45 research outputs found

    Study and development of custom ‚Äúserious games‚ÄĚ for patients and users

    Get PDF
    Video games are part of our culture and permeate several segments of society, from casual entertainment to serious purposes. This research work focuses on the latter, more specifically on the use of Serious Games in the healthcare context. In this sense, Serious Games have been researched through clinical studies, implemented to improve several conditions and have already proved to be efficient and valid, especially due to their ability to captivate and motivate the patient. With this in mind, this research explored the use of Serious Games for physical rehabilitation of stroke impaired patients and how this approach could be implemented in the Portuguese healthcare system. The research started with a thorough literature review of the validity and effectiveness of the use of Serious Games for this type of patients. Then, through surveys and interviews with healthcare professionals and game developers, the main barriers to the implementation and development of Serious Games for physical rehabilitation were accessed. Posteriorly, the feasibility of implementing a business model for this specific niche (in Portugal) was evaluated through a market analysis, abridging social, economic, political and technological aspects that culminated in the design of several hypothetical scenarios that envisioned the possibility of making this approach work. This research allowed to achieve an understanding of what needs to be overcome in order for this technique to be successful: Serious Games are still widely unknown among healthcare professionals and there is an underlying stigma against video games that clouds the possible benefits of using Serious Games. Moreover, the social context of future users will also determine their acceptance and compliance. Nevertheless, the research has evidenced that the implementation of this paradigm is economically viable as it would indirectly allow the monetization of rehabilitation therapies by making them available to a larger slice of the disabled population, which is of utmost importance, mainly during the times we currently live in.Os videojogos fazem parte da nossa cultura e permeiam v√°rios segmentos da sociedade, desde entretenimento casual at√© prop√≥sitos mais s√©rios. Este trabalho de investiga√ß√£o concentra-se na segunda op√ß√£o ‚Äď mais especificamente, no uso de Serious Games no contexto da sa√ļde. Neste sentido, os Serious Games t√™m sido investigados atrav√©s de estudos cl√≠nicos, implementados para melhorar diversas condi√ß√Ķes e patologias e j√° provaram ser eficientes e v√°lidos, principalmente gra√ßas √† sua capacidade de motivar e cativar o paciente. Tendo isto em conta, esta investiga√ß√£o explorou o uso dos Serious Games para reabilita√ß√£o f√≠sica de pacientes p√≥s-AVC e de que forma √© que esta abordagem poderia ser implementada no Servi√ßo Nacional de Sa√ļde. A investiga√ß√£o come√ßou com uma revis√£o bibliogr√°fica completa da validade e efic√°cia do uso de Serious Games para este tipo de pacientes. De seguida, atrav√©s de question√°rios e entrevistas a profissionais de sa√ļde e desenvolvedores de videojogos, as principais barreiras para implementa√ß√£o e desenvolvimento de Serious Games para reabilita√ß√£o f√≠sica foram levantadas. Posteriormente, a viabilidade de executar um business plan para esse nicho espec√≠fico (em Portugal) foi avaliada atrav√©s de uma an√°lise de mercado, abrangendo aspetos sociais, econ√≥micos, pol√≠ticos e tecnol√≥gicos, que culminou no desenho de v√°rios cen√°rios hipot√©ticos que previam a possibilidade de fazer com que este paradigma se tornasse poss√≠vel e funcional. Este trabalho de investiga√ß√£o permitiu atingir uma compreens√£o daquilo que necessita de ser ultrapassado para que esta abordagem tenha sucesso: os Serious Games ainda s√£o amplamente desconhecidos entre os profissionais de sa√ļde e existe um estigma subjacente aos videojogos que obscurece os poss√≠veis benef√≠cios do seu uso. Para al√©m disso, o contexto social dos futuros utilizadores tamb√©m ir√° determinar a sua aceita√ß√£o e ades√£o. No entanto, esta investiga√ß√£o evidenciou que a implementa√ß√£o deste modelo √© economicamente vi√°vel, pois iria permitir, de uma forma indireta, a rentabiliza√ß√£o de terapias de reabilita√ß√£o ao fazer com que estas fossem acess√≠veis a uma fatia mais larga da popula√ß√£o debilitada, o que √© de extrema import√Ęncia, principalmente nos dias de hoje

