The comparison of the SUV_max with every phase in the 4D and 3D PET scans for each patient.

<p>The comparison of the SUV_max with every phase in the 4D and 3D PET scans for each patient.</p

The projection of the tumor deformation vectors with the color scale superimposed on the CT scan for lung cancer patient 3 in the (A) transverse, (B) coronal and (C) sagittal views.

<p>(D) A rendering of the tumor deformation with a scout view of the thoracic CT for the same patient.</p

The characteristics of each tumor used in the analysis.

<p>The characteristics of each tumor used in the analysis.</p

The SUV_max percentage difference (PD%) between the 3D and 4D PET scans, comparing the tumor deformation (TD) with the location of tumors, including lung and esophageal cancer.

<p>The SUV_max percentage difference (PD%) between the 3D and 4D PET scans, comparing the tumor deformation (TD) with the location of tumors, including lung and esophageal cancer.</p

One example selected by the maximum PD is shown in the coronal view of the PET scan.

<p>(A) Differences observed between the tumor depiction in the 3D and 4D PET scans. The 4D contour was consistently lager in the SI direction. FDG-avid regions in the (B) T5% and (C) T55% respiratory phases moving outside the boundary depicted by the 3D contour.</p

A bar graph representing the SUV_max from 4D-PET and 4D-PET_ICT for each patient.

<p>The percentage difference between 4D-PET and 4D-PET_ICT is indicated on the top of each bar.</p

4D-CT and 4D-PET imaging.

<p>The respiratory cycle was divided into 10 phases based on motion amplitude. The 10 respiratory phases were labeled T5%, T15%, … T95%, with the T5% phase corresponding approximately to the normal end-inspiration and T55% to the end-expiration for both CT and PET. 4D-CT was used for attenuation correction of 4D-PET on a phase-by-phase basis so that they would match each other spatially.</p

Sagittal views of PET and CT fusion images across the ten phases of a complete respiration cycle.

<p>One example for 4D-PET/CT and 4D-PET _ICT/ICT are shown from patient 3.</p

The linear fit between the OFM calculated blood flow velocity values and corresponding MRA measured signal intensity values.

<p>(a) AP view, R = 0.71; (b) lateral view, R = 0.24.</p

Figure 2

<p>Coronal images of the (a) PET_FB/CT fusion image (left); PET_FB (right) and (b) PET_ab/CT_ab fusion image (left); and PET_ab (right) image for the selected patient, Patient 4. Misalignment around the tumor was observed in the PET_FB/CT fusion images (red arrow). (c) Vertical image profiles are drawn across the tumor in the PET_FB and PET_ab images.</p