Planning for Secure Surface Bus Stops in Toronto

This paper evaluates the ways spatial planning understands and engages with personal security through a study of inner-suburban surface transit stops in Toronto, Ontario, Canada. Although often considered by planning, personal security does not appear to be subjected to the same level of attention as other design and planning priorities. The foundation for this study was a review of security focussed criminological, spatial planning, and a small quantity of legal texts in order to analyze overlaps and deviations. This was followed by analysis of relationship between personal security and the city’s public transit operator, the Toronto Transit Commission, through a review of historical texts and current policy documents guiding surface transit stop placement and design. The final component of this paper is a discussion of an audit of the design and placement of a selection of conventional bus stops in inner-suburban areas. Overall, there are indications that some progress is being made in addressing personal security but there is still significant room for improvement

Multipath Load Balancing Routing for Internet of Things

In the next-generation technology, Internet of Things (IoT), billions of smart objects will communicate with one another to make human lives more convenient. IoT is based on wireless sensor network (WSN), and Zigbee is one of the most popular WSN protocols. A mature IoT environment involves heavy WSN data transmission causing bottleneck problems. However, Zigbee’s AODV routing stack does not have load balance mechanism to handle bursty traffic. Therefore, we develop Multipath Load Balancing (MLB) Routing to substitute Zigbee’s AODV routing. Our proposed MLB consists of two main designs: LAYER_DESIGN and LOAD_BALANCE. LAYER_DESIGN assigns nodes into different layers based on node distance to IoT gateway. Nodes can have multiple next-hops delivering IoT data. All neighboring layer nodes exchange flow information containing current load, used by LOAD_BALANCE to estimate future load of next-hops. With MLB, nodes can choose the neighbors with the least load as the next-hops and thus can achieve load balance and avoid bottlenecks. Compared with Zigbee’s AODV and multipath version AODV (AOMDV), experiment results demonstrate that MLB achieves better load balance, lower packet loss rate, and better routing connectivity ratio in both grid and random uniform topologies. MLB provides a more convincing routing solution for IoT applications

Analysis of Mono-, Di- and Oligosaccharides by CE Using a Two-Stage Derivatization Method and LIF Detection.

A sensitive CE with LIF method has been developed for quantitative analysis of small carbohydrates. In this work, 17 carbohydrates including mono-, di- and oligosaccharides were simultaneously derivatized with 4-fluoro 7-nitrobenzo furazane (NBD-F) via a twostep reaction involving reductive amination with ammonia followed by condensation with NBD-F. Under the optimized derivatization conditions all carbo-hydrates were successfully derivatized within 2.5 h and separated within 15 min using borate buffer (90 mmol/L, pH 9.2). For sugar standards LODs were in the range of 49.7 to 243.6 nmol/L. Migration time and peak area reproducibility were better than RSD 0.1 and 3%, respectively. The method was applied to measure sugars in nanoliter volume samples of phloem sap obtained by stylectomy from wheat and to honeydew samples obtained from aphids feeding from wheat and willow

Hogel-Free Holography

Holography is a promising avenue for high-quality displays without requiring bulky, complex optical systems. While recent work has demonstrated accurate hologram generation of 2D scenes, high-quality holographic projections of 3D scenes has been out of reach until now. Existing multiplane 3D holography approaches fail to model wavefronts in the presence of partial occlusion while holographic stereogram methods have to make a fundamental tradeoff between spatial and angular resolution. In addition, existing 3D holographic display methods rely on heuristic encoding of complex amplitude into phase-only pixels which results in holograms with severe artifacts. Fundamental limitations of the input representation, wavefront modeling, and optimization methods prohibit artifact-free 3D holographic projections in today's displays. To lift these limitations, we introduce hogel-free holography which optimizes for true 3D holograms, supporting both depth- and view-dependent effects for the first time. Our approach overcomes the fundamental spatio-angular resolution tradeoff typical to stereogram approaches. Moreover, it avoids heuristic encoding schemes to achieve high image fidelity over a 3D volume. We validate that the proposed method achieves 10Â dB PSNR improvement on simulated holographic reconstructions. We also validate our approach on an experimental prototype with accurate parallax and depth focus effects

End of performance prediction of lithium-ion batteries

Rechargeable batteries are critical components for the performance of portable electronics and electric vehicles. The long-term health performance of rechargeable batteries is characterized by state of health, which can be quantified by end of performance (EOP) and remaining useful performance. Focusing on EOP prediction, this article first proposes an accelerated testing version of the trend-renewal process model to address this decision problem. The proposed model is also applied to a real case study. Finally, a NASA dataset is used to address the prediction performance of the proposed model. Comparing with the existing prediction methods and time series models, our proposed procedure has better performance in the EOP prediction.acceptedVersionPublisher embargo applies until January 18, 202

Spectrum and Clinical Course of Visual Field Abnormalities in Ethambutol Toxicity

Visual toxicities from ethambutol are rare but represent one of the few causes of non-glaucomatous and non-compressive bitemporal hemianopsia. The authors present a six-patient case series illustrating variable clinical presentation and reversibility of visual loss in patients treated with ethambutol for Mycobacterium avium complex, including four patients who presented with visual field defects suggestive of bitemporal hemianopsia. Two additional patients were being followed for glaucoma, developed visual field defects with ethambutol treatment, and subsequently recovered with cessation of drug. In patients being treated with ethambutol, reversible bitemporal hemianopsia was the most commonly noted presentation of ethambutol toxicity

Precision in treatment evaluation: importance of minimal clinically important differences (MCIDs) of outcome measures for autoimmune blistering diseases

Autoimmune blistering diseases (AIBDs) comprise a group of rare conditions marked by autoantibodies that specifically target intercellular adhesion molecules. Despite the progress made in comprehending the disease and the increasing number of treatment options available, there is still no definitive cure for AIBDs such as pemphigus, and it continues to have a devastating impact on those affected. The challenges in achieving new approved therapies for AIBDs are complex and multifaceted. One significant obstacle was the prior lack of validated and standardized outcome measures, which are crucial for ensuring precise comparisons between new and traditional therapies. This gap in knowledge has prompted the development of minimal clinically important differences (MCIDs), which enable efficient and reliable comparison of therapeutic outcomes between trials. MCID is defined as the minimum difference in an outcome measure that indicates a clinically significant improvement/deterioration in disease severity. Additionally, MCIDs provide a patient-centered approach to evaluating treatment efficacy, by considering whether patients experience a subjective improvement in their symptoms. Therefore, this literature review will examine the derivation and significance of MCIDs for various scoring systems in AIBDs