    Review: Playing at a Distance - Borderlands of Videogame Aesthetic

    Get PDF
    Sonia Fizek's Playing at Distance: Borderlands of Video Game Aesthetic navigates the intricate intersection of digital technology, aesthetics, and play in the context of video games, challenging conventional ideas of player agency. This critical recension delves into the book's contributions, highlighting its innovative exploration of mediated distance, interactivity, delegation, automation, ambience, spectacle, and the evolving nature of player engagement. While acknowledging its theoretical depth, this review emphasizes the book's significance in reshaping our understanding of video game aesthetics and the complex relationship between humans, machines, and digital play

    Understanding anime - visual iconography as a mirror of Japanese culture

    Get PDF
    Anime is commonly known as a Japanese animation style pervaded with a particular visual language and iconography that is frequently used to convey emotions, thoughts, feelings, moods or needs ‚Äď in short, subtext. In order to get a full understanding of anime, it is imperative to become familiar with this non-verbal language. This visual language was born from various elements that shaped Japanese culture, as well as etiquette and how one should express one‚Äôs emotions or innermost thoughts. We will attempt to understand the cultural aspects behind the emergence of this iconography as well as how the Japanese position themselves when it comes to expression of emotions or feelings, and how these beliefs transfer to the non-verbal language of anime, through the analysis of examples of where this iconography is used. We also aim to explore the meaning behind the most common stylized expressions found in anime characters, analyzing a broad range of examples from anime of different genres and three different decades, exploring the way how they have evolved over the years while to trying to understand why they are still relevant nowadays.info:eu-repo/semantics/publishedVersio

    Serious games for physical rehabilitation: aesthetic discrepancies between custom-made serious games and commercial titles used for healthcare

    Get PDF
    Serious games are videogames that are used with purposes that go beyond the mere entertainment of the player. Among their many applications, healthcare is one of the most prominent ones, as serious games can have a wide range of applications within this field. One of the core uses of serious games in this area is for physical rehabilitation of patients. For this purpose, both custom-made serious games as well as commercial entertainment titles, such as those for Nintendo Wii, can be used. However, while custom-made serious games appear to be more clinically effective, patients seem to prefer the gaming experience of playing a commercial title. This paper aims to compare the game goals as well as the aesthetics of Wii Sports (a commercial title commonly used in the context of physical rehabilitation) with the visual aesthetic and goals of custom-made serious games that have obtained clinically significant results in upper limb rehabilitation, in order to try and understand what can be done in terms of videogame graphics and aesthetics to bridge the gap between these two approaches.info:eu-repo/semantics/publishedVersio

    Serious Games for Physical Rehabilitation: Aesthetic discrepancies between custom-made serious games and commercial titles used for healthcare

    Get PDF
    Serious games are videogames that are used with purposes that go beyond the mere entertainment of the player. Among their many applications, healthcare is one of the most prominent ones, as serious games can have a wide range of uses within this field, namely physical rehabilitation of patients. For this purpose, both custom-made serious games and commercial entertainment titles, such as those for Nintendo Wii, can be used. However, while custom-made serious games appear to be more clinically effective, patients seem to prefer the gaming experience of playing a commercial title. This paper aims to compare the game goals and the aesthetics of Wii Sports (a commercial title used in the context of physical rehabilitation) with custom-made serious games that have obtained clinically significant results in upper limb rehabilitation, in order to try and understand what can be done to bridge the gap between these two approaches

    Development and integration of animal-based welfare indicators, including pain, in goat farms in Portugal

