Integrating Nursing Context And Technology Usage For English Speaking Empowerment

English for specific purposes (ESP) must be taught to meet particular needs of non-English language students (Hutchinson & Waters, 1987, p.21). It gives direct suggestion that learning process should be designed in such away not only to meet the learning objectives of the students but also to give the students meaningful and enjoyable learning experiences (Crawford, 2013, p.1 81). The condition becomes more challenging when the ESP teachers are only having English language background. It implies that learning context, which meets the students’ needs, should be carried out in learning process along with the suitable and enjoyable learning strategies where the students can feel the pleasure instead of pressure. By considering the three steps of ESP course designing suggested by Nitu (2002, p.154), this paper aims at proving the effectiveness of integrating the students’ learning contexts and the students’ pleasure to empower the students’ speaking performance in Health Science Faculty of Musi Charitas Catholic University Palembang. This study belongs to experimental research with pre- and post-design. By the end of the study, it was proven that integrating the nursing field context and the usage of technology in the classroom can help the students improve their English speaking skills. For evidential information, some videos of learning process are presente

Table_2_Roles of gut microbiota in androgenetic alopecia: insights from Mendelian randomization analysis.DOCX

BackgroundAndrogenetic alopecia (AGA) is the most common type of androgen-associated hair loss. Previous studies have indicated an association between the gut microbiota and AGA. To delve deeper, we executed a two-sample Mendelian randomization (MR) analysis to investigate the potential causal relationship between the gut microbiota and AGA.MethodsA two-sample MR investigation was utilized to delve into the intricate interplay between gut microbiota and AGA. Information regarding 211 gut microbial taxa was sourced from the MiBioGen consortium. The summary statistics of the genome-wide association studies (GWAS) for AGA were obtained from the FinnGen biobank, which included 195 cases and 201,019 controls. Various analytical approaches, including Inverse Variance Weighting (IVW), Weighted Median, MR-Egger, Weighted Mode, and Simple Mode were employed to evaluate the causal impact of gut microbiota on AGA. Sensitivity analyses were subsequently conducted to affirm the robustness of the findings.ResultsA two-sample MR investigation unveiled the genus Olsenella, genus Ruminococcaceae UCG-004, and genus Ruminococcaceae UCG-010 were identified as risk factors associated with AGA. In contrast, the family Acidaminococcaceae and genus Anaerofilum, along with the genus Ruminiclostridium 9, demonstrated a protective effect. The sensitivity analyses provided additional assurance that the findings of the current study were less susceptible to the influence of confounding variables and biases.ConclusionThe MR study has established a link between specific gut microbiota and AGA, offering evidence for the identification of more precisely targeted probiotics. This discovery has the potential to aid in the prevention, control, and reversal of AGA progression.</p

Table_1_Roles of gut microbiota in androgenetic alopecia: insights from Mendelian randomization analysis.XLSX

BackgroundAndrogenetic alopecia (AGA) is the most common type of androgen-associated hair loss. Previous studies have indicated an association between the gut microbiota and AGA. To delve deeper, we executed a two-sample Mendelian randomization (MR) analysis to investigate the potential causal relationship between the gut microbiota and AGA.MethodsA two-sample MR investigation was utilized to delve into the intricate interplay between gut microbiota and AGA. Information regarding 211 gut microbial taxa was sourced from the MiBioGen consortium. The summary statistics of the genome-wide association studies (GWAS) for AGA were obtained from the FinnGen biobank, which included 195 cases and 201,019 controls. Various analytical approaches, including Inverse Variance Weighting (IVW), Weighted Median, MR-Egger, Weighted Mode, and Simple Mode were employed to evaluate the causal impact of gut microbiota on AGA. Sensitivity analyses were subsequently conducted to affirm the robustness of the findings.ResultsA two-sample MR investigation unveiled the genus Olsenella, genus Ruminococcaceae UCG-004, and genus Ruminococcaceae UCG-010 were identified as risk factors associated with AGA. In contrast, the family Acidaminococcaceae and genus Anaerofilum, along with the genus Ruminiclostridium 9, demonstrated a protective effect. The sensitivity analyses provided additional assurance that the findings of the current study were less susceptible to the influence of confounding variables and biases.ConclusionThe MR study has established a link between specific gut microbiota and AGA, offering evidence for the identification of more precisely targeted probiotics. This discovery has the potential to aid in the prevention, control, and reversal of AGA progression.</p

Additional file 2: Figure S1. of Circular RNA expression profiles and features in human tissues: a study using RNA-seq data

The top 10 circRNAs expression of each sample in six human adult normal tissues. (JPEG 161 kb