Rational Co-Doping of SrZrO₃ and BaTiO₃ in Bi_0.5Na_0.5TiO₃ for Extraordinary Energy Storage and Electrocaloric Performances

The modification of the microstructure and electrical behaviors, through rational designing the composition of co-dopants (SrZrO3 and BaTiO3) in a modified Bi0.5Na0.5TiO3-based ternary system, has been systematically investigated. The extraordinary and controllable energy storage (maximum Wrec ∼ 1.15 J/cm3 and Wrec/ΔE × 100% ∼ 1.92% J/(kV cm2)) and electrocaloric (the maximum |ΔT| ∼ 2.13 K and the electrocaloric coefficient |ΔT|/ΔE ∼ 0.36 × 10–6 K m/V) performances can be integrated into this system, which are higher than those of other Bi0.5Na0.5TiO3-based systems reported previously. Meanwhile, this ternary system shows good thermal stability over a wide temperature range from room temperature to 120 °C. It is found that the coexistence and competition of linearly dielectric SrZrO3 and ferroelectric BaTiO3 deliver the doping evolution of polar nanoregions and obviously reduce the remnant polarization as well as the coercive field, resulting in enhanced energy storage and electrocaloric responses. These findings make Bi0.5Na0.5TiO3-BaTiO3-SrZrO3 (BNT-BT-SZ) ceramics very promising candidates as multifunctional materials

Additional file 3 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 3: Figure S3. BMNC count in each group. Cells were isolated on Day 10 (n = 6 for Control group, n = 3 for Model group, n = 8 for SMI group, n = 6 for S+Rg group, n = 6 for S group and n = 7 for Rg group). The results are expressed as the means ± SEM. ##p < 0.01, compared with Control group; ＊p < 0.05, ＊＊p < 0.01, compared with Model group; ns, no significant difference compared with Model group

Additional file 2 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 2: Figure S2. HPLC analysis of carbohydrates in SMI (Lot No. 1907018)

Additional file 1 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 1: Figure S1. HPLC analysis of SMI from different batches. (A) HPLC analysis of SMI (Lot No. 1907018). (B) HPLC analysis of SMI (Lot No. 1907229). (C) HPLC analysis of SMI (Lot No. 1907277)

Additional file 5 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 5: Table S2. DEGs in Model, S+Rg, S, and Rg groups

Pressure-Induced Bifurcation in the Photoluminescence of Red Carbon Quantum Dots: Coexistence of Emissions from Surface Groups and Nitrogen-Doped Cores

Carbon quantum dots (CDs) with favorable fluorescent properties have stimulated considerable effort to modulate their photoluminescence (PL) for bioimaging and sensing. However, the fluorescent mechanisms are still only partially understood due to the diverse physicochemical properties of CDs prepared by various synthesis methods and postpreparation processes. In this report, pressure-induced bifurcation of PL is reported in red carbon quantum dots (R-CDs) for the first time. The splitting of PL into an irreversible blue-shifted peak and a reversible red-shifted peak under pressure suggests the coexistence of multiple fluorescent mechanisms in R-CDs, i.e., emissions from surface groups and nitrogen-doped cores. The concentration and excitation laser energy dependencies of pressure-induced bifurcation, as well as the time-resolved PL, further support the coexistence of multiple emitters. Our results provide a method for distinguishing between the different fluorescent mechanisms related to surface groups and carbon cores in CDs

Additional file 10 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 10: Table S7. GO analysis of DEGs uniquely regulated in the S+Rg group

Inhibition of MMP2 decreases apoptosis and attenuates insulin secretion dysfunction caused by oxidative stress in INS-1 cells.

<p>INS-1 cells were treated with GA (200 mg/L) or BSA (200 mg/L) for 24 h. MMP2 inhibitor (OA-Hy) was dissolved in DMSO and used at a final concentration of 20 µmol/L with GA for 24 h. (a, b) The gelatinolytic activity of MMP2 in different groups. (c) Apoptotic cells in different groups. Annexin V positive cells (including Annexin V single positive population and the Annexin V and PI double positive population) representing apoptotic cells were mainly located in the right upper quadrant and right lower quadrant. (d) Average apoptotic rate in the three groups. (e) Insulin secretion of INS-1 cells stimulated with 3.3 mmol/L glucose or 16.7 mmol/L glucose in the different groups. *<i>P<0.05 vs</i> the corresponding control group; ^#<i>P<0.05 vs</i> corresponding GA-treated group (f) Insulin release index (IRI) of each group. Data are shown as means ± SD, <i>P<0.05</i> indicates a statistically significant difference. *<i>P<0.05 vs</i> the control group; ^#<i>P<0.05 vs</i> GA-treated group.</p

Additional file 9 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 9: Table S6. GO analysis of common DEGs in S and S+Rg groups

Additional file 11 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

Additional file 11: Table S8. KEGG pathway analysis of Model, S+Rg, S, and Rg groups