Examining the effects of lead on the life of larval zebrafish (1-7 days old)

Lead (Pb) is a toxic metal and and can cause variety of disorders and effect on neu-ronal function and neurodevelopment. Using zebrafish as a model, the aim of this study was to evaluate the effects of concentrations of Pb2+ on the life of zebrafish larvae (from 1 to 7 days old)yesBelgorod State Universit

DESIGNING A MODEL TO ENSURE QUALITY MANAGEMENT OF SCIENCE AND TECHNOLOGY FOR AUTONOMOUS INSTITUTIONS IN VIETNAM BASED ON THE IMPACT OF QUALITY ASSURANCE IN EDUCATION

Alongside internal quality assurance measures, external quality assessment serves as a mechanism to ensure the quality of education in Vietnam, proven to offer various opportunities (enrollment, research collaboration, technology transfer, etc.) as relevant parties become aware of and trust in the educational institution's quality. Consequently, the impact of educational quality assessment prompts systematic quality assurance activities within the university, yielding high results based on post-assessment expert recommendations. However, among the university activities in Vietnam, scientific and technological management has been identified as one of the few standards with a relatively low average score [1], [2]. Proposing a suitable research model to assess the influence of educational quality assessment on the scientific and technological management of autonomous universities in Vietnam will assist these institutions in identifying crucial elements of scientific and technological management. This will facilitate the implementation of more feasible activities to ensure the quality of these operations, contributing significantly to the overall educational quality of the institution

Preservation and Promotion of Traditional Culture of Ethnic Minorities in Tourism Development in Tuyen Quang Province, Vietnam

 Preserving and promoting the traditional cultural values of ethnic minority communities will contribute to enriching their cultural heritage, strengthening unity and solidarity among ethnic groups, and creating a significant internal driving force for sustainable national development. Currently, ethnic minorities in Tuyen Quang Province still maintain their unique customs, traditions, and cultural practices. These are potential strengths and favorable conditions that contribute to the sustainable tourism development of Tuyen Quang Province, creating an appealing attraction for visitors to explore, discover, and experience the cultural tourism of Tuyen Quang

Preserve and Promote the Traditional Cultural Values of the Tay and Nung people in Tourism Development in Cao Bang Province, Vietnam

The development of tourism linked to the unique cultural values of each ethnic community is becoming an essential trend in the tourism sector. The Tay and Nung ethnic communities in Cao Bang province are among the ethnic minority groups in Vietnam, with rich cultural and social lives that hold significant importance in tourism development. The traditional cultural values of the Tay and Nung people deeply embody the cultural identity of the ethnic group and represent a rich cultural potential in the tourism development of Cao Bang province. Successfully managing the relationship between preserving and promoting the traditional cultural values of the Tay and Nung people in Cao Bang province in connection with sustainable tourism development will contribute to changing livelihoods, enhancing the quality of life for the people, and ensuring the sustainable development of the country

Clinical Outcomes of Patients With Drug-Resistant Tuberculous Meningitis Treated With an Intensified Antituberculosis Regimen.

Drug-resistant tuberculous meningitis (TBM) is difficult to diagnose and treat. Mortality is high and optimal treatment is unknown. We compared clinical outcomes of drug-resistant and -susceptible TBM treated with either standard or intensified antituberculosis treatment. We analyzed the influence of Mycobacterium tuberculosis drug resistance on the outcomes of patients with TBM enrolled into a randomized controlled trial comparing a standard, 9-month antituberculosis regimen (containing rifampicin 10 mg/kg/day) with an intensified regimen with higher-dose rifampicin (15 mg/kg/day) and levofloxacin (20 mg/kg/day) for the first 8 weeks. The primary endpoint of the trial was 9-month survival. In this subgroup analysis, resistance categories were predefined as multidrug resistant (MDR), isoniazid resistant, rifampicin susceptible (INH-R), and susceptible to rifampicin and isoniazid (INH-S + RIF-S). Outcome by resistance categories and response to intensified treatment were compared and estimated by Cox regression. Of 817 randomized patients, 322 had a known drug resistance profile. INH-R was found in 86 (26.7%) patients, MDR in 15 (4.7%) patients, rifampicin monoresistance in 1 patient (0.3%), and INH-S + RIF-S in 220 (68.3%) patients. Multivariable regression showed that MDR (hazard ratio [HR], 5.91 [95% confidence interval {CI}, 3.00-11.6]), P < .001), was an independent predictor of death. INH-R had a significant association with the combined outcome of new neurological events or death (HR, 1.58 [95% CI, 1.11-2.23]). Adjusted Cox regression, corrected for treatment adjustments, showed that intensified treatment was significantly associated with improved survival (HR, 0.34 [95% CI, .15-.76], P = .01) in INH-R TBM. Early intensified treatment improved survival in patients with INH-R TBM. Targeted regimens for drug-resistant TBM should be further explored

