11 research outputs found
Open Source Software Use in Indian Libraries: A Survey.
Get PDFThe term “Open Source” is a trending topic at present among LIS professionals in India. Open Source applications in libraries progressed as a matter of serious discussion among the library professionals. Stakeholders of Indian Library sector now a day’s realize the advantages of embracing Open Source softwares. This Paper attempts to find out the usage of Open Source software in Indian Libraries. It is found that there is a positive attitude from the part of library professionals towards the acceptance of Open Source softwares.The study also underscores the necessity of orientation Programmes for making Professionals more familiar for adoption of Open Source software in libraries
Open Source Software Use in Indian Libraries: A Survey.
Get PDFThe term “Open Source” is a trending topic at present among LIS professionals in India. Open Source applications in libraries progressed as a matter of serious discussion among the library professionals. Stakeholders of Indian Library sector now a day’s realize the advantages of embracing Open Source softwares. This Paper attempts to find out the usage of Open Source software in Indian Libraries. It is found that there is a positive attitude from the part of library professionals towards the acceptance of Open Source softwares.The study also underscores the necessity of orientation Programmes for making Professionals more familiar for adoption of Open Source software in libraries
Design, Synthesis, and Biological Evaluation of Nedd4 E3 Ubiquitin Ligase Small Molecule Inhibitors
No full text
The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment
Get PDFDecreased 5-HT2C receptor binding in the cerebral cortex and brain stem during pancreatic regeneration in rats
No full textA taxonomic review of the branchial fish parasitic genus Elthusa Schioedte & Meinert, 1884 (Crustacea: Isopoda: Cymothoidae) from Indian waters, with the description of three new species
No full textLuminescence Sensitization of Eu(III) Complexes with Aromatic Schiff Base and N,N’-Donor Heterocyclic Ligands: Synthesis, Luminescent Properties and Energy Transfer
No full textGrain alignment and its relationship with superconductivity and thermal transport of Ni-substituted Bi-2212 textured rods fabricated at two different growth rates
No full textIntestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD
No full textTissue hypoxia occurs when local oxygen demand exceeds oxygen supply. In chronic inflammatory conditions such as IBD, the increased oxygen demand by resident and gut-infiltrating immune cells coupled with vascular dysfunction brings about a marked reduction in mucosal oxygen concentrations. To counter the hypoxic challenge and ensure their survival, mucosal cells induce adaptive responses, including the activation of hypoxia-inducible factors (HIFs) and modulation of nuclear factor-kappa B (NF-kappa B). Both pathways are tightly regulated by oxygen-sensitive prolyl hydroxylases (PHDs), which therefore represent promising therapeutic targets for IBD. In this Review, we discuss the involvement of mucosal hypoxia and hypoxia-induced signalling in the pathogenesis of IBD and elaborate in detail on the role of HIFs, NF-kappa B and PHDs in different cell types during intestinal inflammation. We also provide an update on the development of PHD inhibitors and discuss their therapeutic potential in IBD