    Get PDF
    Tese de Doutoramento em Ci√™ncias Veterin√°rias, especialidade de Cl√≠nicaThe development of species-specific protocols for on-farm welfare assessment represents a major concern for the European Union agricultural policy. Proper welfare assessment demands for the use of valid, reliable and feasible animal-based welfare indicators. The literature and policy-makers recognise the need for advancing knowledge in this area. This thesis aims at developing and integrating animal-based indicators in on-farm welfare assessment protocols, focusing on dairy goat farms. Specifically, this thesis contributes to literature in three areas. First, it contributes to the identification of animal-based welfare indicators that should be included in welfare assessment protocols. We conducted a literature review that allowed for the recognition of the need for future research in the indicators‚Äô psychometric properties, such as reliability and feasibility. Secondly, this thesis develops tools to assist the measurement of body condition and lameness. For body condition, we developed a visual body condition scoring system (BSC). Our approach requires minimum animal handling without compromising a valid and reliable individual assessment of the goats. With respect to lameness we developed a websurvey that allowed us to collect observer‚Äôs ratings of goats lameness condition. Our survey showed that observers were only able to consistently assess severely lame goats, a finding which is important towards the integration of the indicator in assessment protocols. The observers‚Äô ratings also showed that the numerical rating scales should only be used considering their ordinal level of measurement. This directs research towards the development of scoring systems with higher levels of measurement, like the modified visual analogue scales. Third, this thesis contributed to the development of a welfare assessment protocol that integrated and tested the two studied indicators (BCS and lameness). Such protocol was implemented in 30 Portuguese farms and provided insights into the main welfare problems affecting intensively kept dairy goats in our country (claw overgrowth, queuing at feeding, very fat animals), which is paramount to improve dairy goats‚Äô welfare. Research conducted for this thesis has practical implications for both welfare assessment research and to the goat industry in general. Ultimately, through the development of adequate assessment tools, it integrates the welfare issue into the food chain, meeting the consumers‚Äô expectations in the development of a sustainable food production system.RESUMO - Desenvolvimento e integra√ß√£o de indicadores de bem-estar animal, incluindo dor, em explora√ß√Ķes de cabras em Portugal - A elabora√ß√£o de protocolos de avalia√ß√£o de bem-estar espec√≠ficos para cada esp√©cie pecu√°ria √© uma preocupa√ß√£o da pol√≠tica agr√≠cola europeia. A literatura da √°rea de bem-estar animal identifica a cria√ß√£o de instrumentos de medi√ß√£o como o primeiro passo para a elabora√ß√£o destes protocolos. Esta tese tem como objetivo desenvolver e integrar indicadores para incluir em protocolos de avalia√ß√£o para utilizar em explora√ß√Ķes de cabras de aptid√£o leiteira. Esta tese apresenta tr√™s contributos para a literatura de bem-estar animal. Em primeiro lugar, contribui para a identifica√ß√£o de indicadores, baseados nos animais, com potencial para integra√ß√£o em protocolos de avalia√ß√£o. A revis√£o bibliogr√°fica realizada permitiu reconhecer a necessidade premente de investiga√ß√£o nesta √°rea, dado que a maior parte dos indicadores necessitam de ser testados e validados. Em segundo lugar, esta tese desenvolve ferramentas para apoiar a avalia√ß√£o da condi√ß√£o corporal e da claudica√ß√£o. Para a condi√ß√£o corporal foi criado um sistema visual de avalia√ß√£o considerado v√°lido e repet√≠vel, e que apenas necessita de uma breve conten√ß√£o dos animais para ser utilizado. Relativamente √† claudica√ß√£o foram recolhidas participa√ß√Ķes de observadores relativamente √† observa√ß√£o de v√≠deos de cabras com diferentes n√≠veis de claudica√ß√£o. A an√°lise destas observa√ß√Ķes permitiu concluir que os participantes apenas s√£o consistentes a avaliar os casos mais graves de claudica√ß√£o, facto importante para a integra√ß√£o do indicador em protocolos de avalia√ß√£o. As classifica√ß√Ķes dos observadores mostraram ainda que as escalas num√©ricas em uso apenas podem ser utilizadas considerando um n√≠vel ordinal de medi√ß√£o. Este facto abre o caminho para o desenvolvimento de escalas com n√≠veis mais elevados de medi√ß√£o, como as escalas visuais anal√≥gicas modificadas. Em terceiro lugar, esta tese desenvolve um protocolo de avalia√ß√£o que inclui e testa os indicadores condi√ß√£o corporal e claudica√ß√£o. Este protocolo permitiu investigar sobre os maiores problemas de bem-estar que afetam as explora√ß√Ķes intensivas de leite de cabra em Portugal (sobre crescimento das unhas, filas na manjedoura, animais gordos), sendo esta informa√ß√£o fundamental para analisar como melhorar o bem-estar das cabras de leite. A investiga√ß√£o conduzida no √Ęmbito desta tese apresenta implica√ß√Ķes pr√°ticas tanto para o estudo do bem-estar animal, como para a explora√ß√£o de leite de cabra. O desenvolvimento de ferramentas adequadas de avalia√ß√£o permite a integra√ß√£o da valora√ß√£o do bem-estar na cadeia de produ√ß√£o, indo ao encontro das expectativas dos consumidores para a concep√ß√£o de sistemas mais sustent√°veis de produ√ß√£o de alimentos

