Synthesis, crystal structure, and properties of a tetrairon cluster based on 2-methyl-8-hydroxyquinoline

<p>The synthesis, structure, and magnetic properties of a tetrairon(III) complex [Fe₄(<i>μ</i>₂-O)₂Cl₄(L)₄]·0.5H₂O (<b>1</b>, L = 2-methyl-8-hydroxyquinoline), which was prepared under solvothermal conditions and characterized by IR spectra, elemental analysis, TG, and single-crystal X-ray crystal diffraction, are presented. Each Fe center adopts a distorted trigonal bipyramid geometry and is coordinated with three oxygen atoms, one nitrogen atom, and one chlorine atom. Each 2-methyl-8-hydroxyquinoline is coordinated to two Fe^III ions with <i>μ</i>₂-<i>η</i>²:<i>η</i>¹ coordination mode. The magnetic properties of the complex are dominated by antiferromagnetic exchange interactions.</p

HS worsen and CCL20 antibody improves lung damage in IgAN mice.

<p>Representative images of HE stained lungs from mice as indicated (200×).</p

HS increases and CCL20 antibody decreases Th17-related cytokines in IgAN mice.

<p>(A): Renal CCL20 concentrations of each groups; (B): Renal IL-17A concentrations of each groups; (C): Renal IL-21 concentrations of each groups; (D): Renal IL-6 concentrations of each groups. ^#<i>vs</i> control group, <i>P</i><0.05; ^*<i>vs</i> IgAN group, ^&<i>vs</i> HS-IgAN group <i>P</i><0.05.</p

HS worsens and CCL20 antibody improves renal damage in IgAN mice.

<p>Representative images of HE-stained (A, 400×), PAS-stained (B, 400×), Immunofluorescence (C, 200×) and transmission electron micrographs (D) kidney sections from mice as indicated. For immunofluorescence staining, IgA antibody was used. The arrows in D point to high electron dense deposition in glomerular mesangial region.</p

HS increases and CCL20 antibody decreases ACR in IgAN mice.

<p>^#<i>vs</i> control group, <i>P</i><0.05; ^*<i>vs</i> IgAN group, <i>P</i><0.05; ^&<i>vs</i> HS-IgAN group, <i>P</i><0.05.</p

HS increases and CCL20 antibody decreases abnormal glomeruli in IgAN mice.

<p>PAS-stained kidney sections were evaluated for the presence of abnormal glomeruli. ^#<i>vs</i> control group, <i>P</i><0.05; * <i>vs</i> IgAN group, <i>P</i><0.05; ^&<i>vs</i> HS-IgAN group, <i>P</i><0.05.</p

HS increases and CCL20 antibody decreases Th17/Treg in IgAN mice.

<p>Isolated leukocytes were analyzed by flow cytometry. For production of IL-17 and Foxp3, numbers are counts in percentage of CD4⁺T cells. Collective analysis of the results from each group (C, D, E). ^#<i>vs</i> control group, <i>P</i><0.05; ^*<i>vs</i> IgAN group, <i>P</i><0.05; ^&<i>vs</i> HS-IgAN group, <i>P</i><0.05.</p

One-Dimensional Integrated MnS@Carbon Nanoreactors Hybrid: An Alternative Anode for Full-Cell Li-Ion and Na-Ion Batteries

Manganese sulfide (MnS) has triggered great interest as an anode material for rechargeable Li-ion/Na-ion batteries (LIBs/SIBs) because of its low cost, high electrochemical activity, and theoretical capacity. Nevertheless, the practical application is greatly hindered by its rapid capacity decay lead by inevitable active dissolutions and volume expansions in charge/discharge cycles. To resolve the above issues in LIBs/SIBs, we herein put forward the smart construction of MnS nanowires embedded in carbon nanoreactors (MnS@C NWs) via a facile solution method followed by a scalable in situ sulfuration treatment. This engineering protocol toward electrode architectures/configurations endows integrated MnS@C NWs anodes with large specific capacity (with a maximum value of 847 mA h g^–1 in LIBs and 720 mA h g^–1 in SIBs), good operation stability, excellent rate capabilities, and prolonged cyclic life span. To prove their potential real applications, we have established the full cells (for LIBs, MnS@C//LiFePO₄; for SIBs, MnS@C//Na₃V₂(PO₄)₃), both of which are capable of showing remarkable specific capacities, outstanding rate performance, and superb cyclic endurance. This work offers a scalable, simple, and efficient evolution method to produce the integrated hybrid of MnS@C NWs, providing useful inspiration/guidelines for anodic applications of metal sulfides in next-generation power sources

Overlapped Sequence Types (STs) and Serogroups of Avian Pathogenic (APEC) and Human Extra-Intestinal Pathogenic (ExPEC) <i>Escherichia coli</i> Isolated in Brazil

<div><p>Avian pathogenic <i>Escherichia coli</i> (APEC) strains belong to a category that is associated with colibacillosis, a serious illness in the poultry industry worldwide. Additionally, some APEC groups have recently been described as potential zoonotic agents. In this work, we compared APEC strains with extraintestinal pathogenic <i>E. coli</i> (ExPEC) strains isolated from clinical cases of humans with extra-intestinal diseases such as urinary tract infections (UTI) and bacteremia. PCR results showed that genes usually found in the ColV plasmid (<i>tsh</i>, <i>iuc</i>A, <i>iss</i>, and <i>hly</i>F) were associated with APEC strains while <i>fyu</i>A, <i>irp</i>-2, <i>fep</i>C <i>sit</i>D_chrom, <i>fim</i>H, <i>crl</i>, <i>csg</i>A, <i>afa</i>, <i>iha</i>, <i>sat</i>, <i>hly</i>A, <i>hra</i>, <i>cnf</i>1, <i>kps</i>MTII, <i>clpV</i>_Sakai and <i>mal</i>X were associated with human ExPEC. Both categories shared nine serogroups (O2, O6, O7, O8, O11, O19, O25, O73 and O153) and seven sequence types (ST10, ST88, ST93, ST117, ST131, ST155, ST359, ST648 and ST1011). Interestingly, ST95, which is associated with the zoonotic potential of APEC and is spread in avian <i>E. coli</i> of North America and Europe, was not detected among 76 APEC strains. When the strains were clustered based on the presence of virulence genes, most ExPEC strains (71.7%) were contained in one cluster while most APEC strains (63.2%) segregated to another. In general, the strains showed distinct genetic and fingerprint patterns, but avian and human strains of ST359, or ST23 clonal complex (CC), presented more than 70% of similarity by PFGE. The results demonstrate that some “zoonotic-related” STs (ST117, ST131, ST10CC, ST23CC) are present in Brazil. Also, the presence of moderate fingerprint similarities between ST359 <i>E. coli</i> of avian and human origin indicates that strains of this ST are candidates for having zoonotic potential.</p></div

Frequencies of sequence types (STs) among APEC (n = 76) and ExPEC (n = 53) strains isolated in Brazil.

<p>Frequencies of sequence types (STs) among APEC (n = 76) and ExPEC (n = 53) strains isolated in Brazil.</p