CSA: Thực hành nông nghiệp thông minh với khí hậu ở Việt Nam

During the last five years, Vietnam has been one of the countries most affected by climate change. Severe typhoons, flooding, cold spells, salinity intrusion, and drought have affected agriculture production across the country, from upland to lowland regions. Fortunately for Vietnam, continuous work in developing climate-smart agriculture has been occurring in research organizations and among innovative farmers and entrepreneurs. Application of various CSA practices and technologies to adapt to the impact of climate change in agriculture production have been expanding. However, there is a need to accelerate the scaling process of these practices and technologies in order to ensure growth of agriculture production and food security, increase income of farmers, make farming climate resilient, and contribute to global climate change mitigation. This book aims to provide basic information to researchers, managers, and technicians and extentionists at different levels on what CSA practices and technologies can be up scaled in different locations in Vietnam

THE IMPACT OF FOREIGN INVESTORS' ABNORMAL TRADING ON THE ABNORMAL RETURNS OF BANKING SECTOR STOCKS: THE CASE OF VIETNAM

This study aims to analyze the impact of foreign investors' abnormal trading on the abnormal returns of banking sector stocks in Vietnam from 2006 to 2023. The data sample includes 631 abnormal buy events, 571 abnormal buy events on net purchase days, 477 abnormal sell events, and 432 abnormal sell events on net sell days of foreign investors. The study employs the event study methodology with parametric and non-parametric tests. The results show that abnormal buy events and abnormal buy events on net purchase days by foreign investors convey positive information and have a positive impact on stock prices, creating positive abnormal returns, with stock prices forming new equilibrium levels. Abnormal sell events and abnormal sell events on net sell days convey negative information and have a negative impact on stock prices in the short term, after which prices tend to return to their initial states as before the events. The study suggests that investors can observe foreign investors' trading behavior as reference information in their investment decisions regarding banking sector stocks. Furthermore, it recommends that the government consider relaxing the "room" limit on foreign ownership in Vietnamese commercial banks to align with the objective of upgrading the stock market

Trajectory tracking control based on genetic algorithm and proportional integral derivative controller for two-wheel mobile robot

This paper uses the genetic algorithm (GA) to optimize the proportional integral derivative (PID) controller parameters to present the motion control design for a two-wheeled mobile robot autonomous system. The GA algorithm determines a collision-free travel curve for a robot with a tangential velocity restriction constraint. A trajectory-tracking controller based on the PID control structure is developed to monitor the calculated route curves for the mobile robot. Simulation results show the effectiveness of the GA-PID controller compared to the PID controller. The GA-PID controller demonstrates improved performance in trajectory tracking and collision avoidance, making it suitable for controlling the motion of two-wheeled mobile robots. The GA's optimization process allows for better tuning of the PID controller parameters, resulting in more efficient and accurate robot motion control. The results suggest that the proposed GA-PID controller is a promising approach for enhancing mobile robots' autonomous navigation capabilities

Hematological parameters of red tilapia (Oreochromis sp.) fed lemongrass essential oil (Cymbopogon citratus) after challenge with Streptococcus agalactiae

The study involved feeding lemongrass essential oil (LEO) supplements to red tilapia (Oreochromis sp.) at concentrations including Control - 0 mg, T1 – 200 mg, T2 – 300 mg, and T3 – 400 mg per kg of feed. The research investigated changes in hematological (HCT, Hb, RBC, WBC & thrombocytes) and erythrocyte’s morphological (major/minor axis; perimeter, and area of erythrocyte) parameters before infection, 5- and 10-days post-infection (DPI). According to analytical findings, a diet containing LEO enhanced the synthesis of both erythrocytes and leukocytes in the peripheral blood of red tilapia after 20 days of being used. Therefore, the indicators of this group of fish showed better performance than those that did not use LEO supplement five days after bacterial infection. Fish fed 200 mg/kg of LEO after being challenged with S. agalactiae for ten days showed an improved effect on red blood cell production. White blood cells decreased at all concentrations because of citral’s immunomodulatory properties