    Uma sa√ļde global : princ√≠pios da estrat√©gia global de conten√ß√£o de resist√™ncias a agentes antimicrobianos : sua percep√ß√£o e implementa√ß√£o pelos produtores de bovinos de carne do Ribatejo Norte

    Get PDF
    Disserta√ß√£o de Mestrado Integrado em Medicina Veterin√°riaA utiliza√ß√£o de antimicrobianos na produ√ß√£o animal tem sido motivo de intenso debate, pelas preocupa√ß√Ķes sobre possibilidade de transfer√™ncia de bact√©rias a eles resistentes dos animais para o Homem. Foram desenvolvidos programas de monitoriza√ß√£o de resist√™ncias e consumo de antimicrobianos, que demonstram que o desenvolvimento de resist√™ncias pode ser minimizado pela implementa√ß√£o de estrat√©gias para uma utiliza√ß√£o prudente e racional dos antimicrobianos nas explora√ß√Ķes pecu√°rias. O presente estudo constitui uma primeira abordagem para avaliar diversos par√Ęmetros importantes para a utiliza√ß√£o prudente e racional dos antimicrobianos, como os conhecimentos, grau de percep√ß√£o e pr√°ticas dos produtores, para o que foram realizados 185 question√°rios presenciais em explora√ß√Ķes de bovinos de carne da DIV Ribatejo Norte. Os resultados alertam para a necessidade de forma√ß√£o nas √°reas da Biosseguran√ßa/Bioconten√ß√£o e de manuten√ß√£o de registos de utiliza√ß√£o de antimicrobianos nas explora√ß√Ķes. Os m√©dicos veterin√°rios t√™m um papel importante, por serem a principal fonte de informa√ß√£o dos produtores. A informa√ß√£o obtida n√£o nos permitiu avaliar o consumo de antimicrobianos; apenas 11% dos produtores mantinham registos, na sua maioria incompletos, das interven√ß√Ķes metafil√°ticas e terap√™uticas. A alternativa de an√°lise das informa√ß√Ķes das receitas/requisi√ß√Ķes veterin√°rias, tamb√©m n√£o foi vi√°vel, pois apenas 82% das aquisi√ß√Ķes era acompanhada de requisi√ß√£o/receita M√©dico-Veterin√°ria. As √ļltimas quest√Ķes do question√°rio elaborado procuravam conhecer a opini√£o dos respons√°veis pelas explora√ß√Ķes. Deste total, 94% concordavam que a introdu√ß√£o de boas pr√°ticas podia reduzir a utiliza√ß√£o de antimicrobianos, tendo 52% considerado importante esta redu√ß√£o, demonstrando que existe espa√ßo para a redu√ß√£o da utiliza√ß√£o destes medicamentos. Um total de 18% dos produtores n√£o expressou a opini√£o sobre antibiorresist√™ncias, confirmando a necessidade de aumentar o n√≠vel de forma√ß√£o nesta √°rea.ABSTRACT - ‚ÄúOne Health: Global Principles for the Containment of antimicrobial resistance ‚Äď perceived importance and implementation by beef farmers at Ribatejo Norte‚ÄĚ - The use of antimicrobial drugs in livestock farms has been at the center of many debates because of the possibility of resistant bacteria transmission from animals to men. Resistance and antimicrobial consumption monitoring programs have been developed, suggesting that the risks of development of resistant bacteria can be minimized through a prudent and rational use of antimicrobials in livestock farms. This study is a first approach to evaluate several parameters important to the prudent and rational use of antimicrobials, such as farmers‚Äė knowledge, perceived degree of importance and management practices. A total of 185 in-person interviews were conducted in beef farms of the DIV Ribatejo Norte in Portugal. Results alert for the need to further educate farmers in Biosecurity/Biocontainment and to keep registries of antimicrobials in the farms. Veterinarians play an important role, for being the main source of information. The information obtained did not allow for an evaluation of antimicrobial consumption; only 11% of the farmers kept records, largely incomplete, of metaphylactic and therapeutic treatments. The alternative of collecting data on veterinary prescriptions was also not viable, since only 82% of purchased drugs were sanctioned by a veterinarian. The last two questions elicited the farm manager ‚Äóopinions. From this total, 94% agreed that good management practices could reduce the antimicrobial usage in their farms; furthermore, 52% agreed that this reduction was important, showing that such reduction could be achieved. A total of 18% of the farmers did not have an opinion on antimicrobial resistance, confirming the requirements for further education in this area

