A Qualitative Community Assessment of Racial/Ethnic Sexual Gender Minority Young Adults: Principles for Strategies to Motivate Action(s) for Realistic Tasks (SMART Thinking) Addressing HIV/AIDS, Viral Hepatitis, Mental Health, and Substance Abuse

HIV/STI, substance use, and mental health issues disproportionately affect racial/ethnic sexual minority young adults. These health vulnerabilities intensify across the life course, most notably when young adults are independent college students. To identify the perspectives of racial/ethnic sexual gender minorities living on or near an urban university, we implemented an intersectionality-informed SWOT (strengths, weakness, opportunities, and threats) analysis, as a qualitative community assessment situated within in a campus-community setting. The community needs assessment was the first step in the strategic prevention framework (SPF) to co-locate substance abuse, mental health, viral hepatitis, and HIV prevention care services for Latinx and Black/African American sexual gender minority young adults at a minority-serving institution. The SWOT analysis identified principles for selecting, adapting, and implementing an evidence-based intervention. The significance of these principles demonstrates the value of intersectionality in evidence-based interventions to influence health education and behavior among racial/ethnic sexual gender minorities

Subject characteristics in train and test set.

Subject characteristics in train and test set.</p

Example profile.

Solid line represents particle mass for a representative sample lipoprotein profile. Sizes: (VS = very small; S = small; M = Medium; L = Large). Regions: HDL = High Density Lipoprotein; MZ = Midzone; LDL = Low Density Lipoprotein; IDL = Intermediate Density Lipoprotein; VLDL = Very Low Density Lipoprotein.</p

Randomly selected profiles of test set subjects having low (< 2^nd percentile), median (49^th to 51^st percentiles) and high (> 98^th percentile) functional risk scores.

Randomly selected profiles of test set subjects having low (nd percentile), median (49th to 51st percentiles) and high (> 98th percentile) functional risk scores.</p

Cox model results of time to CVD event among test set subjects.

Cox model results of time to CVD event among test set subjects.</p

Simulated coefficient profiles under an alternative hypothesis for nested spline series with 8 and 15 degrees of freedom.

N = 500 (Panel A) and N = 5000 (Panel B). Thick (black) line is true profile. Thin (colored) lines are representative simulated profiles.</p

Simulation results.

Simulation results.</p

Simulated coefficient profiles under an alternative hypothesis for nested spline series with 7 and 13 degrees of freedom.

N = 500 (Panel A) and N = 5000 (Panel B). Thick (black) line is true profile. Thin (colored) lines are representative simulated profiles.</p

Estimated Cox regression coefficients across ion mobility profile.

Solid line represents estimated regression coefficients. Dashed lines represent upper and lower 95% confidence intervals for regression coefficients. Points indicate regions of significance (95% CI does not include zero). Sizes: (VS = very small; S = small; M = Medium; L = Large) Regions: HDL = High Density Lipoprotein; MZ = Midzone; LDL = Low Density Lipoprotein; IDL = Intermediate Density Lipoprotein; VLDL = Very Low Density Lipoprotein.</p

Hepatic distribution of a group of proteins in <i>Nrf2</i>+/+ and <i>Nrf2</i>-/- mice post-bile duct ligation (BDL) or sham operation (Sham).

Sections prepared from the livers of mice 40 days after BDL or sham operation were subjected to (A) NQO1, (B) CD133, (C) Fn14, and (D) DMBT1 immunostaining. Representative sections are shown.</p