Low density lipoprotein cholesterol control status among Canadians at risk for cardiovascular disease: findings from the Canadian Primary Care Sentinel Surveillance Network Database

Background To determine the prevalence of uncontrolled LDL-C in patients with high cardiovascular disease (CVD) risks across Canada and to examine its related factors. Methods Non-pregnant adults >20 years-old, who had a lipid test completed between January 1, 2009 and December 31, 2011 and were included in the Canadian Primary Care Surveillance Network (CPCSSN) database were studied. The Framingham-Risk-Score was calculated to determine the risk levels. A serum LDL-C level of >2.0 mmol/L was considered as being poorly controlled. Patients with a previous record of a cerebrovascular accident, peripheral artery disease, or an ischemic heart disease were regarded as those under secondary prevention. Logistic regression modeling was performed to examine the factors associated with the LDL-C control. Results A total of 6,405 high-risk patients were included in the study and, of this population, 68 % had a suboptimal LDL-C, which was significantly associated with the female gender (OR: 3.26; 95 % CI: 2.63–4.05, p < 0.0001) and no medication therapy (OR: 6.31, 95 % CI: 5.21–7.65, p < 0.0001). Those with comorbidities of diabetes, hypertension, obesity, and smokers had a better LDL-C control. Rural residents (OR: 0.64, 95 % CI: 0.52–0.78, p < 0.0001), and those under secondary prevention (OR: 0.42; 95 % CI: 0.35–0.51, p < 0.0001), were also more likely to have a better LDL-C control. Conclusion A high proportion of high-cardiac risk patients in Canadian primary care settings have suboptimal LDL-C control. A lack of medication therapy appears to be the major contributing factor to this situation

Introduction to the Douglass C. North Memorial Issue

This is the accepted version of the following article: Geoffrey M. Hodgson, ‘Introduction to the Douglass C. North memorial issue’, Journal of Institutional Economics, (early view) 1 December 2016, which has been published in final form at DOI: https://doi.org/10.1017/S1744137416000400 ©Cambridge UniversityPress 2016This introduction considers the highly influential contribution of Douglass C. North to economic history and institutional economics, as it developed from the 1960s until his death in 2015. It sketches the evolution of his arguments concerning the roles of institutions, organizations and human agency. North’s conception of the economic actor became progressively more sophisticated, by acknowledging the role of ideology and adopting insights from cognitive science. Eventually he abandoned the proposition that institutions are generally efficient, to propose instead that sub-optimal institutional forms could persist. A few noted criticisms of North’s work are also considered here, ranging from those which are arguably off the mark, to others that retain some force. The contributions to this memorial issue are outlined at the end of this introduction.Peer reviewe

Measurement of Cosmic-ray Electrons at TeV Energies by VERITAS

Cosmic-ray electrons and positrons (CREs) at GeV-TeV energies are a unique probe of our local Galactic neighborhood. CREs lose energy rapidly via synchrotron radiation and inverse-Compton scattering processes while propagating within the Galaxy and these losses limit their propagation distance. For electrons with TeV energies, the limit is on the order of a kiloparsec. Within that distance there are only a few known astrophysical objects capable of accelerating electrons to such high energies. It is also possible that the CREs are the products of the annihilation or decay of heavy dark matter (DM) particles. VERITAS, an array of imaging air Cherenkov telescopes in southern Arizona, USA, is primarily utilized for gamma-ray astronomy, but also simultaneously collects CREs during all observations. We describe our methods of identifying CREs in VERITAS data and present an energy spectrum, extending from 300 GeV to 5 TeV, obtained from approximately 300 hours of observations. A single power-law fit is ruled out in VERITAS data. We find that the spectrum of CREs is consistent with a broken power law, with a break energy at 710 $\pm$ 40$_{stat}$ $\pm$ 140$_{syst}$ GeV.Comment: 17 pages, 2 figures, accepted for publication in PR

Ask Me! Self-reported features of adolescents experiencing neglect or emotional maltreatment: a rapid systematic review

Neglect is often overlooked in adolescence, due in part to assumptions about autonomy and misinterpretation of behaviors being part of normal adolescent development. Emotional maltreatment (abuse or neglect) has a damaging effect throughout the lifespan, but is rarely recognized amongst adolescents. Our review aims to identify features that adolescents experiencing neglect and/ or emotional maltreatment report. METHOD: A rapid review methodology searched 8 databases (1990-2014), supplemented by hand searching journals, and references, identifying 2,568 abstracts. Two independent reviews were undertaken of 279 articles, by trained reviewers, using standardised critical appraisal. Eligible studies: primary studies of children aged 13-17 years, with substantiated neglect and/ or emotional maltreatment, containing self-reported features. RESULTS: 19 publications from 13 studies were included, demonstrating associations between both neglect and emotional maltreatment with internalising features (9 studies) including depression, post traumatic symptomatology and anxiety; emotional maltreatment was associated with suicidal ideation, while neglect was not (1 study); neglect was associated with alcohol related problems (3 studies), substance misuse (2 studies), delinquency for boys (1 study), teenage pregnancy (1 study), and general victimization for girls (1 study), while emotionally maltreated girls reported more externalising symptoms (1 study). Dating violence victimization was associated with neglect and emotional maltreatment (2 studies), while emotional abuse of boys, but not neglect, was associated with dating violence perpetration (1 study), and neither neglect nor emotional maltreatment had an association with low self-esteem (2 studies). Neither neglect nor emotional maltreatment had an effect on school performance (1 study), but neglected boys showed greater school engagement than neglected girls (1 study). CONCLUSIONS: If asked, neglected or emotionally maltreated adolescents describe significant difficulties with their mental health, social relationships, and alcohol or substance misuse. Practitioners working with youths who exhibit these features should recognize the detrimental impact of maltreatment at this developmental stage, and identify whether maltreatment is a contributory factor that should be addressed

The Design and Implementation of a Motor Controller

This thesis describes the design and implementation of a motor controller that is a customizable and cost effective replacement for the motor controllers used by Edwards Robotics Company (ERC). Extensive research of comparable products available in the market was conducted. The research formed the basis for the design specifications of the motor controller and a top-down design methodology was used to realize the controller. The controller was implemented and tested and meets all the design specifications. The most notable characteristics are a total cost of materials of approximately $101 and the capability of supplying a motor load with up to 40 amperes of DC current. Furthermore, the motor controller will serve as a viable solution for ERC’s needs

Energy Informatics and Business Model Generation

Sustainability needs to be tightly woven into the thinking of every senior executive if we are to develop a sustainable society. Furthermore, those companies seek to gain from meeting the needs of such a society need to forefront sustainability in all of their planning and product development. With this in mind, we have taken the business model generation canvas and developed a layer to stimulate Energy Informatics thinking. Business model generation is a technique to capture the essential features of an organization\u27s business. It addresses such issues as value proposition, sources of costs and revenues, partnerships, and customers in a concise and graphical manner. Osterwalder and Pigneur\u27s book has quickly become an international best seller because the technique is powerful and collectively engaging. We have taken the business model generation canvas and created a group collaborative version on Cacoo, which is web-based software for creating diagrams collaboratively. One of the features of Cacoo is the ability to create layers, so we have augmented our initial two-layer model of a blank canvas and key questions, with a layer containing questions to provoke Energy Informatics thinking and a layer containing examples of the application of Energy Informatics. Our goal is to use the workshop to discuss the content of each of these layers. Specifically, we would like participants to address the following questions: Do we have good questions for each segment of the canvas? Should there be several canvases for different audiences? What are some good Energy Informatics examples to stimulate thinking? The resulting canvas will be made publicly available to advance the development of Green IS