    Green spaces are not all the same for the provision of air purification and climate regulationservices: the case of urban parks

    Get PDF
    The growing human population concentrated in urban areas lead to the increase of road traffic and artificial areas, consequently enhancing air pollution and urban heat island effects, among others. These environmental changes affect citizen's health, causing a high number of premature deaths, with considerable social and economic costs. Nature-based solutions are essential to ameliorate those impacts in urban areas. While the mere presence of urban green spaces is pointed as an overarching solution, the relative importance of specific vegetation structure, composition and management to improve the ecosystem services of air purification and climate regulation are overlooked. This avoids the establishment of optimized planning and management procedures for urban green spaces with high spatial resolution and detail. Our aim was to understand the relative contribution of vegetation structure, composition and management for the provision of ecosystem services of air purification and climate regulation in urban green spaces, in particular the case of urban parks. This work was done in a large urban park with different types of vegetation surrounded by urban areas. As indicators of microclimatic effects and of air pollution levels we selected different metrics: lichen diversity and pollutants accumulation in lichens. Among lichen diversity, functional traits related to nutrient and water requirements were used as surrogates of the capacity of vegetation to filter air pollution and to regulate climate, and provide air purification and climate regulation ecosystem services, respectively. This was also obtained with very high spatial resolution which allows detailed spatial planning for optimization of ecosystem services. We found that vegetation type characterized by a more complex structure (trees, shrubs and herbaceous layers) and by the absence of management (pruning, irrigation and fertilization) had a higher capacity to provide the ecosystems services of air purification and climate regulation. By contrast, lawns, which have a less complex structure and are highly managed, were associated to a lower capacity to provide these services. Tree plantations showed an intermediate effect between the other two types of vegetation. Thus, vegetation structure, composition and management are important to optimize green spaces capacity to purify air and regulate climate. Taking this into account green spaces can be managed at high spatial resolutions to optimize these ecosystem services in urban areas and contribute to improve human well-beinginfo:eu-repo/semantics/publishedVersio

    3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense

    Get PDF
    Single Cause Single Cure Foundation. Fundação para a Ciência e Tecnologia (FCT) through the PhD grant (SFR/BD/146065/2019)NewG Lab Pharm

    S√≠ndrome da secre√ß√£o inapropriada do horm√īnio antidiur√©tico secund√°rio √† adenocarcinoma de pr√≥stata - relato de caso

    Get PDF
    Introdu√ß√£o: A s√≠ndrome da secre√ß√£o inapropriada do horm√īnio antidiur√©tico (SIADH) pode ser causada por tumores malignos ou benignos, doen√ßas neurol√≥gicas e medica√ß√Ķes. A hiponatremia √© o dist√ļrbio hidroeletrol√≠tico mais comum no paciente internado, e a SIADH uma das causas mais comuns. A hiponatremia est√° associada √† interna√ß√£o prolongada e aumento da morbidade e mortalidade dos pacientes. Portanto, seu tratamento correto √© essencial. O tumor maligno mais comum causador de SIADH √© o tumor de pulm√£o de pequenas c√©lulas; o c√Ęncer de pr√≥stata √© uma causa rara dessa s√≠ndrome. Relato de caso: Trata-se de paciente, do sexo masculino, de 75 anos, com diagn√≥stico de adenocarcinoma de pr√≥stata acinar usual, sem inicio de tratamento. Deu entrada no pronto socorro com quadro de rebaixamento do n√≠vel de consci√™ncia, sendo evidenciado hiponatremia grave em exame laboratorial. Ap√≥s descartadas outras causas, foi feito diagn√≥stico de SIADH paraneopl√°sica. Conclus√£o: A associa√ß√£o de SIADH e carcinoma de pr√≥stata √© pouco frequente e h√° poucas publica√ß√Ķes, por√©m √© uma condi√ß√£o de alta morbimortalidade. Um diagn√≥stico precoce, fornece possibilidade terap√™utica correta, diminuindo tempo de interna√ß√£o do paciente, morbidade e mortalidade
    corecore