Characteristics of the malignant transformed cases.

<p>M, Male; F, Female; BM, Buccal mucosa; T, Tongue; G, Gingival buccal sulcus. P, Present; A, Absent.</p><p>Characteristics of the malignant transformed cases.</p

Immunohistochemical expression of FGF-2, FGFR-2 and FGFR-3 in OSCC and PMOLs.

<p>Immunohistochemical expression of FGF-2, FGFR-2 and FGFR-3 in OSCC and PMOLs.</p

Gene expression profile of <i>FGF-2</i>, <i>FGFR-2</i> & <i>FGFR-3</i> by Quantitative Real—time PCR.

<p>Gene expression profile of <i>FGF-2</i>, <i>FGFR-2</i> & <i>FGFR-3</i> by Quantitative Real—time PCR.</p

Association of FGF-2, FGFR-2 and FGFR-3 with clinico-pathological features in OSCC.

<p>Association of FGF-2, FGFR-2 and FGFR-3 with clinico-pathological features in OSCC.</p

Immunohistochemical staining of FGFR-2 (A-C).

<p>A, FGFR-2 positivity in transformed cases of Leukoplakia with dysplasia X 200. B, FGFR-2 positivity in transformed case of OSMF in fibrosis area X 100. C, FGFR-2 positivity in OSCC X 100.</p

Real time PCR results of FGF-2, FGFR-2 and FGFR-3 and frequency of FGF-2, FGFR-2 and FGFR-3 malignant transformation rate (A-D).

<p>Bar diagram showing fold change expression of FGF-2, FGFR-2 and FGFR-3 by Real Time. <b>A</b>, PCR in OSMF, LKP, OSCC and healthy controls. B, Frequency of FGF-2 malignant transformation rate in PMOLs. C, Frequency of FGFR-2 malignant transformation rate in PMOLs. D, Frequency of FGFR-3 malignant transformation rate in PMOLs.</p

Logistic regression analysis of variables in PMOLs malignant transformation.

<p>OR, Odds ratio; 95%CI, 95% confidence interval.</p><p>Logistic regression analysis of variables in PMOLs malignant transformation.</p

MOESM3 of Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites

Additional file 3. GO analysis using software DAVID for the 76 genes corresponding to 191 UCHL1 peaks. The percentage (%) of the input gene count within the term group was calculated. Fold enrichment is the ratio of percentage of user’s genes in a term group versus the percentage of the term genes in human genome (population background). The p value was calculated by a modified Fisher’s exact test (EASE score). FDR is the false discovery rate

Patients characteristic of malignant transformed and untransformed cases in PMOLS.

<p>Patients characteristic of malignant transformed and untransformed cases in PMOLS.</p

MOESM4 of Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites

Additional file 4. In situ PLA images of negative controls used in PLA assays