Additional file 2: Figure S1. of The relation between the patient health questionnaire-15 and DSM somatic diagnoses

ROC curve: Using PHQ-15 for distinguishing patients in DSM-IV/DSM-5 diagnosis. (DOC 68 kb

Concurrent validity and convergent validity of the 5 segments of the C-DVT (Pearson’s r, n = 90).

Concurrent validity and convergent validity of the 5 segments of the C-DVT (Pearson’s r, n = 90).</p

The cumulative reliability (SEM% calculated on the basis of ICC) over trials.

<p>The SEM% of each dot is the cumulative reliability (calculated from the first trial to that trial).</p

Additional file 1: Table S1. of The relation between the patient health questionnaire-15 and DSM somatic diagnoses

Confirmatory factor analysis and goodness of fit statistics for the different models of PHQ-15. (DOC 32 kb

Standard error of measurement (SEM) and minimal detectable change (MDC) of the 5 segments and the C-DVT (n = 44).

<p>Standard error of measurement (SEM) and minimal detectable change (MDC) of the 5 segments and the C-DVT (n = 44).</p

Demographic characteristics and stroke-related information of the patients.

<p>Demographic characteristics and stroke-related information of the patients.</p

Table_1_High rate of invasive fungal infections during early cycles of azacitidine for patients with acute myeloid leukemia.docx

BackgroundAcute myeloid leukemia (AML) is a form of cancer that is characterized by infiltration of the bone marrow, blood, and other tissues by proliferative, clonal, abnormally differentiated, and occasionally poorly differentiated cells of the hematopoietic system. Patients with acute myeloid leukemia (AML) receiving azacitidine (AZA) alone or in combination with venetoclax (VEN-AZA) are at increased risk for invasive fungal infections (IFIs). We compared the incidence and risk of IFI during these treatment regimens in a single Taiwan hospital.Materials and methodsA total of 61 patients with AML received at least one course of AZA in the hematology ward of China Medical University Hospital (Taichung, Taiwan) between September 2012 and June 2020. Thirty-eight patients (62.3%) received AZA monotherapy; 23 (37.7%) received VEN-AZA.ResultsIncidence rates of probable and proven IFI were 18% and 1.6%, respectively, during AZA treatment. One proven case of Fusarium spp. infection was isolated by skin and soft tissue culture. Most (75%) IFI cases occurred during the first cycle of AZA therapy. Half of all IFI cases occurred in patients with prolonged neutropenia. The risk of IFI was significantly higher for the European LeukemiaNet (ELN) nonfavorable-risk group (intermediate- and adverse-risk group) versus the ELN favorable-risk group and for patients with prolonged neutropenia versus those without (PConclusionThe incidence of IFI was high in this AML cohort treated with AZA-containing regiments in Taiwan. The majority of IFI cases occurred during the early cycles of AZA (cycles 1–2). Prospective studies are needed to determine the optimal choice of antifungal prophylaxis agent during VEN-AZA therapy for AML. </p

Self-Assembly of Four Coordination Polymers in Three-Dimensional Entangled Architecture Showing Reversible Dynamic Solid-State Structural Transformation and Color-Changing Behavior upon Thermal Dehydration and Rehydration

