and at fully ripe stage. Application of CaCl22% resulted in significantly minimum physiological loss in weight consistently from 2nd day to 16th day of storage besides significantly highest shelf life and quality. Hence, this intervention can contribute in preserving physical and chemical quality attributes for maximum acceptance by consumers

    Pulmonary Capillary Hemangiomatosis: A Rare Cause of Pulmonary Arterial Hypertension, Presenting as Supraventricular Tachycardia

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    With a prevalence of less than 1/million, Pulmonary Capillary Hemangiomatosis is a rare disorder of capillary proliferation in the alveolar septae leading to pulmonary arterial hypertension and mimics pulmonary veno-occlusive disease

    Investigating the Association Between Serum Vitamin D Deficiency and Idiopathic Benign Paroxysmal Positional Vertigo

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    Background: It is suggested that there is a positive association between vitamin D deficiency and benign paroxysmal positional vertigo (BPPV). We suggest, as a hypothesis, there is a positive association between vitamin D deficiency and BPPV. The current study aimed to investigate the association between vitamin D levels and BPPV.Methods: The present observational case-control study was planned and conducted on 100 participants (50 cases and 50 controls) in the Department of Neurology, Choithram Hospital & Research Center (CHRC), Indore, MP, India, from January 2018 to December 2018. All consecutive patients with diagnosis of idiopathic BPPV who were above the age of 18 years with a negative neurological status were included. Analyses were performed using SPSS software version 10. Results: BPPV was more common among those aged 50 to 70 years (64%). Out of 100 participants, 72 (72%) had vitamin D deficiency, in which 40 (80%) were cases and 32 (64%) were controls. 32 (64%) patients had posterior canal involved, out of them 20 (40%) were females and 12 (24%) were males, and in both groups posterior canal was more involved. Canal involvement according to gender was not statistically significant (P value=0.45). Mean vitamin D level for cases and controls was 34.9 and 46.5 nmol/L, respectively, and this difference was statically very significant with a p-value of 0.01 (P value < 0.05).Conclusion: According to the findings, there is a statistically significant association between vitamin D3 deficiency and Idiopathic BPPV. It can be noted that vitamin D3 deficiency may be a risk factor for the BPPV

    Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells.

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    Plasma membrane tension regulates many key cellular processes. It is modulated by, and can modulate, membrane trafficking. However, the cellular pathway(s) involved in this interplay is poorly understood. Here we find that, among a number of endocytic processes operating simultaneously at the cell surface, a dynamin independent pathway, the CLIC/GEEC (CG) pathway, is rapidly and specifically upregulated upon a sudden reduction of tension. Moreover, inhibition (activation) of the CG pathway results in lower (higher) membrane tension. However, alteration in membrane tension does not directly modulate CG endocytosis. This requires vinculin, a mechano-transducer recruited to focal adhesion in adherent cells. Vinculin acts by controlling the levels of a key regulator of the CG pathway, GBF1, at the plasma membrane. Thus, the CG pathway directly regulates membrane tension and is in turn controlled via a mechano-chemical feedback inhibition, potentially leading to homeostatic regulation of membrane tension in adherent cells

    Modelling challenges of blockchain technology enabled healthcare sustainable supply chain management: a modified-total interpretive structural modelling approach

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    Blockchain technology (BCT) is beneficial for the Healthcare Sustainable Supply Chain (HSSC), and the adoption of this technology provides many benefits improving the performance of the supply chain, effortless information sharing, mitigation of data modification, etc. On the contrary, this study focuses on the various challenges that come in the path while adopting the BCT. For this, the present study initially identified the multiple challenges from the in-depth literature review. Then, the Delphi method was applied for further analysis and scalability of each challenge. Afterward, Modified-Total Interpretive Structural Modeling (M-TISM) approach is used for identifying the criticality of challenges based on the classification of challenges into different levels. This operation provides the driving and dependence power of each challenge.Furthermore, MICMAC (Cross-Impact Matrix Multiplication Analysis) analysis was performed. At the end of the analysis, the authors found the six critical challenges related to the adoption of BCT in the Healthcare Sustainable Supply Chain (HSSC). These critical challenges are the Economical Challenge (C3), Stakeholder commitment and careful handling of BCT (C2), Combining SSCM practices to BCT(C7), Lack of government intentions to promote BCT in SCM (C6), Data Security threat (C1) and Poor infrastructure for the adoption of BCT (C4). The stakeholders of HSSC should make an effort to control them on a priority basis. In addition to this, the authors also provided the practical implication of the study and future research direction for better adoption of BCT in the Healthcare Sustainable Supply Chain