Ketene Is a Dienophile for [4 + 2] (Diels−Alder) Reactions across Its CO Bond¹

Ketene Is a Dienophile for [4 + 2] (Diels−Alder) Reactions across Its CO Bond1</sup

Solid-State Thiotropolone: An Extremely Rapid Intramolecular Proton Transfer

Through variable-temperature solution-state NMR and molten- and solid-state CP/MAS 13C NMR spectra, thiotropolone is found to exist as two rapidly equilibrated tautomeric structures, thione and enethiol, even in the solid state far below the melting point. The crystal structure shows an almost perpendicular packing, suggesting that the intramolecular hydrogen bond is dominant

Solid-State Thiotropolone: An Extremely Rapid Intramolecular Proton Transfer

Through variable-temperature solution-state NMR and molten- and solid-state CP/MAS 13C NMR spectra, thiotropolone is found to exist as two rapidly equilibrated tautomeric structures, thione and enethiol, even in the solid state far below the melting point. The crystal structure shows an almost perpendicular packing, suggesting that the intramolecular hydrogen bond is dominant

Solid-State Thiotropolone: An Extremely Rapid Intramolecular Proton Transfer

Through variable-temperature solution-state NMR and molten- and solid-state CP/MAS 13C NMR spectra, thiotropolone is found to exist as two rapidly equilibrated tautomeric structures, thione and enethiol, even in the solid state far below the melting point. The crystal structure shows an almost perpendicular packing, suggesting that the intramolecular hydrogen bond is dominant

Ketene Is a Dienophile for [4 + 2] (Diels−Alder) Reactions across Its CO Bond¹

Ketene Is a Dienophile for [4 + 2] (Diels−Alder) Reactions across Its CO Bond1</sup

The expression of melanocytic markers in undifferentiated and differentiated ADSCs detected by immunofluorescence microscopy.

The expression levels of HMB45, MITF, MelEM, Mel2, MelanA, MATP, and tyrosinase (TYR) in undifferentiated and differentiated ADSCs, as well as NHEMs, were examined by immunofluorescence microscopy. All melanocytic markers except for TYR were detected.</p

Solid-State Thiotropolone: An Extremely Rapid Intramolecular Proton Transfer

Through variable-temperature solution-state NMR and molten- and solid-state CP/MAS 13C NMR spectra, thiotropolone is found to exist as two rapidly equilibrated tautomeric structures, thione and enethiol, even in the solid state far below the melting point. The crystal structure shows an almost perpendicular packing, suggesting that the intramolecular hydrogen bond is dominant

The expression of melanocytic markers in undifferentiated and differentiated ADSCs detected by RT-PCR.

The expression levels of HMB45, MITF, PAX3, and KIT in undifferentiated ADSCs and differentiated ADSCs were compared with those in melanocytes by RT-PCR. The expression levels of HMB45, MITF, PAX3, and KIT were higher in differentiated ADSCs than in undifferentiated ADSCs.</p

siRNA-mediated downregulation of HMB45 in differentiated ADSCs.

siRNA resulted in the downregulation of HMB45 in undifferentiated ADSCs and differentiated ADSCs.</p

The expression of HMB45 and MITF in Mel2-positive and Mel2-negative cells.

The expression of HMB45 and MITF in Mel2-positive cells was increased compared to that in Mel2-negative cells, as shown by immunofluorescence microscopy (A). The expression of HMB45 and MITF in Mel2-positive cells was increased compared to that in Mel2-negative cells, as shown by RT-PCR (B). There was almost no difference in the expression of KIT in Mel2-positive cells and Mel2-negative cells, as shown by RT-PCR (B). The expression of MITF in Mel2-positive cells was increased compared to that in Mel2-negative cells, as shown by western blot analysis (C).</p