CS 156: Introduction to Artificial Intelligence Course Redesign

Poster summarizing course redesign activities for CS 156: Introduction to Artificial Intelligence.https://scholarworks.sjsu.edu/davinci_itcr2014/1016/thumbnail.jp

CS 156: Introduction toArtificial Intelligence Textbook Alternatives

Poster summarizing cost saving textbook alternatives for CS 156: Introduction to Artificial Intelligence.https://scholarworks.sjsu.edu/davinci_tap2014/1009/thumbnail.jp

CS 160: Software Engineering Textbook Alternatives

Poster summarizing cost saving textbook alternatives fo rCS 160: Software Engineering.https://scholarworks.sjsu.edu/davinci_tap2014/1010/thumbnail.jp

Diagnosis and Conservative Treatment of Skeletal Class III Malocclusion with Anterior Crossbite and Asymmetric Maxillary Crowding

A 28-year-9-month male presented for orthodontic consultation for skeletal Class III malocclusion (ANB -30) with a modest asymmetric Class II/III molar relationship, complicated by an anterior crossbite, deep bite, and 12mm of asymmetric maxillary crowding. Despite the severity of a malocclusion, Discrepancy Index (DI) = 37, the patient desired non-invasive camouflage treatment. Lin’s 3-Ring diagnosis revealed that treatment without extractions or orthognathic surgery was a viable approach. Arch length analysis indicated that differential interproximal enamel reduction (IPR) could resolve the crowding and midline discrepancy, but a miniscrew in the infrazygomatic crest (IZC) was needed to retract the right buccal segment. The patient accepted the complex, staged treatment plan with the understanding that it would require ~3.5 years. Fixed appliance treatment with passive self ligating (PSL) brackets, early light short elastics (ELSE), bite turbos (BTs), IPR, and IZC retraction opened the vertical dimension of occlusion (VDO), improved the ANB 20 and achieved an excellent alignment, as evidenced by a CRE of 26 and a Pink and White (P&W) dental esthetic score of 3. The worksheets for the DI, CRE, and P&W scores are attached within this case report

Comparative Maps of Safety Features for Fission and Fusion Reactors

Abstract The differences between nuclear fission and fusion have been discussed widely in the literature. However, little has been done to investigate the key differences in safety designs and regulatory requirements between the nuclear reactor types. In this study, an innovative methodology was successfully developed to map nuclear safety features to the fundamental safety principles set out by the nuclear regulators. Three safety cases were assessed in the mapping study, a research fusion reactor (Joint European Torus), a research fission reactor (Tsing Hua Open-pool Reactor) and a commercial fission reactor (Hinkley Point C). The graphical representation allowed a comparative analysis of the safety features and fundamental principles which revealed differences between the hazard profiles of fission and fusion reactors and provided important insights for the creation of a similar map for a future commercial fusion device.</jats:p

A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging

An ongoing challenge in biomedical research is the search for simple, yet robust assays using 3D cell cultures for toxicity screening. This study addresses that challenge with a novel spheroid assay, wherein spheroids, formed by magnetic 3D bioprinting, contract immediately as cells rearrange and compact the spheroid in relation to viability and cytoskeletal organization. Thus, spheroid size can be used as a simple metric for toxicity. The goal of this study was to validate spheroid contraction as a cytotoxic endpoint using 3T3 fibroblasts in response to 5 toxic compounds (all-trans retinoic acid, dexamethasone, doxorubicin, 5′-fluorouracil, forskolin), sodium dodecyl sulfate (+control), and penicillin-G (−control). Real-time imaging was performed with a mobile device to increase throughput and efficiency. All compounds but penicillin-G significantly slowed contraction in a dose-dependent manner (Z’ = 0.88). Cells in 3D were more resistant to toxicity than cells in 2D, whose toxicity was measured by the MTT assay. Fluorescent staining and gene expression profiling of spheroids confirmed these findings. The results of this study validate spheroid contraction within this assay as an easy, biologically relevant endpoint for high-throughput compound screening in representative 3D environments

Combined heat and power and campus carbon footprint reduction

Gemstone Team Cogeneration TechnologyCombined heat and power (CHP), the sequential generation of electrical and thermal energy in an integrated process, has emerged as an economically viable and immediately effective power generation method to reduce greenhouse gas emissions. CHP systems utilize both the electricity and waste heat created during energy production to increase fuel efficiency and decrease carbon emissions compared to conventional heat and power generation systems. This research examines the extent to which universities can decrease carbon emissions by identifying strategies for installation and operation of highly efficient, gas-fired CHP. To best identify how to enhance campus CHP, existing university plants were surveyed to benchmark how efficiently universities operate CHP. Strategies for increasing turbine efficiency were then considered. Demand for efficient CHP on university campuses was identified and connected to specific turbine characteristics. Policy frameworks to support the development of efficient CHP implementation and operation were examined and challenges identified. This report provides recommendations for overcoming technical, economic, and policy challenges to attain immediate emissions reductions through university usage of CHP

ADC, D, f dataset calculated through the simplified IVIM model, with MGMT promoter methylation, age, and ECOG, in 38 patients with wildtype IDH glioblastoma

Patients undergoing standard chemoradiation post-resection had MRIs at radiation planning and fractions 10 and 20 of chemoradiation. MRIs were 1.5T and 3D T2-FLAIR, pre- and post-contrast 3D T1-weighted (T1) and echo planar DWI with three b-values (0, 500, and 1000s/mm2) were acquired. T2-FLAIR was coregistered to T1C images. Non-overlapping T1 contrast-enhancing (T1C) and nonenhancing T2-FLAIR hyperintense regions were segmented, with necrotic/cystic regions, the surgical cavity, and large vessels excluded. The simplified IVIM model was used to calculate voxelwise diffusion coefficient (D) and perfusion fraction (f) maps; ADC was calculated using the natural logarithm of b&nbsp;=&nbsp;1000 over b&nbsp;=&nbsp;0 images. T1C and T2-FLAIR segmentations were brought into this space, and medians calculated. MGMT promoter methylation status (MGMTPMS), age at diagnosis, and Eastern Cooperative Oncology Group (ECOG) performance status were extracted from electronic medical records. The data were presented, analyzed, and described in the article, "Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype Glioblastoma", published in Radiotherapy and Oncology [1]

Increased Mortality Associated with Well-Water Arsenic Exposure in Inner Mongolia, China

We conducted a retrospective mortality study in an Inner Mongolian village exposed to well water contaminated by arsenic since the 1980s. Deaths occurring between January 1, 1997 and December 1, 2004 were classified according to underlying cause and water samples from household wells were tested for total arsenic. Heart disease mortality was associated with arsenic exposure, and the association strengthened with time exposed to the water source. Cancer mortality and all-cause mortality were associated with well-water arsenic exposure among those exposed 10–20 years. This is the first study to document increased arsenic-associated mortality in the Bayingnormen region of Inner Mongolia