A unique three-dimensional (3D) supramolecular compound, [Co­(dpe)­(BTC)­(H₂O)]­[Co­(dpe)­(BTC)­(H₂O)₃]­[Co­(dpe)­(HBTC)­(H₂O)]­[Co­(dpe)₂(H₂O)_3.5(EtOH)_0.5]·1.5H₂O (<b>1</b>; dpe = 1,2-bis­(4-pyridyl)­ethane and H₃BTC = benzenetricarboxylic acid), has been synthesized and structurally characterized by the single-crystal X-ray diffraction method. Compound <b>1</b> consists of four coordination polymers (CPs), two are two-dimensional (2D) layered metal–organic frameworks (MOFs) with (4,4) topology of [Co­(dpe)­(BTC)­(H₂O)]⁻ and [Co­(dpe)­(HBTC)­(H₂O)], whereas the other two are one-dimensional (1D) polymeric chains of [Co­(dpe)­(BTC)­(H₂O)₃]⁻ and [Co­(dpe)­(H₂O)_3.5(EtOH)_0.5]²⁺. The 3D supramolecular architecture of <b>1</b> is constructed via the penetration of interdigitated double-layered 2D rectangular-grid frameworks by two 1D coordination polymeric chains and entangled tightly by the subtle combination of intermolecular hydrogen bonding and π–π interactions among the four CPs. Controlled heating of the as-synthesized crystal <b>1</b> at ∼160 °C produces a desolvated <b>1</b> and accompanying color-changing behavior from pink to deep-blue, and the deep-blue desolvated <b>1</b> regenerates the pink rehydrated crystal with the chemical formula of [Co­(dpe)­(BTC)­(H₂O)]­[Co­(dpe)­(BTC)­(H₂O)₃]­[Co­(dpe)­(HBTC)­(H₂O)]­[Co­(dpe)₂(H₂O)₄]·3H₂O (<b>2</b>) upon exposure to water vapor. The structural determination of <b>2</b> shows almost the same structural characteristics as that of <b>1</b> with the only difference being the replacement of disordered coordinated solvent (half H₂O and half EtOH molecules) by H₂O and the numbers of solvated water molecules. The cyclic thermogravimetric analysis and powder X-ray diffraction measurements of desolvated <b>1</b> demonstrate a reversible rehydration/dehydration property, which is associated with solid-state structural transformation and thermally induced UV–vis absorption properties

Self-Assembly of Four Coordination Polymers in Three-Dimensional Entangled Architecture Showing Reversible Dynamic Solid-State Structural Transformation and Color-Changing Behavior upon Thermal Dehydration and Rehydration

A unique three-dimensional (3D) supramolecular compound, [Co­(dpe)­(BTC)­(H₂O)]­[Co­(dpe)­(BTC)­(H₂O)₃]­[Co­(dpe)­(HBTC)­(H₂O)]­[Co­(dpe)₂(H₂O)_3.5(EtOH)_0.5]·1.5H₂O (<b>1</b>; dpe = 1,2-bis­(4-pyridyl)­ethane and H₃BTC = benzenetricarboxylic acid), has been synthesized and structurally characterized by the single-crystal X-ray diffraction method. Compound <b>1</b> consists of four coordination polymers (CPs), two are two-dimensional (2D) layered metal–organic frameworks (MOFs) with (4,4) topology of [Co­(dpe)­(BTC)­(H₂O)]⁻ and [Co­(dpe)­(HBTC)­(H₂O)], whereas the other two are one-dimensional (1D) polymeric chains of [Co­(dpe)­(BTC)­(H₂O)₃]⁻ and [Co­(dpe)­(H₂O)_3.5(EtOH)_0.5]²⁺. The 3D supramolecular architecture of <b>1</b> is constructed via the penetration of interdigitated double-layered 2D rectangular-grid frameworks by two 1D coordination polymeric chains and entangled tightly by the subtle combination of intermolecular hydrogen bonding and π–π interactions among the four CPs. Controlled heating of the as-synthesized crystal <b>1</b> at ∼160 °C produces a desolvated <b>1</b> and accompanying color-changing behavior from pink to deep-blue, and the deep-blue desolvated <b>1</b> regenerates the pink rehydrated crystal with the chemical formula of [Co­(dpe)­(BTC)­(H₂O)]­[Co­(dpe)­(BTC)­(H₂O)₃]­[Co­(dpe)­(HBTC)­(H₂O)]­[Co­(dpe)₂(H₂O)₄]·3H₂O (<b>2</b>) upon exposure to water vapor. The structural determination of <b>2</b> shows almost the same structural characteristics as that of <b>1</b> with the only difference being the replacement of disordered coordinated solvent (half H₂O and half EtOH molecules) by H₂O and the numbers of solvated water molecules. The cyclic thermogravimetric analysis and powder X-ray diffraction measurements of desolvated <b>1</b> demonstrate a reversible rehydration/dehydration property, which is associated with solid-state structural transformation and thermally induced UV–vis absorption properties